Vortex Effects for Canard-wing Configurations at High Angles of Attack in Subsonic Flow

A fully three-dimensional subsonic panel method that can handle arbitrary shed vortex wakes is used to compute the nonlinear forces and moments on simple canard-wing configurations. The lifting surfaces and wakes are represented by doublet panels. The Mangler-Smith theory is used to provide an initial estimate for the vortex sheet shed from the leading edge. The trailing-edge wake and the leading-edge wake downstream of the trailing edge are assumed to be straight and leave the trailing edge at an angle of alpha/2. Results indicate good agreement with experimental data up to 40 degs angle of attack

Using Electronic Drug Monitor Feedback to Improve Adherence to Antiretroviral Therapy Among HIV-Positive Patients in China

Effective antiretroviral therapy (ART) requires excellent adherence. Little is known about how to improve ART adherence in many HIV/AIDS-affected countries, including China. We therefore assessed an adherence intervention among HIV-positive patients in southwestern China. Eighty subjects were enrolled and monitored for 6 months. Sixty-eight remaining subjects were randomized to intervention/control arms. In months 7–12, intervention subjects were counseled using EDM feedback; controls continued with standard of care. Among randomized subjects, mean adherence and CD4 count were 86.8 vs. 83.8% and 297 vs. 357 cells/μl in intervention vs. control subjects, respectively. At month 12, among 64 subjects who completed the trial, mean adherence had risen significantly among intervention subjects to 96.5% but remained unchanged in controls. Mean CD4 count rose by 90 cells/μl and declined by 9 cells/μl among intervention and control subjects, respectively. EDM feedback as a counseling tool appears promising for management of HIV and other chronic diseases.Boston University and the Office of Health and Nutrition of the United States Agency for International Development (GHS-A-00-03-00030-00); World Health Organization; United States Centers for Disease Control; National Institutes of Health, National Institute of Allergy and Infectious Diseases (K23 AI 62208); Mid-Career Mentoring Award (K24 RR020300

Calculating the Sun\u27s Photospheric Temperature, an Undergraduate Physics Laboratory

We provide physics students and teachers with a simple technique for measuring the solar spectrum and a method for analyzing that spectrum through popular computer software. We discuss modern physics concepts related to blackbody radiation while modeling the sun\u27s spectrum to determine the temperature of the sun\u27s photosphere. We provide a reliable method to determine the sun\u27s photospheric temperature with a typical error of less than 10%, primarily dependent on atmospheric conditions. The focus of this work is on data analysis, not acquisition

Measurement of Solar Spectral Irradiance and Surface Ozone at Carrollton, Georgia, USA, During the Great American Eclipse on 21 August 2017

Measurements conducted at the University of West Georgia, Carrollton, Georgia, during the time of the solar eclipse of 21st August 2017 demonstrated that the integrated spectral irradiance in defined wavelength ranges in the ultraviolet and visible calculated as a fraction of the total irradiance reached a minimum at maximum obscuration of the Sun, whereas in an infrared range it was maximum. The method of analysis adopted supports the view that the changes in spectral irradiance during highly obscured partial phases is a consequence of limb darkening. In a surface ozone measurement, a minimum in ozone concentration occurred 30 +_ minutes after the instant of maximum obscuration. The observation is explained as a combined effects of change in reaction rates of photochemical generation and degradation of ozone

RF Exposure Analysis for Multiple Wi-Fi Devices In Enclosed Environment

Wi-Fi devices operated inside a metallic enclosure have been investigation in the recent years. A motivation for this study is to investigate wave propagation inside an enclosed environment such as elevator, car, aircraft, and spacecraft. There are performances and safety concerned that when the RF transmitters are used in the metallic enclosed environments. In this paper, the field distributions inside a confined room were investigated with multiple portable Wi-Fi devices. Computer simulations were performed using the rigorous computational electromagnetics (CEM). The method of moments (MoM) was used to model the mutual coupling among antennas. The geometrical theory of diffraction (GTD) was applied for the multiple reflections off the ground and walls. The prediction of the field distribution inside such environment is useful for the planning and deployment of a wireless radio and sensor system. Factors that affect the field strengths and distributions of radio waves in confined space were analyzed. The results could be used to evaluate the RF exposure safety in confined environment. By comparing the field distributions for various scenarios, it was observed that the Wi-Fi device counts, spacing and relative locations in the room are important factors in such environments. The RF Keep Out Zone (KOZ), where the electric field strengths exceed the permissible RF exposure limit, could be used to assess the RF human exposure compliance. As shown in this study, it s possible to maximize or minimize field intensity in specific area by arranging the Wi-Fi devices as a function of the relative location and spacing in a calculated manner

Cloning, characterization and expression analysis of porcine microRNAs

Background: MicroRNAs (miRNAs) are small ~22-nt regulatory RNAs that can silence target genes, by blocking their protein production or degrading the mRNAs. Pig is an important animal in the agriculture industry because of its utility in the meat production. Besides, pig has tremendous biomedical importance as a model organism because of its closer proximity to humans than the mouse model. Several hundreds of miRNAs have been identified from mammals, humans, mice and rats, but little is known about the miRNA component in the pig genome. Here, we adopted an experimental approach to identify conserved and unique miRNAs and characterize their expression patterns in diverse tissues of pig.Results: By sequencing a small RNA library generated using pooled RNA from the pig heart, liver and thymus; we identified a total of 120 conserved miRNA homologs in pig. Expression analysis of conserved miRNAs in 14 different tissue types revealed heart-specific expression of miR-499 and miR-208 and liver-specific expression of miR-122. Additionally, miR-1 and miR-133 in the heart, miR-181a and miR-142-3p in the thymus, miR-194 in the liver, and miR-143 in the stomach showed the highest levels of expression. miR-22, miR-26b, miR-29c and miR-30c showed ubiquitous expression in diverse tissues. The expression patterns of pig-specific miRNAs also varied among the tissues examined.Conclusion: Identification of 120 miRNAs and determination of the spatial expression patterns of a sub-set of these in the pig is a valuable resource for molecular biologists, breeders, and biomedical investigators interested in post-transcriptional gene regulation in pig and in related mammals, including humans.Peer reviewedBiochemistry and Molecular BiologyAnimal Scienc

The Foot of Homo Naledi

Modern humans are characterized by a highly specialized foot that reflects our obligate bipedalism. Our understanding of hominin foot evolution is, although, hindered by a paucity of well-associated remains. Here we describe the foot of Homo naledi from Dinaledi Chamber, South Africa, using 107 pedal elements, including one nearly-complete adult foot. The H. naledi foot is predominantly modern human-like in morphology and inferred function, with an adducted hallux, an elongated tarsus, and derived ankle and calcaneocuboid joints. In combination, these features indicate a foot well adapted for striding bipedalism. However, the H. naledi foot differs from modern humans in having more curved proximal pedal phalanges, and features suggestive of a reduced medial longitudinal arch. Within the context of primitive features found elsewhere in the skeleton, these findings suggest a unique locomotor repertoire for H. naledi, thus providing further evidence of locomotor diversity within both the hominin clade and the genus Homo

The Foot of \u3cem\u3eHomo naledi\u3c/em\u3e

Modern humans are characterized by a highly specialized foot that reflects our obligate bipedalism. Our understanding of hominin foot evolution is, although, hindered by a paucity of well-associated remains. Here we describe the foot of Homo naledi from Dinaledi Chamber, South Africa, using 107 pedal elements, including one nearly-complete adult foot. The H. naledi foot is predominantly modern human-like in morphology and inferred function, with an adducted hallux, an elongated tarsus, and derived ankle and calcaneocuboid joints. In combination, these features indicate a foot well adapted for striding bipedalism. However, the H. naledi foot differs from modern humans in having more curved proximal pedal phalanges, and features suggestive of a reduced medial longitudinal arch. Within the context of primitive features found elsewhere in the skeleton, these findings suggest a unique locomotor repertoire for H. naledi, thus providing further evidence of locomotor diversity within both the hominin clade and the genus Homo

The foot of Homo naledi

Modern humans are characterized by a highly specialized foot that reflects our obligate bipedalism. Our understanding of hominin foot evolution is, although, hindered by a paucity of well-associated remains. Here we describe the foot of Homo naledi from Dinaledi Chamber, South Africa, using 107 pedal elements, including one nearly-complete adult foot. The H. naledi foot is predominantly modern human-like in morphology and inferred function, with an adducted hallux, an elongated tarsus, and derived ankle and calcaneocuboid joints. In combination, these features indicate a foot well adapted for striding bipedalism. However, the H. naledi foot differs from modern humans in having more curved proximal pedal phalanges, and features suggestive of a reduced medial longitudinal arch. Within the context of primitive features found elsewhere in the skeleton, these findings suggest a unique locomotor repertoire for H. naledi, thus providing further evidence of locomotor diversity within both the hominin clade and the genus Homo