Exomoon simulations

We introduce and describe our newly developed code that simulates light curves and radial velocity curves for arbitrary transiting exoplanets with a satellite. The most important feature of the program is the calculation of radial velocity curves and the Rossiter-McLaughlin effect in such systems. We discuss the possibilities for detecting the exomoons taking the abilities of Extremely Large Telescopes into account. We show that satellites may be detected also by their RM effect in the future, probably using less accurate measurements than promised by the current instrumental developments. Thus, RM effect will be an important observational tool in the exploration of exomoons.Comment: 5 pages, 2 figures with 9 figure panels, accepted by EM&

Reanalysis of two eclipsing binaries: EE Aqr and Z Vul

We study the radial-velocity and light curves of the two eclipsing binaries EE Aqr and Z Vul. Using the latest version of the Wilson & Van Hamme (2003) model, absolute parameters for the systems are determined. We find that EE Aqr and Z Vul are near-contact and semi-detached systems, respectively. The primary component of EE Aqr fills about 96% of its 'Roche lobe', while its secondary one appears close to completely filling this limiting volume. In a similar way, we find fill-out proportions of about 72 and 100% of these volumes for the primary and secondary components of Z Vul respectively. We compare our results with those of previous authors.Comment: 13 pages, 8 figures, 10 table

Particle interactions with single or multiple 3D solar reconnecting current sheets

The acceleration of charged particles (electrons and protons) in flaring solar active regions is analyzed by numerical experiments. The acceleration is modelled as a stochastic process taking place by the interaction of the particles with local magnetic reconnection sites via multiple steps. Two types of local reconnecting topologies are studied: the Harris-type and the X-point. A formula for the maximum kinetic energy gain in a Harris-type current sheet, found in a previous work of ours, fits well the numerical data for a single step of the process. A generalization is then given approximating the kinetic energy gain through an X-point. In the case of the multiple step process, in both topologies the particles' kinetic energy distribution is found to acquire a practically invariant form after a small number of steps. This tendency is interpreted theoretically. Other characteristics of the acceleration process are given, such as the mean acceleration time and the pitch angle distributions of the particles.Comment: 18 pages, 9 figures, Solar Physics, in pres

K2-60b and K2-107b. A Sub-Jovian and a Jovian Planet from the K2 Mission

FWN – Publicaties zonder aanstelling Universiteit LeidenStars and planetary system

TOI-544 b: a potential water-world inside the radius valley in a two-planet system

Stars and planetary system

Three Small Planets Transiting a Hyades Star

Stars and planetary system

Identification of regulatory variants associated with genetic susceptibility to meningococcal disease

Non-coding genetic variants play an important role in driving susceptibility to complex diseases but their characterization remains challenging. Here, we employed a novel approach to interrogate the genetic risk of such polymorphisms in a more systematic way by targeting specific regulatory regions relevant for the phenotype studied. We applied this method to meningococcal disease susceptibility, using the DNA binding pattern of RELA - a NF-kB subunit, master regulator of the response to infection - under bacterial stimuli in nasopharyngeal epithelial cells. We designed a custom panel to cover these RELA binding sites and used it for targeted sequencing in cases and controls. Variant calling and association analysis were performed followed by validation of candidate polymorphisms by genotyping in three independent cohorts. We identified two new polymorphisms, rs4823231 and rs11913168, showing signs of association with meningococcal disease susceptibility. In addition, using our genomic data as well as publicly available resources, we found evidences for these SNPs to have potential regulatory effects on ATXN10 and LIF genes respectively. The variants and related candidate genes are relevant for infectious diseases and may have important contribution for meningococcal disease pathology. Finally, we described a novel genetic association approach that could be applied to other phenotypes