Developing a Data Analysis Pipeline for Novel Bio-Logging Tools

HonorsPsychologyUniversity of Michiganhttp://deepblue.lib.umich.edu/bitstream/2027.42/169389/1/debho.pd

Marriage, Registration and Dissolution by Same-Sex Couples in the U.S.

This study analyzes data from states that have extended legal recognition to same-sex couples. Analyses show that same-sex couples want and use these new legal statuses. Furthermore, they react more enthusiastically when marriage is possible. More than 40% of same-sex couples have formed legal unions in states where such recognition is available. Same-sex couples prefer marriage over civil unions or domestic partnerships. In the first year that marriage was offered in Massachusetts, 37% of same-sex couples there married. In states that offered civil unions, only 12% of same-sex couples took advantage of this status in the first year and only 10% did so in states with domestic partnership registrie

A Test of Expectancy Theory and Demographic Characteristics as Predictors of Faking and Honesty in Employment Interviews

Job applicants vary in the extent to which they fake or stay honest in employment interviews, yet the contextual and demographic factors underlying these behaviors are unclear. To help answer this question, we drew on Ellingson and McFarland’s (2011) framework of faking based in valence-instrumentality-expectancy theory. Study 1 collected normative data and established baseline distributions for instrumentality-expectancy beliefs from a Canadian municipality. Results indicated that most respondents had low levels of instrumentality-expectancy beliefs for faking, but high levels for honesty. Moreover, income, education, and age were antecedents of instrumentality-expectancy beliefs. Study 2 extended these findings with a United States sample and sought to determine if they could be explained by individual differences. Results demonstrated that financial insecurity predicted instrumentality of faking, whereas age predicted expectancy of faking. Finally, valence-instrumentality-expectancy beliefs were all predictors of self-reported faking in a past interview

Differentiation of biosolids from animal faecal material using the 16s ribosomal RNA genetic markers of gastrointestinal anaerobic bacteria

Recombinant DNA techniques were evaluated for their usefulness in distinguishing biosolids from faecal material of cow, kangaroo and sheep. It involved PCR amplification using published priming sequences, and restriction site profiling of amplified DNA across the 16S rRNA gene of anaerobic gastrointestinal bacteria, Bacteroides spp and Bifidobacteria spp. Of the three Bacteroides spp primer pairs, two were useful for cow faecal material though at lower annealing temperatures were also applicable to biosolids and sheep faecal material. The third primer pair was specific only for biosolids. All three primer pairs were not able to PCR-amplify Bacteroides spp sequences in faecal material of kangaroo. Of the three Bifidobacteria spp primer pairs, one was useful for sheep faecal material though at lower annealing temperature was also applicable to biosolids and cow and kangaroo faecal material. The Bifidobacterium angulatum specific primer pair enabled the PCR detection of anaerobes only in biosolids and in faecal material of kangaroo. The third, a Bifidobacterium catenulatum specific primer pair was suitable for faecal material of cow and at lower annealing temperatures was also applicable to the sample from sheep. For some primer sets, PCR amplification alone could not differentiate biosolids from other faecal samples. However, this could be resolved by digesting amplified DNA with the appropriate restriction enzymes. Overall, our evaluations show that recombinant DNA techniques have the potential to distinguish biosolids from other sources of faecal material, including that from kangaroo

Maximizing bidder’s profit in online auctions using grey system theory predictor agent

Purpose – As the demand for online auctions increases, the process of monitoring multiple auction houses, deciding which auction to participate in and making the right bids, become challenging tasks for consumers. Hence, knowing the closing price of a given auction would be an advantage, since this information will ensure a win in a given auction. However, predicting a closing price for an auction is not easy, since it is dependent on many factors. The purpose of this paper is to report on a predictor agent that utilises grey system theory to predict the closing price for a given auction. Design/methodology/approach – The focus of the research is on grey system agent. This paper reports on the development of a predictor agent that attempts to predict the online auction closing price in order to maximise the bidder's profit. The performance of this predictor agent is compared with two well‐known techniques, the Simple Exponential Function and the Time Series, in a simulated auction environment and in the eBay auction. Findings – The grey theory agent gives a better result when less input data are made, while the Time Series Agent can be used with the availability of a lot of information. Although the Simple Exponential Function Agent is able to predict well with less input data, it is not an appropriate method to be applied in the prediction model since its formula is not realistic and applicable in predicting the online auction closing price. The experimental results also showed that using moving historical data produces a higher accuracy rate than using fixed historical data for all three agents. Originality/value – Grey system theory prediction model, GM(1, 1) has not been applied in online auction prediction. In this paper the authors have applied grey theory into an agent to predict the closing price of an online auction, in order to increase the profit of bidders in the bidding stage. The experimental results show that the accuracy of the grey prediction model is more then 90 per cent, with less then eight historical data inputs

Adapting an Elementary School Nutrition Context Assessment for High School Settings and Students

The school nutrition context is comprised of supportive environmental features, programs, policies, and social relationships that shape students’ healthy dietary choices and patterns. When engaging students as change agents, advocates, and partners in making healthy nutrition choices easier, environmental assessment tools developed for adults may be too complex or inappropriately tailored for youth. Adolescents need practical, user-tailored tools that reliably measure the food and beverage environments they encounter in school to inform youth-led changes to the school nutrition context. To meet this need, an evidence-based school environmental assessment was adapted for use in high schools by students as evaluators. Cooperative Extension educators engaged students in experiential learning to adapt the nutrition component of an environmental tool (SPAN-ET) designed for elementary school contexts to high school applications. The resulting tool is a comprehensive nutrition-specific adaptation that incorporates considerations of food security, structures for youth-driven data collection, and data-identified areas for action. The tool was adapted in one high school setting and piloted in three additional high schools. Student-generated data were used to prioritize and plan policy, systems, and environmental strategies aimed at increasing healthy food/beverage access and supporting healthy eating/drinking behaviors to reduce hunger and obesity risk factors in schools

“They are dealing with people’s lives…”: Diagnostic and post-diagnostic healthcare experiences in primary progressive aphasia

Purpose: The healthcare experience is a multifaceted and varied process, particularly for people living with complex conditions such as primary progressive aphasia (PPA). Different experiences influence pathways through the health system, impacting client outcomes. To our knowledge, no previous studies have directly explored the healthcare experiences of people with PPA and their families. This study aimed to explore the experiences of people living with PPA from the perspective of both the person with PPA and their families during diagnostic and post-diagnostic phases, and to identify factors influencing service access and perceptions of quality of care. Method: The study followed an Interpretive Phenomenological Analysis (IPA) approach. In-depth, semi-structured interviews were completed with three people with PPA and their primary care partner, and two further care partners of people with PPA. Result: Five superordinate themes were identified: characterising the assessment experience, getting a diagnosis, moving beyond the diagnosis, participant interactions with clinicians, and overall service provision. The five superordinate themes comprised 14 subthemes. Conclusion: The study provides preliminary insights into the complexity of the PPA healthcare journey, and the need for increased accessibility of information and supports following diagnosis. The findings inform recommendations for improving quality of care and the development of a PPA service framework or care pathway

Monitoring of waterways for evidence of faecal contamination from biosolids using DNA techniques.

Increased nutrient levels in inland waterways have led to algal blooms and eutrophication in many agricultural regions. To ensure fertiliser inputs are managed more effectively, the source of contamination needs to be tracked and identified. Point sources could include inorganic fertilisers, livestock excreta, or more recently biosolids. The presence of faecal indicator microorganisms has been widely used to identify the presence of faeces, however, these methods cannot distinguish between human and animals samples. This study investigated PCR amplification as a molecular method to distinguish biosolids from livestock faeces of biosolids, cattle, sheep, poultry and kangaroo. This was achieved using published priming sequences and restriction site profiling of amplified DNA across the 16S rRNA gene of anaerobic gastrointestinal bacteria Bacteroides spp and Bifidobacteria spp. Preliminary investigation showed that of the three Bacteroides spp primer pairs investigated, two were useful for cow faecal material; though at lower annealing temperatures were also applicable to biosolids and sheep faecal material. The third primer pair was specific only for biosolids. All three primer pairs were unable to PCR-amplify Bacteroides spp sequences in faecal material of kangaroo. Of the three Bifidobacteria spp primer pairs, one was useful for sheep faecal material; though at lower annealing temperature was also applicable to biosolids and cow and kangaroo faecal material. The Bifidobacterium angulatum specific primer pair enabled the PCR detection of anaerobes only in biosolids and faecal material of kangaroo. The third, a Bifidobacterium catenulatum specific primer pair was suitable for faecal material of cow and at lower annealing temperatures was also applicable to the sample from sheep. Varying degrees of success were observed in faecal material from other animals. Generally, biosolids tested positive for Bacteroides and Bfidobacteria with all primers except for those specific for B. angulatum. For some primer sets, PCR amplification alone could not differentiate biosolids from other faecal samples. The serial dilution of water contaminated by a range of livestock excreta and biosolids is being examined further to enable the sensitivity of this method to be applied in the field

Bias in the Workplace: Consistent Evidence of Sexual Orientation and Gender Identity Discrimination 1998-2008

This article summarizes social science data published during the past decade documenting discrimination against lesbian, gay, bisexual, and transgender (LGBT) people in employment. Over the last ten years, many researchers have conducted studies to find out whether LGBT people face sexual orientation discrimination in the workplace. These studies include surveys of LGBT individuals\u27 workplace experiences, wage comparisons between lesbian, gay, and bisexual (LGB) and heterosexual persons, analyses of discrimination complaints filed with administrative agencies, and testing studies and controlled experiments

Identification of cardiotoxicity related to non-small cell lung cancer (NSCLC) treatments: A systematic review

© 2023 Chan, Khatib, Webley, Layton and Salek. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). https://creativecommons.org/licenses/by/4.0/Introduction: In the last few decades, there has been a rapid development in cancer therapies and improved detection strategies, hence the death rates caused by cancer have decreased. However, it has been reported that cardiovascular disease has become the second leading cause of long-term morbidity and fatality among cancer survivors. Cardiotoxicity from anticancer drugs affects the heart’s function and structure and can occur during any stage of the cancer treatments, which leads to the development of cardiovascular disease. Objectives: To investigate the association between anticancer drugs for non-small cell lung cancer (NSCLC) and cardiotoxicity as to whether: different classes of anticancer drugs demonstrate different cardiotoxicity potentials; different dosages of the same drug in initial treatment affect the degree of cardiotoxicity; and accumulated dosage and/or duration of treatments affect the degree of cardiotoxicity. Methods: This systematic review included studies involving patients over 18 years old with NSCLC and excluded studies in which patients’ treatments involve radiotherapy only. Electronic databases and registers including Cochrane Library, National Cancer Institute (NCI) Database, PubMed, Scopus, Web of Science, ClinicalTrials.gov and the European Union Clinical Trials Register were systematically searched from the earliest available date up until November 2020. A full version protocol of this systematic review (CRD42020191760) had been published on PROSPERO. Results: A total of 1785 records were identified using specific search terms through the databases and registers; 74 eligible studies were included for data extraction. Based on data extracted from the included studies, anticancer drugs for NSCLC that are associated with cardiovascular events include bevacizumab, carboplatin, cisplatin, crizotinib, docetaxel, erlotinib, gemcitabine and paclitaxel. Hypertension was the most reported cardiotoxicity as 30 studies documented this cardiovascular adverse event. Other reported treatment-related cardiotoxicities include arrhythmias, atrial fibrillation, bradycardia, cardiac arrest, cardiac failure, coronary artery disease, heart failure, ischemia, left ventricular dysfunction, myocardial infarction, palpitations, and tachycardia. Conclusion: The findings of this systematic review have provided a better understanding of the possible association between cardiotoxicities and anticancer drugs for NSCLC. Whilst variation is observed across different drug classes, the lack of information available on cardiac monitoring can result in underestimation of this association. Systematic Review Registration: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42020191760, identifier PROSPERO CRD42020191760.Peer reviewe