28-jähriger Patient mit erfolgreich behandelter dilatativer Kardiomyopathie

Zusammenfassung: Ein 28-jähriger Patient wurde mit dekompensierter Herzinsuffizienz notfallmäßig zugewiesen. In der Vorgeschichte bestand ein hypogonadotroper Hypogonadismus. Echokardiographisch fand sich eine dilatative Kardiomyopathie. Ein erhöhtes Serumferritin und eine Eisenüberladung in der Leberbiopsie ließen eine hereditäre Hämochromatose vermuten. Die kardiale Beteiligung konnte mittels Magnetresonanztomographie nachgewiesen werden. Genetische Abklärungen ergaben eine homozygote Mutation für G320V und bewiesen eine juvenile Hämochromatose. Eine Aderlasstherapie führte innerhalb eines Jahres zur Normalisierung des Eisenstatus und der kardialen Pumpfunktio

Probing Electroweak Top Quark Couplings at Hadron Colliders

We consider QCD t\bar{t}\gamma and t\bar{t}Z production at hadron colliders as a tool to measure the tt\gamma and ttZ couplings. At the Tevatron it may be possible to perform a first, albeit not very precise, test of the tt\gamma vector and axial vector couplings in t\bar{t}\gamma production, provided that more than 5 fb^{-1} of integrated luminosity are accumulated. The t\bar{t}Z cross section at the Tevatron is too small to be observable. At the CERN Large Hadron Collider (LHC) it will be possible to probe the tt\gamma couplings at the few percent level, which approaches the precision which one hopes to achieve with a next-generation e^+e^- linear collider. The LHC's capability of associated QCD t\bar{t}V (V=\gamma, Z) production has the added advantage that the tt\gamma and ttZ couplings are not entangled. For an integrated luminosity of 300 fb^{-1}, the ttZ vector (axial vector) coupling can be determined with an uncertainty of 45-85% (15-20%), whereas the dimension-five dipole form factors can be measured with a precision of 50-55%. The achievable limits improve typically by a factor of 2-3 for the luminosity-upgraded (3 ab^{-1}) LHC.Comment: Revtex3, 30 pages, 9 Figures, 6 Table

Laser-Cluster-Interaction in a Nanoplasma-Model with Inclusion of Lowered Ionization Energies

The interaction of intense laser fields with silver and argon clusters is investigated theoretically using a modified nanoplasma model. Single pulse and double pulse excitations are considered. The influence of the dense cluster environment on the inner ionization processes is studied including the lowering of the ionization energies. There are considerable changes in the dynamics of the laser-cluster interaction. Especially, for silver clusters, the lowering of the ionization energies leads to increased yields of highly charged ions.Comment: 10 pages, 11 figure

Runaway electron synchrotron radiation in a vertically translated plasma

Synchrotron radiation observed from runaway electrons (REs) in tokamaks depends upon the position and size of the RE beam, the RE energy and pitch distributions, as well as the location of the observer. We show that experimental synchrotron images of a vertically moving runaway electron beam sweeping past the detector in the TCV tokamak agree well with predictions from the synthetic synchrotron diagnostic Soft. This experimental validation lends confidence to the theory underlying the synthetic diagnostics which are used for benchmarking theoretical models of and probing runaway dynamics. We present a comparison of synchrotron measurements in TCV with predictions of kinetic theory for runaway dynamics in uniform magnetic fields. We find that to explain the detected synchrotron emission, significant non-collisional pitch angle scattering as well as radial transport of REs would be needed. Such effects could be caused by the presence of magnetic perturbations, which should be further investigated in future TCV experiments.Comment: 7 pages, 4 figures. Accepted for publication in Nuclear Fusio