37 research outputs found
Image processing mini manual
The intent is to provide an introduction to the image processing capabilities available at the Langley Research Center (LaRC) Central Scientific Computing Complex (CSCC). Various image processing software components are described. Information is given concerning the use of these components in the Data Visualization and Animation Laboratory at LaRC
Plasma tau complements CSF tau and P-tau in the diagnosis of Alzheimer's disease
Introduction: Plasma tau may be an accessible biomarker for Alzheimer’s disease (AD), but the
correlation between plasma and cerebrospinal fluid (CSF) tau and the value of combining plasma
tau with CSF tau and phospho-tau (P-tau) are still unclear.
Methods: Plasma-tau, CSF-tau, and P-tau were measured in 97 subjects, including elderly cognitively normal controls (n 5 68) and patients with AD (n 5 29) recruited at the NYU Center
for Brain Health, with comprehensive neuropsychological and magnetic resonance imaging
evaluations.
Results: Plasma tau was higher in patients with AD than cognitively normal controls (P , .001,
area under the receiver operating characteristic curve 5 0.79) similarly to CSF tau and CSF
P-tau and was negatively correlated with cognition in AD. Plasma and CSF tau measures
were poorly correlated. Adding plasma tau to CSF tau or CSF P-tau significantly increased
the areas under the receiver operating characteristic curve from 0.80 and 0.82 to 0.87 and
0.88, respectively.
Discussion: Plasma tau is higher in AD independently from CSF-tau. Importantly, adding plasma tau
to CSF tau or P-tau improves diagnostic accuracy, suggesting that plasma tau may represent a useful
biomarker for AD, especially when added to CSF tau measures
Short communication : the dissolution of UK simulant vitrified high-level-waste in groundwater solutions
Dissolution of a simulant UK nuclear waste glass containing Mg, Ca and Zn was investigated over 35 d at 50 °C in water and simulant groundwater solutions. The dissolution rates were influenced subtly by the groundwater composition, following the trend, from least to most durable: clay > water > granite ≈ saline. Solutions were rapidly silica saturated but boron dissolution rates continued to increase. This is hypothesised to be due to the formation of secondary Mg-silicate precipitates, preventing the formation of a passivating silica gel layer and allowing glass dissolution to proceed at close to the maximum rate
Low incidence of SARS-CoV-2, risk factors of mortality and the course of illness in the French national cohort of dialysis patients
Caractéristiques des plaies chroniques chez les toxicomanes : étude rétrospective de 58 patients
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