1,264 research outputs found
Calculation of the Z+jet cross section including transverse momenta of initial partons
We perform calculations of Z+jet cross-section taking into account the
transverse momenta of the initial partons. Transverse Momentum Dependent (TMD)
parton densities obtained with the Parton Branching method are used and higher
order corrections are included via TMD parton showers in the initial state. The
predictions are compared to measurements of forward Z+jet production of the
LHCb collaboration at TeV. We show that the results obtained in
kT-factorization are in good agreement with results obtained from a NLO
calculation matched with traditional parton showers. We also demonstrate that
in the forward rapidity region, kT-factorization and hybrid factorization
predictions agree with each other.Comment: 16 pages, 8 figure
Fluctuating local moments, itinerant electrons and the magnetocaloric effect: the compositional hypersensitivity of FeRh
We describe an ab-initio Disordered Local Moment Theory for materials with
quenched static compositional disorder traversing first order magnetic phase
transitions. It accounts quantitatively for metamagnetic changes and the
magnetocaloric effect. For perfect stoichiometric B2-ordered FeRh, we calculate
the transition temperature of the ferromagnetic-antiferromagnetic transition to
be 495K and a maximum isothermal entropy change in 2 Tesla of J~K~kg. A large (40\%) component of is
electronic. The transition results from a fine balance of competing electronic
effects which is disturbed by small compositional changes - e.g. swapping just
2\% Fe of `defects' onto the Rh sublattice makes drop by 290K. This
hypersensitivity explains the narrow compositional range of the transition and
impurity doping effects.Comment: 11 pages, 4 figure
Study of non-collinear parton dynamics in the prompt photon photoproduction at HERA
We investigate the prompt photon photoproduction at HERA within the framework
of kt-factorization QCD approach. Our consideration is based on the off-shell
matrix elements for the underlying partonic subprocesses. The unintegrated
parton densities in a proton and in a photon are determined using the
Kimber-Martin-Ryskin (KMR) prescription. Additionally, we use the CCFM-evolved
unintegrated gluon as well as valence and sea quark distributions in a proton.
A conservative error analisys is performed. Both inclusive and associated with
the hadronic jet production rates are investigated. The theoretical results are
compared with the recent experimental data taken by the H1 and ZEUS
collaborations. We study also the specific kinematical properties of the
photon-jet system which are strongly sensitive to the transverse momentum of
incoming partons. Using the KMR scheme, the contribution from the quarks
emerging from the earlier steps of the parton evolution is estimated and found
to be of 15 - 20 approximately.Comment: 22 pages, 13 figures, 2 tabl
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Designing Robust Monetary Policy Using Prediction Pools
How should a forward-looking policy maker conduct monetary policy when she has a finite set of models at her disposal, none of which are believed to be the true data generating process? In our approach, the policy makerfirst assigns weights to models based on relative forecasting performance rather than in-sample fit, consistent with her forward-looking objective. These weights are then used to solve a policy design prob-
lem that selects the optimized Taylor-type interest-rate rule that is robust to model uncertainty across a set of well-established DSGE models with and without financial frictions. We find that the choice of weights has a significant impact on the robust optimized rule which is more inertial and aggressive than either the non-robust single model counterparts or the optimal robust rule based on backward-looking weights as
in the common alternative Bayesian Model Averaging. Importantly, we show that a price-level rule has excellent welfare and robustness properties, and therefore should be viewed as a key instrument for policy makers facing uncertainty over the nature of
financial frictions
Relaxation paths for single modes of vibrations in isolated molecules
A numerical simulation of vibrational excitation of molecules was devised,
and used to excite computational models of common molecules into a prescribed,
pure, normal vibration mode in the ground electronic state, with varying,
controlable energy content. The redistribution of this energy (either
non-chaotic or irreversible IVR) within the isolated, free molecule is then
followed in time with a view to determining the coupling strength between
modes. This work was triggered by the need to predict the general characters of
the infrared spectra to be expected from molecules in interstellar space, after
being excited by photon absorption or reaction with a radical. It is found that
IVR from a pure normal mode is very "restricted" indeed at energy contents of
one mode quantum or so. However, as this is increased, or when the excitation
is localized, our approach allows us to isolate, describe and quantify a number
of interesting phenomena, known to chemists and in non-linear mechanics, but
difficult to demonstrate experimentally: frequency dragging, mode locking or
quenching or, still, instability near a potential surface crossing, the first
step to generalized chaos as the energy content per mode is increased.Comment: 25 pages, 15 figures; accepted by J. Atom. Phys.
Motif affinity and mass spectrometry proteomic approach for the discovery of cellular AMPK targets: identification of mitochondrial fission factor as a new AMPK substrate
AMP-activated protein kinase (AMPK) is a key cellular energy sensor and regulator of metabolic homeostasis. Although it is best known for its effects on carbohydrate and lipid metabolism, AMPK is implicated in diverse cellular processes, including mitochondrial biogenesis, autophagy, and cell growth and proliferation. To further our understanding of energy homeostasis through AMPK-dependent processes, the design and application of approaches to identify and characterise novel AMPK substrates are invaluable. Here, we report an affinity proteomicstrategy for the discovery and validation of AMPK targets using an antibody to isolate proteins containing the phospho-AMPK substrate recognition motif from hepatocytes that had been treated with pharmacological AMPK activators. We identified 57 proteins that were uniquely enriched in the activator-treated hepatocytes, but were absent in hepatocytes lacking AMPK. We focused on two candidates, cingulin and mitochondrial fission factor (MFF), and further characterised/validated them as AMPK-dependent targets by immunoblotting with phosphorylation site-specific antibodies. A small-molecule AMPK activator caused transient phosphorylation of endogenous cingulin at S137 in intestinal Caco2 cells. Multiple splice-variants of MFF appear to express in hepatocytes and we identified a common AMPK-dependent phospho-site (S129) in all the 3 predominant variants spanning the mass range and a short variant-specific site (S146). Collectively, our proteomic-based approach using a phospho-AMPK substrate antibody in combination with genetic models and selective AMPK activators will provide a powerful and reliable platform for identifying novel AMPK-dependent cellular targets
The CCFM Monte Carlo generator CASCADE 2.2.0
CASCADE is a full hadron level Monte Carlo event generator for ep, \gamma p
and p\bar{p} and pp processes, which uses the CCFM evolution equation for the
initial state cascade in a backward evolution approach supplemented with off -
shell matrix elements for the hard scattering. A detailed program description
is given, with emphasis on parameters the user wants to change and variables
which completely specify the generated events
Determining the 7Li(n,gamma) cross section via Coulomb dissociation of 8Li
The applicability of Coulomb dissociation reactions to determine the cross
section for the inverse neutron capture reaction was explored using the
reaction 8Li(gamma,n)7Li. A 69.5 MeV/nucleon 8Li beam was incident on a Pb
target, and the outgoing neutron and 7Li nucleus were measured in coincidence.
The deduced (n,gamma) excitation function is consistent with data for the
direct capture reaction 7Li(n,gamma)8Li and with low-energy effective field
theory calculations.Comment: Accepted for publication in Phys. Rev.
Evaluation of optical coherence tomography findings in age-related macular degeneration: a reproducibility study of two independent reading centres
International audienceBackground/aims : To determine the reproducibility among readers of two independent certified centers, the Vienna Reading Center (VRC) and the University of Wisconsin-Madison Reading Center (UW-FPRC) for OCT images in age-related macular degeneration (AMD). Methods : Fast macular thickness scans and 6 mm cross hair scans were obtained from 100 eyes with all subtypes of AMD using Stratus OCT. Consensus readings were performed by two certified OCT readers of each Reading Center using their grading protocol. Common variables of both grading protocols, such as presence of cystoid spaces, subretinal fluid, vitreomacular traction and retinal pigment epithelial detachment were compared using kappa statistics. In addition, the intraclass correlation coefficient (ICC) was calculated for center point thickness (CPT) of values remeasured manually in the presence of alignment errors. Results : The reproducibility was dependent on the variable measured with a kappa value of 0.81 for the presence of cystoid spaces, 0.78 for the presence of subretinal fluid and 0.795 for the presence of vitreomacular traction. The lowest reproducibility was found for the presence of retinal pigment epithelial detachment with a kappa value of 0.51. The CPT was remeasured in 29 out of 100 scans at both sites with an ICC of the remeasured thicknesses of 0.92. Conclusion : OCT scan data are crucial in monitoring treatment efficacy in AMD clinical trials. For comparison of results obtained by different Reading Centers, the inter-Reading Center reproducibility is essential. Although the reproducibility is generally high, the reliability depends on the selected morphological parameters
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