Patient- and parent-reported outcome measures of developmental adaptive abilities in visually impaired children: The Visual Impairment Developmental Autonomy (VIDA) scale

In the pediatric context, parents’ and patients’ engagement in the care process is strongly recommended and could be pursued using patient-reported outcome measures (PROMs), which therefore become useful for planning and monitoring treatments. Nevertheless, few data are available from families of children with neurodevelopmental disorders such as visual impairment (VI). The Visual Impairment Developmental Autonomy (VIDA) project aims to develop and validate a patient- and parent-reported tool to measure the most relevant aspects concerning everyday adaptive abilities in children and adolescents with visual impairment: the VIDA scale. The present paper illustrates the Delphi process of item generation engaging parents and patients and presents a protocol for the validation of this new co-designed tool in an Italian visually impaired pediatric population. Twenty-three families and five adolescents provided a list of 192 items and assessed their relevance. Items were categorized in 5 areas of adaptive abilities (i.e., table manners, clothing, personal hygiene, orientation and mobility, and socio-affectivity) and into three age ranges based on the patient's age. The final 102-item Vida Scale will be administered to a minimum of 300 visually impaired children together with measures of quality of life and child adjustment to investigate its psychometric properties

An intervention in order to develop and strengthen the adapted physical activity in school: the experience in the Pavia area

The formative tools, currently available in school, are inadequate to satisfy the requirements of the ministerial curriculum. The realization of a project, whose aim is the integration and the actual development of meaningful didactically activities is possible. It is desirable throuth a net's system to propose offered didactic meaningful offered within the APA, trough the organization coordinated by the territorial potentialities

An intervention in order to develop and strengthen the adapted physical activity in school: the experience in the Pavia area

The formative tools, currently available in school, are inadequate to satisfy the requirements of the ministerial curriculum. The realization of a project, whose aim is the integration and the actual development of meaningful didactically activities is possible. It is desirable throuth a net's system to propose offered didactic meaningful offered within the APA, trough the organization coordinated by the territorial potentialities

Project of adapted physical activity in houses for assisted elderly people

This project is a new experimentation in which houses for assisted elderly people can be a place for physical activity in order to support, improve and increase the autonomy of everyone. The intervention has led to a good physical and perceptive autonomy. Besides, we observed inclusion between physical and perceptive autonomy. Besides, we observed inclusion between physical and relational encourages, cooperation with operative groups and between the groups

Coordination chemistry of N-aminopropyl pendant arm derivatives of mixed N/S-, and N/S/O-donor macrocycles, and construction of selective fluorimetric chemosensors for heavy metal ions

The coordination chemistry of the N-aminopropyl pendant arm derivatives (L 1c-4c) of the mixed donor macrocyclic ligands [12]aneNS 2O, [12]aneNS 3, [12]aneN 2SO, and [15]aneNS 2O 2 (L 1a-4a) towards Cu II, Zn II, Cd II, Hg II, and Pb II in aqueous solution has been investigated. The protonation and stability constants with the aforementioned metal ions were determined potentiometrically and compared, where possible, with those of the unfunctionalised macrocycles. The measured values show that Hg II and Cu II in water have the highest affinity for all ligands considered, with the N-aminopropyl pendant arm weakly coordinating the metal centres. Crystals suitable for X-ray diffraction analysis were grown for the perchlorate salt (H 2L 1c)(ClO 4) 2·dmf, and for the 1:1 complexes [Cd(L 3a)(NO 3) 2] (1), [Cu(L 4a)(dmf)](ClO 4) 2 (2), [Zn(L 1c)(ClO 4)]ClO 4 (3), [Cd(L 1c)(NO 3)]NO 3 (4), and [Hg(L 2c)](ClO 4) 2 (5). Their structures show the macrocyclic ligands adopting a folded conformation, which for the 12-membered systems can be either [2424] or [3333] depending on the nature of the metal ion. L 1c-4c were also functionalised at the primary amino pendant group with different fluorogenic subunits. In particular the N-dansylamidopropyl (L nd, n = 1-4), and the N-(9-anthracenylmethyl)aminopropyl (L ne, n = 1, 2, 4, Scheme 1) pendant arm derivatives of L 1a-4a were synthesised and their optical responses to the above mentioned metal ions were investigated in MeCN/H 2O (4: 1 v/v) solutions