7 research outputs found
The first two centuries of colonial agriculture in the cape colony: A historiographical review∗
- Author
- Arndt E.H.J.
- Atkin M.
- Atkin M.
- Atkin M.
- Atkin M.
- Atmore Antony
- Beyers Coenraad
- Boeseken Anna
- Boeseken Anna
- Boeseken Anna
- Boeseken Anna
- Bredenkamp H.C.
- Bredenkamp H.C.
- Bredenkamp H.C.
- Breitenbach J.J.
- Brenner Robert
- Buirsky A. P.
- Cooper Frederick
- Cooper Frederick
- Cory Sir George
- Davenport T.R.H.
- Davenport T.R.H.
- Davis David Brion
- De Kiewiet C.W.
- De Kiewiet C.W.
- De Wet G.C.
- Donaldson Margaret E.
- Du Plessis A.J.
- Dubow Saul
- Duly L.C.
- Duly L.C.
- Duminy A.H.
- Duvenhage G.D.J.
- Edwards I.E.
- Elphick Richard
- Elphick Richard
- Elphick Richard
- Foucault Michel
- Franken J.L.M.
- Freund William B.
- Freund William B.
- Fryer A.K.
- Gaastra F.S.
- Gailey Harry A.
- Galbraith J.S.
- Genovese Eugene D.
- Geyer A.L.
- Giliomee H.B.
- Giliomee H.B.
- Godee Molsbergen E.C.
- Graham G.S.
- Guelke Leonard
- Guelke Leonard
- Guelke Leonard
- Hancock W.K.
- Hattersley Alan F.
- Hattingh J.L.
- Hengherr E.
- Ignafieff Michael
- Immelman R.F.M.
- Johnstone Frederick
- Johnstone H.J.M.
- Jooste G.J.
- Judges Shirley
- Kallaway Peter
- Kirk T.E.
- Kirk T.E.
- Lamar Howard
- Le Cordeur Basil A.
- Le Cordeur Basil A.
- Leverton B.J.T.
- Lopez R.S.
- MacCrone I.D.
- MacMillan W.M.
- Malherbe V.C.
- Malherbe V.C.
- Malherbe V.C.
- Malherbe V.C.
- Marcus J.S.
- Marks Shula
- Marks Shula
- Marx Karl
- Mitford‐Barberton I.
- Moodie D.
- Moyer Richard A.
- Muller C.F.J.
- Müller A.L.
- Müller A.L.
- Nash M.D.
- Neumark S.D.
- Newton‐King Susan
- Newton‐King Susan
- Norton William
- Patterson Sheila
- Peires J.B.
- Philip John
- Rayner Mary
- Robert Ross
- Robertson H.M.
- Robertson H.M.
- Robertson H.M.
- Ross Robert
- Ross Robert
- Ross Robert
- Ross Robert
- Ross Robert
- Ross Robert
- Ross Robert
- Sachs A.C.
- Saunders C.C.
- Scholtz P.L.
- Scholtz P.L.
- Schreuder J.H.P.
- Shell Robert
- Smith K.W.
- Stopforth J.A.
- Strauss T.
- Sturgis James
- Swart H.L.G.
- Swart H.L.G.
- Temperley Howard
- Theal G. McC.
- Theal G. McC.
- Theal G. McC.
- Thompson E.P.
- Thompson L.M.
- Thorn H.B.
- Trapido Stanley
- Van Arkel D.
- Van Dam Pieter
- van der Merwe P.J.
- van der Merwe P.J.
- van der Merwe P.J.
- van der Walt A.J.H.
- Van Duin Pieter
- Van Rensburg J.I.J.
- Van Zyl D.J.
- Van Zyl D.J.
- Van Zyl D.J.
- Wagenaar E.J.C.
- Wagenaar G.
- Walker E.A.
- Walker E.A.
- Walker E.A.
- Webb A.C.M.
- Wolpe Harold
- Worden N.A.
- Worden N.A.
- Wright John
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
Claiming Cape Town: towards a symbolic interpretation of Khoisan activism and land claims
- Author
- Publication venue
- 'Informa UK Limited'
- Publication date
- 01/01/2016
- Field of study
Current political negotiations in South Africa which explore the possibility of pre-1913 land claims and the recognition of Khoisan traditional authorities have spurred the growth of the “Khoisan revival”: the phenomenon of people identifying as Khoisan and asserting indigenous rights. Based on fieldwork conducted in Cape Town in 2014 and 2015, this paper discusses the motivations and strategies of several Khoisan activists. After outlining the political context of the Khoisan revival, I show how activists make claims and demands through the use of popular imagery and a global indigenous rights discourse. While producing valuable insights, this “strategic essentialist” approach inadequately addresses motivations for claiming land. Based on a discussion of several case studies, I argue that claiming land functions not so much as a means of procuring physical or economic spaces, but as a way for activists to express grievances regarding coloured identity, history and healing. This symbolic interpretation prompts the reconceptualisation of land claims within the restitution paradigm and policy negotiations
Association of Timing of Plasma Transfusion With Adverse Maternal Outcomes in Women With Persistent Postpartum Hemorrhage
- Author
- Adriaanse H.J.
- Akker E.S.A. van den
- Baas M.I.
- Bank C.M.C.
- Beek E. van
- Bijvank B.H.N.
- Bloemenkamp K.W.M.
- Boer B.A. de
- Boer K. de
- Bom J.G. van der
- Borden D.M.R. van der
- Bremer H.A.
- Brons J.T.J.
- Burggraaff J.M.
- Caram-Deelder C.
- Ceelie H.
- Cessie S. le
- Chon H.
- Cikot R.L.M.
- Delemarre F.M.C.
- Diris J.H.C.
- Doesburg-van Kleffens M.
- Dooren I.A. van
- Duijnhoven H.L.P. van
- Dunne F.M. van
- Duvekot H.J.
- Eikenboom J.C.J.
- Engbers P.
- Etten-van Hulst M.J.W. van
- Feitsma H.
- Fouraux M.A.
- Franssen M.T.M.
- Frasa M.A.M.
- Gammeren A.J. van
- Gemund N. van
- Graaf F. van der
- Groot C.J.M. de
- Hackeng C.M.
- Ham D.P. van der
- Hanssen M.J.C.P.
- Hasaart T.H.M.
- Hendriks H.A.
- Henriquez D.D.C.A.
- Henskens Y.M.C.
- Hermsen B.B.J.
- Hmetz G.C.
- Hogenboom S.
- Hooker A.
- Hudig F.
- Huijssoon A.M.G.
- Huisjes A.J.M.
- Jonker N.
- Kabel P.J.
- Kampen C. van
- Keijzer R.H. de
- Kerkhof D.H. van de
- Keuren J.F.W.
- Kleiverda G.
- Klinkspoor H.
- Koehorst S.G.A.
- Kok J.B. de
- Kok M.
- Kok R.D.
- Koopman-van Gemert A.W.M.M.
- Koops A.
- Kortlandt W.
- Langenveld J.
- Leers M.P.G.
- Leyte A.
- Mare A. de
- Martens G.D.M.
- Meekers J.H.
- Meir C.A. van
- Michielse E.C.H.J.
- Mirani-Oostdijk K.P.
- Mostert L.J.
- Oostenveld E.
- Osmanovic N.
- Oudijk M.A.
- Pampus L.C.M. van
- Papatsonis D.N.M.
- Peters D.H.M.
- Ponjee G.A.E.
- Pontesilli M.
- Porath M.M.
- Post M.S.
- Pouwels J.G.J.
- Prinzen L.
- Roelofsen J.M.T.
- Rondeel H.J.M.
- Roosmalen J.J.M. van
- Salm P.C.M. van der
- Scheepers L.H.C.J.
- Schippers D.H.
- Schuitemaker N.E.
- Sikkema J.M.
- Slomp J.
- Smit J.W.
- Snuif-de Lange Y.S.
- So-Osman C.
- Stappen J.J. van der
- Steures P.
- Tax G.H.M.
- TeMpOH-Res Grp
- Treskes M.
- Ulenkate H.J.L.M.
- Unnik G.A. van
- Veen B.S. van der
- Verhagen T.E.M.
- Versendaal H.
- Visschers B.
- Visser H.
- Visser O.
- Vooght K.M.K. de
- Vries M.J. de
- Waard H. de
- Watering L.G. van de
- Weerkamp F.
- Weinans M.J.N.
- Wet H. de
- Wijnen M. van
- Wijngaarden W.J. van
- Wit S.C. de
- Woiski M.D.
- Zwaginga J.J.
- Zwart J.J.
- Publication venue
- 'American Medical Association (AMA)'
- Publication date
- 01/11/2019
- Field of study
IMPORTANCE Early plasma transfusion for women with severe postpartum hemorrhage (PPH) is recommended to prevent coagulopathy. However, there is no comparative, quantitative evidence on the association of early plasma transfusion with maternal outcomes.OBJECTIVE To compare the incidence of adverse maternal outcomes among women who received plasma during the first 60 minutes of persistent PPH vs women who did not receive plasma for similarly severe persistent PPH.DESIGN, SETTING, AND PARTICIPANTS This multicenter cohort study used a consecutive sample of women with persistent PPH, defined as PPH refractory to first-line measures to control bleeding, between January 1, 2011, and January 1, 2013. Time-dependent propensity score matching was used to select women who received plasma during the first 60 minutes of persistent PPH and match each of them with a woman who had shown the same severity and received the same treatment of PPH but who had not received plasma at the moment of matching. Transfusions were not guided by coagulation tests. Statistical analysis was performed from June 2018 to June 2019.EXPOSURES Transfusion of plasma during the first 60 minutes of persistent PPH vs no or later plasma transfusion.MAIN OUTCOMES AND MEASURES Incidence of adverse maternal outcomes, defined as a composite of death, hysterectomy, or arterial embolization.RESULTS This study included 1216 women (mean [SD] age, 31.6 [5.0] years) with persistent PPH, of whom 932 (76.6%) delivered vaginally and 780 (64.1%) had PPH caused by uterine atony. Seven women (0.6%) died because of PPH, 62 women (5.1%) had a hysterectomy, and 159 women (13.1%) had arterial embolizations. Among women who received plasma during the first 60 minutes of persistent PPH, 114 women could be matched with a comparable woman who had not received plasma at the moment of matching. The incidence of adverse maternal outcomes was similar between the women, with adverse outcomes recorded in 24 women (21.2%) who received early plasma transfusion and 23 women (19.9%) who did not receive early plasma transfusion (odds ratio, 1.09; 95% CI, 0.57-2.09). Results of sensitivity analyses were comparable to the primary results.CONCLUSIONS AND RELEVANCE In this cohort study, initiation of plasma transfusion during the first 60 minutes of persistent PPH was not associated with adverse maternal outcomes compared with no or later plasma transfusion, independent of severity of PPH.Research into fetal development and medicin
The release of genetically modified crops into the environment. Part II. Overview of ecological risk assessment
- Author
- Ammann K.
- Ammann K.
- Andersen H.C.
- Andow D.A.
- Anthony J. Conner
- Baker H.G.
- Bardgett R.D.
- Barrett S.C.H.
- Bruce D.
- CBD (Convention on Biological Diversity)
- CBD (Convention on Biological Diversity)
- Christou P.
- Commandeur P.
- Conner A.J.
- Conner A.J.
- Conner A.J.
- Conner A.J.
- Courvalin P.
- Crawley M.J.
- Dale P.J.
- Dale P.J.
- Dale P.J.
- Daniell H.
- De Kathen A.
- de Wet J.M.J.
- de Wet J.M.J.
- Donegan K.K.
- Editorial
- Editorial
- Ehrlich P.R.
- Escher N.
- Fitter A.
- Frietema de Vries F.T.
- Frietema de Vries F.T.
- Fuchs R.L.
- Gay P.
- Glandorf D.C.M.
- Goklany I.M.
- Gotsch N.
- Hardon J.
- Harlan J.R.
- Harlan J.R.
- Harlan J.R.
- Hilbeck A.
- Hilbeck A.
- Hoffmann T.
- James C.
- Jan-Peter Nap
- Jenson N.F.
- Johnson M.T.
- Jouanin L.
- Kaplan S.
- Kareiva P.
- Kasanmoentalib S.
- Keeler K.
- Keeler K.H.
- Kinderlerer J.
- Kuiper H.A.
- Kumin C.M.
- Kunin W.E.
- Landis W.G.
- Leemans R.
- Leisinger K.M.
- Levidow L.
- Levidow L.
- Linder C.R.
- Linder C.R.
- Linder C.R.
- Lorenz M.G.
- Lorenz M.G.
- Lovei G.
- Lozzia G.C.
- Lumkes L.M.
- Lutman P.W.J.
- Malnoe P.
- Malone L.A.
- Malone L.A.
- May R.M.
- May R.M.
- McGaughey W.H.
- McHughen A.
- McNaughton I.H.
- Metz P.L.J.
- NABC (National Agricultural Biotechnology Council)
- Nap J.P.
- Nap J.P.
- OECD (Organisation for Economic Co-operation and Development)
- Oger P.
- Paul W.J.
- Perrins J.
- Phipps R.H.
- Picard-Nizou A.L.
- Purchase I.F.H.
- Rosa E.A.S.
- Roush R.T.
- Savka M.A.
- Schluter K.
- Schuler T.H.
- Sims S.R.
- Slovic P.
- Slovic P.
- Solbrig O.T.
- Stork N. E.
- Tepfer M.
- Torgersen H.
- Torgersen H.
- Travis R. Glare
- Trewavas A.J.
- Wachbroit R.
- Wijnheijmer E.H.M.
- Williamson M.
- Williamson M.
- Wilson E.O.
- Woiwood I.
- Xia J.Y.
- Yu L.
- Publication venue
- 'Wiley'
- Publication date
- Field of study
Molecular Biological Approaches to Environmental Effects on Photosynthesis
- Author
- A. Sen Gupta
- A. Trewavas
- A.C. McCormac
- A.K. Kononowicz
- A.N. Webber
- B.D. McKersie
- B.J. Mazur
- B.M. Parks
- C. Kuhlemeier
- C.B. Michalowski
- C.B. Michalowski
- C.L. Guy
- D. Wagner
- D.A. Fischhoff
- D.M. Vernon
- D.P. Horvath
- E.J. DeRocher
- E.J. Robertson
- E.M. Tobin
- E.S. Coen
- F. Nagy
- G. Neuhaus
- G.-Y. Nie
- G.-Y. Nie
- G.C. Whitelam
- H. Klee
- H. Smith
- H. Smith
- H. Smith
- H. Zhang
- J. Chory
- J. Nickelsen
- J. Sambrook
- J. Sheen
- J.C. Cushman
- J.C. Thomas
- J.C. Thomas
- J.E. Mullet
- J.E. Mullet
- J.R. Wet de
- J.S. Buzby
- J.W. Reed
- K. Aguan
- K. Aguan
- K. D’Halluin
- K. Keegstra
- K. Ohyama
- K. Shinozaki
- K. Yagamuchi-Shinozaki
- L. Catavelli
- L. Wester
- L. Willmitzer
- M. Ahmad
- M. Hahn
- M. Perras
- M.A. Dunn
- M.A. Dunn
- M.A. Dunn
- M.A. Hughes
- M.A. Hughes
- M.L. Sullivan
- N. Murata
- N.J. Goddard
- N.P.A. Huner
- N.R. Baker
- P. Christou
- P. Gulick
- P. Liang
- P. Tavladoraki
- P.J. Green
- P.M. Gilmartin
- R.A. Jefferson
- R.A. Sharrock
- R.B. Flavell
- R.E. Kendrick
- R.K. Hajela
- S. Kurkela
- S. Ramagopal
- S.R. Rodermel
- S.S. Mohapatra
- T. Urao
- V. Vasil
- V. Walbot
- W.B. Cook
- W.C. Taylor
- W.F. Thompson
- X.-W. Deng
- Y.K. Sharma
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2004
- Field of study
The ASOS Surgical Risk Calculator: development and validation of a tool for identifying African surgical patients at risk of severe postoperative complications
- Author
- A. Abd-rouf
- A. Abduljalil
- A. Abdulrahman
- A. Abokris
- A. Abushnaf
- A. Addanfour
- A. Alatresh
- A. Alfari
- A. Alfetore
- A. Algddar
- A. Alghazali
- A. Alhendery Alhendery
- A. Ali
- A. Ali
- A. Alkilani
- A. Alli
- A. Almajbery
- A. Alsayed
- A. Anele
- A. Attia
- A. Basenero
- A. Berhe
- A. Bogoslovskiy
- A. Dasrath
- A. Dodiyi-Manuel
- A. Ehouni
- A. Elmgadmi
- A. Elshikhy
- A. Elwerfelli
- A. Feituri
- A. Gakenia
- A. Ganesh
- A. Garrido Lopez
- A. Ghnain
- A. Hdud
- A. Ibrahim Abdelatif
- A. Issoufou
- A. Jaber
- A. Juwid
- A. Khamajeet
- A. Maharaj
- A. Maharaj
- A. Mallier Peter
- A. Manneh
- A. Mansour
- A. Metali
- A. Mlotshwa
- A. Mohamed
- A. Mohamed
- A. Mohamed
- A. Mohamed
- A. Mohamed
- A. Muturi
- A. Mwale
- A. Nansook
- A. Onyegbule
- A. Prosper
- A. Rabemazava
- A. Sarkin-Pawa
- A. Shubba
- A. Sohoub
- A. Steyn
- A. Swaleh
- A. Tarhuni
- A. Thotharam
- A. Wafa
- A. Wafula
- A. Zidan
- A. Zo
- A.A. Alraheem
- A.A. Altagazi
- A.A. Aribi
- A.A. Eshwehdi
- A.A. Kornilov
- A.A. Munyika
- A.A. Sheshe
- A.A. Yahya
- A.A. Yunus
- A.A.G. Gomati
- A.B. Muhammad
- A.B. Zerihun
- A.C. Castro
- A.D. Aldarrat
- A.D. Maharaj
- A.E.T. Ayebale
- A.F.X. Agaba
- A.G.B. Andriamampionona
- A.G.L. Rocher
- A.H. Harissou
- A.H. Hery
- A.H.N. Rakotoarisoa
- A.H.R. Rakotoarijaona
- A.I. Ibrahim
- A.I. Levin
- A.I. Yahya
- A.J. Szpytko
- A.J. Vermeulen
- A.J.M. Lumbamba
- A.K. Egote
- A.K. Kintu
- A.K. Koledale
- A.L. AL Samateh
- A.L. Samateh
- A.M. Baloyi
- A.M. Elghallal
- A.M. Elghobashy
- A.M. Elzufri
- A.M. Iraya
- A.M. Kilembe
- A.M. Kukembila
- A.M. Macheka
- A.M. Mohamed
- A.M. Ngalala
- A.M. Torborg
- A.N. Kabongo
- A.N.J.D. Alberts
- A.O. Adisa
- A.O. Omigbodun
- A.O. Osinowo
- A.O. Ousseini
- A.O. Usenbo
- A.P. Gatheru
- A.P. Patience
- A.R.W. Mungherera
- A.S. Shkirban
- A.S. Singh
- A.S. Yusuf
- A.S.B. Benamour
- A.S.M. Madsen
- A.T. Robelie
- A.T.M. Masiyambiri
- A.Z. Elzoway
- A.Z. Machowski
- A.Z. Zeiton
- Abdulaziz M. Elkhogia
- Adam Hewitt-Smith
- Adams
- Ahmadou L. Samateh
- Akinyinka O. Omigbodun
- Akwasi Antwi-Kusi
- Al.-A. Amer
- Al.-J. Ahmed
- Alex M. Makupe
- Ambroise Guegni
- Amina. Kalisa
- Anatole Atomabe
- Andrew K.N. Ndonga
- Anthony R. Reed
- Apollo. Basenero
- B. Ahmed
- B. Alsellabi
- B. Chrirangi
- B. Church
- B. Dedekind
- B. Gadi
- B. Githae
- B. Kipng’etich
- B. Kiprop
- B. Lerutla
- B. Ntueba
- B. Rink
- B. Thakoor
- B. Veerasamy
- B.A. Albakosh
- B.A. Dokolwana
- B.B. Afolabi
- B.B. Osinaike
- B.B. Ryabchiy
- B.C. Businge
- B.C. Enicker
- B.E. Bilby
- B.H. Pienaar
- B.J.S. Diedericks
- B.M. Biccard
- B.M. Mabaso
- B.M. Ngari
- B.N. BN Tanjong
- B.N.K. Kaholongo
- B.O. Mofikoya
- B.O. Semo
- B.P. Thomas
- B.S. Sikombe
- B.S.G. Diale
- B.T. Amisi
- Belinda S. Kusel
- Bernard Mbwele
- Beye Seïdina Alioune
- Biccard
- Biccard
- Blaise Tchaou
- Bruce M. Biccard
- Busi Mrara
- C. Bitta
- C. Chalo
- C. Changfoot
- C. Dhege
- C. Houston
- C. Kruse
- C. Lee
- C. Lionnet
- C. Manirimbere
- C. Msadabwe
- C. Nantulu
- C. Ndung’u
- C. Nnaji
- C. Ntoto
- C.A. Blake
- C.A. Roberts
- C.A.G. Smits
- C.H. Basson
- C.J. Bikuelo
- C.J.M. Mawire
- C.L.C. Lubamba
- C.M. Human
- C.M. Mwangi
- C.N. Mwaluka
- C.N. Namata
- C.R. Saaiman
- C.S. Jallow
- C.S. Sendagire
- C.S. Shambare
- C.Z. Zinyemba
- Chaibou M. Sani
- Charles Tchegnonsi
- Chris Cairns
- Christella S. Alphonsus
- Christina Salmina Gordon
- Christopher Y. Matola
- Collins
- Coulibaly Youssouf
- D. Benali
- D. Daliri
- D. Elrafifi
- D. Hugo
- D. Krick
- D. Naidoo
- D. Ndegwa
- D. Ngorora
- D. Ngouane
- D. Roytowski
- D. Tarloff
- D.E. du Plessis
- D.F. Dibwe
- D.G. Giles
- D.H. Imposo
- D.I. Uhuebor
- D.J. Van der Merwe
- D.K. Kabatoro
- D.K. Sanduku
- D.M. Adeleke
- D.M. Linyama
- D.M. Maimane
- D.M. Maluleke
- D.M. Mangoo
- D.M. Munlemvo
- D.M.A. Aurélia
- D.M.A. Randriambololona
- D.O. Ojuka
- D.P. Domoyyeri
- D.R. Bhagwandass
- D.S. Nesengani
- D.S. Sikazwe
- D.V. Manyere
- Daniel Zemenfes Ashebir
- David G. Bishop
- David Lee Skinner
- Dela A. Maiwald
- Devan. Rungan
- Diallo Gangaly
- Diango Djibo Mahamane
- Dolly M. Munlemvo
- Dominique van Dyk
- Doreen M. Mashava
- E. Atito-Narh
- E. Blignaut
- E. Chikumba
- E. Hadia
- E. Horugavye
- E. Loots
- E. Mashoko
- E. Ngatia
- E. Ninise
- E. Salaheddin
- E. Swayeb
- E.A. Alakkari
- E.A. Alzahra
- E.B. Etuk
- E.B. Holford
- E.E. Wynne
- E.F. Post
- E.K. Badianga
- E.K. Makopa
- E.M. Semenya
- E.N. Waweru
- E.O. Enendu
- E.O. Enwerem
- E.O. Ogboli-Nwasor
- E.S. al Shams
- E.S. Namegabe
- E.V. Neluheni
- Edith Djessouho
- El.-Z. Ahmed
- Ernest Nkwabi
- Estie Cloete
- Eugene Zoumenou
- F. Abuhdema
- F. Albert
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- Thiam Souleymane
- Thomas Allaye
- Thuli Biyase
- Tim C. Hardcastle
- Tonya M. Esterhuizen
- Traoré Abdoulaye
- Traoré Ibrahim
- U.V. Jaganath
- Usha Singh
- Ushmaben Patel
- V. Athanse
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- V. Govindasamy
- V. Makhanya
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- V.K. Kusweje
- V.K. Mushangwe
- V.L. Koller
- V.L. Moses
- V.M. Gacii
- V.M. Mtongwe
- V.M.K. Kissoon
- V.N. Nziene
- V.T. Manzini
- Veekash Gobin
- W. Abozaid
- W. Conradie
- W. Kibochi
- W. Kuhn
- W. Mathangani
- W. Njuguna
- W. Rois
- W. Sam-Awortwi
- W.A.G. Simo
- W.A.P. Ras
- W.D. Mbombo
- W.M. du Plessis
- W.M.S. Mbuyi
- W.P. Kuhn
- W.P. Makhaye
- W.V.J. Koperski
- Wong
- Y. Baitchu
- Y. Coulibaly
- Y. le Manach
- Y. Mampangula
- Y. Najm
- Y. Yakubu
- Y.A. Ali
- Y.B. Adamu
- Y.B. Bwambale
- Y.B.M. Freeman
- Y.G. Gandy
- Y.M. Yangazov
- Y.Y. Kutor
- Yannick Le Manach
- Youssouf Coulibaly
- Z. Farina
- Z. Imessaoudene
- Z. Nibe
- Z. Nyatela-Akinrinmade
- Z. Rakhda
- Z.S. Elghazal
- Z.S. Jamal
- Zipporah W.W. Ngumi
- Publication venue
- 'Elsevier BV'
- Publication date
- 17/09/2018
- Field of study
Background:
The African Surgical Outcomes Study (ASOS) showed that surgical patients in Africa have a mortality twice the global average. Existing risk assessment tools are not valid for use in this population because the pattern of risk for poor outcomes differs from high-income countries. The objective of this study was to derive and validate a simple, preoperative risk stratification tool to identify African surgical patients at risk for in-hospital postoperative mortality and severe complications.
Methods:
ASOS was a 7-day prospective cohort study of adult patients undergoing surgery in Africa. The ASOS Surgical Risk Calculator was constructed with a multivariable logistic regression model for the outcome of in-hospital mortality and severe postoperative complications. The following preoperative risk factors were entered into the model; age, sex, smoking status, ASA physical status, preoperative chronic comorbid conditions, indication for surgery, urgency, severity, and type of surgery.
Results:
The model was derived from 8799 patients from 168 African hospitals. The composite outcome of severe postoperative complications and death occurred in 423/8799 (4.8%) patients. The ASOS Surgical Risk Calculator includes the following risk factors: age, ASA physical status, indication for surgery, urgency, severity, and type of surgery. The model showed good discrimination with an area under the receiver operating characteristic curve of 0.805 and good calibration with c-statistic corrected for optimism of 0.784.
Conclusions:
This simple preoperative risk calculator could be used to identify high-risk surgical patients in African hospitals and facilitate increased postoperative surveillance.
© 2018 British Journal of Anaesthesia. Published by Elsevier Ltd. All rights reserved.Medical Research Council of South Africa gran
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