An Overview of the Measurement of Permeability of Composite Reinforcements

Liquid composite molding (LCM) is a class of fast and cheap processes suitable for the fabrication of large parts with good geometrical and mechanical properties. One of the main steps in an LCM process is represented by the filling stage, during which a reinforcing fiber preform is impregnated with a low-viscosity resin. Darcy’s permeability is the key property for the filling stage, not usually available and depending on several factors. Permeability is also essential in computational modeling to reduce costly trial-and-error procedures during composite manufacturing. This review aims to present the most used and recent methods for permeability measurement. Several solutions, introduced to monitor resin flow within the preform and to calculate the in-plane and out-of-plane permeability, will be presented. Finally, the new trends toward reliable methods based mainly on non-invasive and possibly integrated sensors will be described

Effects of tanniferous browse plant supplementation on the nutrient digestibility and growth of Djallonk rams

Two separate experiments were conducted to investigate the effect of tanniferous (CT) browse plant supplementation on the growth, nutrient digestibility and blood biochemical properties of Djallonké sheep. The browse plants were Albizia lebbeck, Gmelina arborea, Senna siamea and Ceiba pentandra and were harvested from natural grazing fields within the vicinity of Nyankpala in Ghana. In experiment I, 20 semi-intensively kept Djallonké rams with average initial weight of 12.8±1.7 kg were randomly assigned four browse plants to evaluate their performance in terms of growth and blood biochemical properties. In experiment II, eight intensively managed Djallonké rams with an average initial weight of 13.8±1.56 kg were randomly assigned to a total mixed ration (TMR) made of browse plants, rice straw, minerals and vitamins to determine the nutrient digestibility. In experiment I, whereas lambs supplemented with the highest condensed tannin (CT) browse plant (C. Pentandra) had improved (P<0.05) ADWG compared to the control, it did not differ from the ADWG reported in lambs that were supplemented with A. lebbeck even though it did not contain measurable levels of CT. The blood metabolites did not differ among treatments. In experiment II, lambs fed with S. siamea ration had the lowest DMI with the highest reported in G. arborea. Lambs fed with A. lebbeck TMR had the highest (P<0.05) CP digestibility and nitrogen balance. The lowest NDF and ADF digestibility were obtained in animals fed the G. arborea diet. The tanniferous browse plants used in this experiment were high in nutritive value and resulted in improved live weight of lambs. They could be fed as supplement to lambs grazing natural pasture during periods of feeds scarcity

Multicentric Castleman's Disease in a Ghanaian Adult

Castleman’s disease is a rare cause of lymphoid hyperplasia that may result in localized symptoms or an aggressive, multisystem disorder that can mimic other diseases like lymphoma or tuberculosis. We describe a case of a 55-year-old Ghanaian male who was successfully diagnosed and managed for multicentric Castleman’s disease with combination chemotherapy.Keywords: multicentric Castleman’s disease, Plasma cell, lymphadenopathy, chemotherapy, Rituxima

Feed resource availability and fodder markets in northern Ghana

United States Agency for International Developmen

Bleomycin-induced pneumonitis in a young Ghanaian male with Hodgkin’s Lymphoma

We report a case of a young Ghanaian male who developed Bleomycin Induced Pneumonitis (BIP) after being treated for Hodgkin’s Lymphoma. Pulmonary toxicity is the most feared complication of bleomycin therapy despite its effectiveness in achieving cure in patients with Hodgkin’s lymphoma and germ cell tumors. BIP has a significant mortality rate if detected late and a high index of suspicion is required in all patients on bleomycin-based therapies with sudden onset of respiratory symptoms

Adherence to hydroxyurea therapy and health-related quality of life in children with sickle cell anaemia at Korle Bu Teaching Hospital in Ghana

Background: Sickle cell anaemia (SCA) causes numerous acute and chronic complications, which can result in significant morbidity and mortality. Hydroxyurea (HU) therapy in individuals with SCA is associated with a reduction in disease severity.Objective: The study aimed to determine the relationship between adherence to HU therapy and health-related quality of life (HRQOL) scores in children with SCA (HbSS) at Korle Bu Teaching Hospital (KBTH) and identify any barriers to HU adherence.Methods: A cross-sectional descriptive study was conducted at the paediatric sickle cell clinic of the KBTH. One hundred and fifteen children aged 2 – 12 years with HbSS receiving HU therapy and their primary caregivers were enrolled on this study. Demographic and HU-related data were obtained from medical records and interviews with caregivers. The 8-item Morisky Medication Adherence Scale (MMAS-8©) and haematologic response based on mean corpuscular volume (MCV) were used to assess HU adherence. Caregivers and children aged 8 - 12 years also completed the Paediatric Quality of Life Inventory (PedsQLTM) SCD-module version 3.0. For children aged 5 – 7 years, the PedsQLTM SCD-module version 3.0 was administered by interview.Results: Seventy-nine (68.7%) of children had high adherence to HU therapy using the MMAS-8©. The mean PedsQLTM scores were 96.9 ± 6.0 and 96.3 ± 7.2 for the child (n = 91) and caregiver (n = 114), respectively. Children with high HU adherence had significantly higher PedsQLTM scores than those with low or moderate adherence. Neither child's current MCV nor mean change in MCV correlated with child or caregiver PedsQLTM scores. The main barrier to HU adherence identified by children aged 8 years was forgetfulness, while the cost of HU was the main barrier to adherence reported by caregivers.Conclusion: Children with SCA with high adherence to HU had the highest HRQOL scores using the PedsQLTM SCD-module version 3.0. Routine assessment of barriers to HU adherence can provide important information to help guide relevant interventions