Formation of 3-dimensional gold, copper and palladium microelectrode arrays for enhanced electrochemical sensing applications

Microelectrodes offer higher current density and lower ohmic drop due to increased radial diffusion. They are beneficial for electroanalytical applications, particularly for the detection of analytes at trace concentrations. Microelectrodes can be fabricated as arrays to improve the current response, but are presently only commercially available with gold or platinum electrode surfaces, thus limiting the sensing of analytes that are more electroactive on other surfaces. In this work, gold (Au), copper (Cu), and palladium (Pd) are electrodeposited at two different potentials into the recessed holes of commercial microelectrode arrays to produce 3-dimensional (3D) spiky, dendritic or coral-like structures. The rough fractal structures that are produced afford enhanced electroactive surface area and increased radial diffusion due to the 3D nature, which drastically improves the sensitivity. 2,4,6-trinitrotoluene (TNT), carbon dioxide gas (CO2), and hydrogen gas (H2) were chosen as model analytes in room temperature ionic liquid solvents, to demonstrate improvements in the sensitivity of the modified microelectrode arrays, and, in some cases (e.g., for CO2 and H2), enhancements in the electrocatalytic ability. With the deposition of different materials, we have demonstrated enhanced sensitivity and electrocatalytic behaviour towards the chosen analytes

THE CHALLENEGE OF NEW APPROACHES IN BIOMECHANICS

The target of our biomechanical research is to analyze the mechanics of motion, focusing especially on the behavior of the muscle-tendon complex during dynamic human movements. In our quest to better understand human motion, we have developed the several research methodologies. In the keynote lecture, I will discuss some of the techniques we have used and what we have learned from them. Specifically I will focus on the following: 1. Ultrasonography 2. Computer Simulation 3. Optical vs Inertial Sensor Analysis

Biomechanical analysis of the relation between movement time and joint moment development during a sit-to-stand task

<p>Abstract</p> <p>Background</p> <p>Slowness of movement is a factor that may cause a decrease of quality of daily life. Mobility in the elderly and people with movement impairments may be improved by increasing the quickness of fundamental locomotor tasks. Because it has not been revealed how much muscle strength is required to improve quickness, the purpose of this study was to reveal the relation between movement time and the required muscle strength in a sit to stand (STS) task. Previous research found that the sum of the peak hip and knee joint moments was relatively invariant throughout a range of movement patterns (Yoshioka et al., 2007, Biomedical Engineering Online 6:26). The sum of the peak hip and knee joint moment is an appropriate index to evaluate the muscle strength required for an STS task, since the effect of the movement pattern variation can be reduced, that is, the results can be evaluated purely from the viewpoint of the movement times. Therefore, the sum of the peak hip and knee joint moment was used as the index to indicate the required muscle strength.</p> <p>Methods</p> <p>Experimental kinematics data were collected from 11 subjects. The time at which the vertical position of the right shoulder fell outside three standard deviations of the vertical positions during the static initial posture was regarded as the start time. The time at which the vertical position fell within three standard deviations of the vertical positions during static upright standing posture was regarded as the finish time. Each movement time of the experimental movements was linearly lengthened and shortened through post-processing. Combining the experimental procedure and the post-processing, movements having various movement patterns and a wide range of movement times were obtained. The joint moment and the static and inertial components of the joint moment were calculated with an inverse dynamics method. The static component reflects the gravitational and/or external forces, while the inertial component reflects the acceleration of the body.</p> <p>Results</p> <p>The quantitative relation between the movement time and the sum of the peak hip and knee joint moments were obtained. As the STS movement time increased, the joint moments decreased exponentially and converged to the static component (1.51 ~ 1.54 N.m/kg). When the movement time was the longest (movement time: 7.0 seconds), the joint moments (1.57 N.m/kg) closely corresponded to the minimum of 1.53 N.m/kg as reported by Yoshioka et al..</p> <p>Conclusion</p> <p>The key findings of this study are as follows. (1) The minimum required joint moment for an STS task is essentially equivalent to the static component of the joint moment. (2) For fast and moderate speed movements (less than 2.5 seconds), joint moments increased exponentially as the movement speed increased. (3) For slow movements greater than 2.5 seconds, the joint moments were relatively constant. The results of this STS research has practical applications, especially in rehabilitations and exercise prescription where improved movement time is an intended target, since the required muscle strength can be quantitatively estimated.</p

INVESTIGATING THE SEATED DOUBLE POLING CYCLE: IDENTIFYING BASELINE MEASURES FOR THE PREPARATION PHASE

The purpose of this study was to identify baseline measures (BM) for the preparation phase (PREP) within the linear stroking cycle for the sport of sledge hockey. The addition of this phase to seated double poling is unclear biomechanically; full arm extension to pick-plant. A validated solid-static prototype mimicking the average single-armed adult male with dynamic shoulder joint was used to determine BM in 3 dimensions and initial pick-impact forces (GRF). Results indicated that average peak GRF occurred prior to 5.0x10-3s post initial contact; Fy=179N, Fz=515N and Fx=573N. Evidence indicated PREP should initiate slightly below the horizon in order to produce the greatest non-contracting force for sledge propulsion. Isolated data provides insight to the biomechanics of the dynamic limb within PREP assisting with its importance to the complete cycle

Apps-olutely fabulous? - The quality of PFMT smartphone app content and design rated using the Mobile App Rating Scale, Behaviour Change Taxonomy, and guidance for exercise prescription

This is the author accepted manuscript. The final version is available from Wiley via the DOI in this recordICS 2019: International Continence Society 49th Annual Meeting, 3-6 September 2019, Gothenburg, SwedenDunedin School of MedicineNational Institute for Health Research (NIHR

Goal setting and strategies to enhance goal pursuit in adult rehabilitation: summary of a Cochrane systematic review and meta-analysis

This is the author proof version of an article accepted for publication in European Journal of Physical and Rehabilitation Medicine 2016.Final version available from the publisher.This paper is based on a Cochrane Review published in the Cochrane Database of Systematic Reviews (CDSR) 2015, Issue 7, Art. No.: CD009727, DOI: 10.1002/14651858 (see www.thecochranelibrary.com for information?Article first published online: January 15, 2016.INTRODUCTION: Goal setting is considered an essential part of rehabilitation, but approaches to goal setting vary with no consensus regarding the best approach. The aim of this systematic review and meta-analysis was to assess the effects of goal setting and strategies to enhance the pursuit of goals on improving outcomes in adult rehabilitation. EVIDENCE ACQUISITION: We searched CENTRAL, MEDLINE, EMBASE, four other databases and three trial registries for randomized control trials (RCTs), cluster RCTs, or quasi-RCTs published before December 2013. Two reviewers independently screened all search results, then critically appraised and extracted data on all included studies. We identified 39 trials, which differed in clinical context, participant populations, research question related to goal use, and outcomes measured. Eighteen studies compared goal setting, with or without strategies to enhance goal pursuit, to no goal setting. EVIDENCE SYNTHESIS: These 18 studies provided very low-quality evidence for a moderate effect size that any type of goal setting is better than no goal setting for improving health-related quality of life or self-reported emotional status (N.=446, standard mean difference [SMD]=0.53, 95% confidence interval [CI]: 0.17 to 0.88), and very low-quality evidence of a large effect size for self-efficacy (N.=108, SMD=1.07, 95% CI: 0.64 to 1.49). Fourteen studies compared a structured approach to goal setting to “usual care” goal setting, where some goals may have been set but no structured approach was followed. These studies provided very low-quality evidence for a small effect size that more structured goal setting results in higher patient self-efficacy (N.=134, SMD=0.37, 95% CI: 0.02 to 0.71). No conclusive evidence was found to support the notion that goal setting, or structured goal setting in comparison to “usual care” goal setting, changes outcomes for patients for measures of participation, activity, or engagement in rehabilitation programs. CONCLUSIONS: This review found a large and increasing amount of research being conducted on goal setting in rehabilitation. However, problems with study design and diversity in methods used means the quality of evidence to support estimated effect sizes is poor. Further research is highly likely to change reported estimates of effect size arising from goal setting in rehabilitation.SD’s position at the University of Exeter Medical School is supported by the National Institute for Health Research (NIHR) Collaboration for Leadership in Applied Health Research and Care South West Peninsula at the Royal Devon and Exeter NHS Foundation Trust. The views expressed are those of the author(s) and not necessarily those of the National Health Service (NHS), the NIHR or the Department of Health

Goal setting and strategies to enhance goal pursuit for adults with acquired disability participating in rehabilitation.

Published onlineJournal ArticleMeta-AnalysisResearch Support, Non-U.S. Gov'tReviewBACKGROUND: Goal setting is considered a key component of rehabilitation for adults with acquired disability, yet there is little consensus regarding the best strategies for undertaking goal setting and in which clinical contexts. It has also been unclear what effect, if any, goal setting has on health outcomes after rehabilitation. OBJECTIVES: To assess the effects of goal setting and strategies to enhance the pursuit of goals (i.e. how goals and progress towards goals are communicated, used, or shared) on improving health outcomes in adults with acquired disability participating in rehabilitation. SEARCH METHODS: We searched CENTRAL, MEDLINE, EMBASE, four other databases and three trials registers to December 2013, together with reference checking, citation searching and contact with study authors to identify additional studies. We did not impose any language or date restrictions. SELECTION CRITERIA: Randomised controlled trials (RCTs), cluster-RCTs and quasi-RCTs evaluating the effects of goal setting or strategies to enhance goal pursuit in the context of adult rehabilitation for acquired disability. DATA COLLECTION AND ANALYSIS: Two authors independently reviewed search results for inclusion. Grey literature searches were conducted and reviewed by a single author. Two authors independently extracted data and assessed risk of bias for included studies. We contacted study authors for additional information. MAIN RESULTS: We included 39 studies (27 RCTs, 6 cluster-RCTs, and 6 quasi-RCTs) involving 2846 participants in total. Studies ranged widely regarding clinical context and participants' primary health conditions. The most common health conditions included musculoskeletal disorders, brain injury, chronic pain, mental health conditions, and cardiovascular disease.Eighteen studies compared goal setting, with or without strategies to enhance goal pursuit, to no goal setting. These studies provide very low quality evidence that including any type of goal setting in the practice of adult rehabilitation is better than no goal setting for health-related quality of life or self-reported emotional status (8 studies; 446 participants; standardised mean difference (SMD) 0.53, 95% confidence interval (CI) 0.17 to 0.88, indicative of a moderate effect size) and self-efficacy (3 studies; 108 participants; SMD 1.07, 95% CI 0.64 to 1.49, indicative of a moderate to large effect size). The evidence is inconclusive regarding whether goal setting results in improvements in social participation or activity levels, body structure or function, or levels of patient engagement in the rehabilitation process. Insufficient data are available to determine whether or not goal setting is associated with more or fewer adverse events compared to no goal setting.Fourteen studies compared structured goal setting approaches, with or without strategies to enhance goal pursuit, to 'usual care' that may have involved some goal setting but where no structured approach was followed. These studies provide very low quality evidence that more structured goal setting results in higher patient self-efficacy (2 studies; 134 participants; SMD 0.37, 95% CI 0.02 to 0.71, indicative of a small effect size) and low quality evidence for greater satisfaction with service delivery (5 studies; 309 participants; SMD 0.33, 95% CI 0.10 to 0.56, indicative of a small effect size). The evidence was inconclusive regarding whether more structured goal setting approaches result in higher health-related quality of life or self-reported emotional status, social participation, activity levels, or improvements in body structure or function. Three studies in this group reported on adverse events (death, re-hospitalisation, or worsening symptoms), but insufficient data are available to determine whether structured goal setting is associated with more or fewer adverse events than usual care.A moderate degree of heterogeneity was observed in outcomes across all studies, but an insufficient number of studies was available to permit subgroup analysis to explore the reasons for this heterogeneity. The review also considers studies which investigate the effects of different approaches to enhancing goal pursuit, and studies which investigate different structured goal setting approaches. It also reports on secondary outcomes including goal attainment and healthcare utilisation. AUTHORS' CONCLUSIONS: There is some very low quality evidence that goal setting may improve some outcomes for adults receiving rehabilitation for acquired disability. The best of this evidence appears to favour positive effects for psychosocial outcomes (i.e. health-related quality of life, emotional status, and self-efficacy) rather than physical ones. Due to study limitations, there is considerable uncertainty regarding these effects however, and further research is highly likely to change reported estimates of effect

Qualitative Studies Linked to Trials of Complex Interventions: what does case study methodology have to offer

PosterOutput Type: Poste

“Are you doing your pelvic floors?” An ethnographic exploration of discussions between women and health professionals about pelvic floor muscle exercises during pregnancy

This is the author accepted manuscript. The final version is available from Wiley via the DOI in this recordICS 2019: International Continence Society 49th Annual Meeting, 3-6 September 2019, Gothenburg, SwedenNational Institute for Health Research (NIHR

Marshall University Music Department Presents Baroque Fever!

https://mds.marshall.edu/music_perf/1705/thumbnail.jp