Clinical correlation between serum uric acid level and tophus involmente of tendon: a descriptive study

Background: Clinical correlation between serum uric acid level and tophus involvement of tendon.Methods: This is a non randomised multicetric prospective study carried out from December 2015 to May 2018. This is a descriptive study comprising 108 patients with diagnosis of gout according to the American College of Rheumatology (ACR) criteria. US examination included the quadriceps tendons, the patellar Tendon, peroneus tendon and the Achilles tendon. All tendons were evaluated bilaterally according to the EULAR guidelines for performing US in rheumatology.Results: We included the patients aged between 20-60 year. In this study male patients was 86 (79.63% ) and 22 (20.37%) patient were female. In this study 108 patients with serum uric acid level between 5.5 -9.0 mg/dl with age from 20 yr to 60 yr were studied. Uric acid level between 7 - 9 mg/dl found in 68.48% and it was in age between 30–45 yr of age. 73 patiens (67.59%) had pain at enthesis for at least once before inclusion in the study. Intra-tendinous tophi and hyperechoic aggregates were the most frequent lesions at the tendon in US examinations. In our study Patellar tendon is the most frequently involved tendon followed by quadriceps, Achilles and peroneus tendon.Conclusions: Tophius involvement of tendon in the lower limbs in gout is very frequent, particularly at the patellar tendon, Quadriceps tendon and Achilles tendon

Drotaverine hydrochloride versus valethamate bromide for cervical dilatation in labour: a comparative study

Background: Labor is the most perilous journey a woman has to undertake. Painless and short labor is desired by every woman and is a constant aim for obstetrician. Objective of this study was to compare the efficacy of drotaverine hydrochloride with valethamate bromide for cervical dilatation in labor in primigravida.Methods: The present study was conducted in the department of obstetrics and gynecology, S. P. Medical College and Associated Group of Hospitals, Bikaner, Rajasthan from 1st August 2018 to 31st July 2019 over a period of 1 year. Total of 300 patients were included in the study with 150 patients in each of the two groups. In this study the effects of Drotaverine hydrochloride (Group A) and Valethamate bromide (Group B) on cervical dilatation were compared.Results: In our study, the mean drug delivery interval was 101.58±78.06 mins in Group A and 134.24±94.12 mins in Group B. The mean number of doses of drug required was 1.27±0.55 in Group A and 4.17±1.62 in Group B.  The difference was statistically highly significant (p <0.001).Conclusions: Drotaverine hydrochloride is found to be better than valethamate bromide in shortening the duration of active phase of labor in primigravidae. Drotaverine was found to be a better drug, hence, can be used to reduce the agony of the laboring woman without any significant side effects on the mother or the fetus

FORMULATION AND EVALUATION OF ITOPRIDE HCL SUSTAINED RELEASED PELLETS

The present work was aimed at formulation development, evaluation and comparative study of the effects of ethyl cellulose in Itopride HCL CR pellets. The controlled release polymers used for the present study were Ethylcellulose N-14 and Ethylcellulose N-20. The formulated pellets were evaluated for various pellet properties, like hardness, bulk density, tapped density, cars index and dissolution rate. Comparative evaluation of the above-mentioned parameters established the superiority of the pellets formulated with Ethylcellulose those formulated with different grades

BRAIN-COMPUTER-INTERFACE: VARIOUS SIGNAL ACQUISITION APPROACHES

This article addresses to the fundamental approaches for signal acquisition in Brain-Computer-Interface technology. Signal acquisition approaches are broadly classified into three major categories as Invasive-Approach, Semi-Invasive-Approach and Non-Invasive-Approach. In this context first of all we discussed the invasive approach in which electrical signals to be extracted from gray matter of the brain by neurosurgery, than semi invasive approach discussed in which electrical signals to be extracted from outside the gray matter by using electrocorticography technique. After that we discussed non invasive approach in detail including various techniques as EEG, MEG, EMG, MRI, TMS, PET, CT, NIRS, EROS, fNIRS, and fMRI. Keywords: Neurosurgery, Craniotomy, SQUID, Radioactive Tracer, Multivariate Calibration

Hand Gesture Recognition using Python

The goal for the project was to develop a new type of Human Computer Interaction system that subdues the problems that users have been facing with the current system. The project is implemented on a Linux system but could be implemented on a windows system by downloading some modules for python. The algorithm applied is resistant to change in background image as it is not based on background image subtraction and is not programmed for a specific hand type; the algorithm used can process different hand types, recognizes no of fingers, and can carry out tasks as per requirement. As it is stated within this paper, the main goals were reached. The application is capable of the gesture recognition in real-time. There are some limitations, which we still have to be overcome in future

Diversity of Exopolysaccharide Producing Fungi from Foot Hills of Shivalik Ranges of Chandigarh Capital Region

In this investigation, the diversity of exopolysaccharide producing fungi of foot hills of Shivalik ranges of Chandigarh capital region have been studied. The study resulted in isolation of a total of 94 fungal isolates of which 52 isolates belonging to 17 different genera viz., Agaricus, Alternaria, Aspergillus, Aureobasidium, Candida, Curvullaria, Chaetomium, Fusarium, Ganoderma, Penicillium, Pleurotus, Polyporous, Rhizopus,  Saccharomyces, Stemophylium, Termitomyces, and Tricholoma etc. were found to possess the EPS producing potential. These isolates have been categorized into five different groups on the basis of the EPS quantities they produced. These included Group I with production range of : &gt; 1g/l ; Group II with production range of : 1-2 g/l ; Group III with production  range of : 2-3 g/l ; Group IV with production range of : 3-4 g/l and Group V with production range of : 4-5 g/l. Out of these 52 EPS producing isolates, 11 were found to be the prominent producers with Auerobasidium RYLF 10 as the most potential isolate with EPS concentration of 4.60g/l followed by the species of Penicillium RYLF 35, Aspergillus RYLF 17 and Ganoderma RYMF 15. No correlation between EPS concentration and the biomass yield could be traced

Study of Microstrip filters

Volume 2 Issue 1 (January 2014

Crigler-Najjar Syndrome Type 2 in an Adult: A Rare Presentation

Introduction: Crigler-Najjar syndrome type 2 (CNS type 2) is a rare disorder that causes elevated levels of bilirubin in the blood (nonhemolytic unconjugated hyperbilirubinemia). The main symptom of CNS type 2 is persistent jaundice. It is caused by genetic changes in the UGT1A1 gene and the inheritance is autosomal recessive. Genetic testing of the UGT1A1 gene for mutations is the diagnostic clincher. We report one such rare case. Case report: A 75-year-old male presented with history of right-sided weakness with right-sided facial weakness, MRI brain revealed an infarct in the left side of brain with general physical findings suggestive of icterus. Conclusion: Diagnosing and managing these patients may be challenging. Our aim is to draw attention of the treating physicians towards this disease with the help of this case report

Outcomes of Sphincter of Oddi Manometry When Performed in Low Volumes

Background. Sphincter of Oddi manometry is a highly specialized procedure associated with an increased risk of procedural complications. Published studies have typically been performed in large volume manometry centers. Objective. To examine the outcomes and complication rate of SOM when performed in small volumes. Design. Retrospective analysis at a tertiary care referral hospital that infrequently performs Sphincter of Oddi manometry. Patient records were reviewed for procedural details, patient outcomes, and complications after sphincter of Oddi manometry. Results. 36 patients, 23 (23 type II sphincter of Oddi dysfunction (SOD), 13 type III SOD) underwent sphincter of Oddi manometry and were followed up for mean of 16 months. Nine Type II patients (90%) with elevated basal sphincter pressures noted symptom improvement after sphincterotomy compared with only 3 patients (43%) of the patients with normal basal pressures. In type III SOD, 7 patients had elevated basal SO pressure and underwent sphincterotomy. Three patients (43%) improved. There were six (16%) procedure-related complications. There were four cases of post ERCP pancreatitis (11%), all of which were mild. Conclusion. In low numbers, sphincter of Oddi manometry can be performed successfully and safely by experienced biliary endoscopists with results that are comparable to large volume centers