Septo-optic Dysplasia- Case Report

The clinical triad of septo-optic dysplasia (SOD) comprises the absence of the septum pellucidum, congenital optic nerve dysplasia, and multiple endocrine disorders. When any two of these factors are present, the condition is defined as an incomplete form of SOD. The authors report the case of an incomplete form of SOD in a 9-year-old boy with low vision and nystagmus present from birth. The bilateral ophthalmoscopic examination revealed small papillae with double contour images. Magnetic resonance imaging showed hypoplasia of the optic nerve bilaterally, chiasm and absence of the septum pellucidum.674653655De Morsier, G., Études sur les dysraphies cranio-encéphaliques. III. Agénésie du septum pellucidum avec malformation du tractus optique: La dysplasie septo-optique (1956) Schweiz Arch Neurol Psychiatr, 77 (1-2), pp. 267-292. , Texto inglês: [Studies on malformation of cranio-encephalic sutures.III. Agenesis of the septum lucidum with malformation of the optic tractKaplan, S., Grumbach, M.M., Hoyt, W., The syndrome of hypopituitary dwarfism, hypoplasia of optic nerves and malformation of prosencephalon: Report of 6 patients (1970) Pediatr Res, 4, pp. 480-481Lippe, B., Kaplan, S.A., La Franchi, S., Septo-optic dysplasia and maternal age (1979) Lancet, 2 (8133), pp. 92-93Purdy, F., Maternal factors in septo-optic dysplasia (1979) J Pediatr, 95 (4), p. 661Lambert, S.R., Hoyt, C.S., Narahara, M.H., Optic nerve hypoplasia (1987) Surv Ophthalmol, 32 (1), pp. 1-9Davis, G.V., Shock, J.P., Septo-optic dysplasia associated with see-saw nystagmus (1975) Arch Ophthalmol, 93 (2), pp. 137-139Williams, J., Brodsky, M.C., Griebel, M., Glasier, C.M., Caldwell, D., Thomas, P., Septo-optic dysplasia: The clinical insignificance of an absent septum pellucidum (1993) Dev Med Child Neurol, 35 (6), pp. 490-501Willnow, S., Kiess, W., Butenandt, O., Dörr, H.G., Enders, A., Strasser-Vogel, B., Endocrine disorders in septo-optic dysplasia (De Morsier syndrome) - evaluation and follow up of 18 patients (1996) Eur J Pediatr, 155 (3), pp. 179-18

Conjunctival keratoacanthoma

Keratoacanthoma generally occurs on the skin; it is rarely found in the conjunctiva. A case of a 34-year-old woman with a rapidly growing conjunctival mass is reported. The tumor was excised with a safety margin to exclude squamous cell carcinoma. Histopathologically it was crateriform and consistent with atypical keratoacanthoma. There has been no recurrence in 2 years of follow-up. Conjunctival keratoacanthoma is rare; differential diagnosis of conventional squamous cell carcinoma and keratoacanthoma can be difficult. We recommend complete surgical excision and careful follow-up of crateriform squamous proliferations.Ceratoacantoma geralmente ocorre na pele e raramente é encontrado na conjuntiva. Relatamos um caso de uma mulher de 34 anos que apresentou uma massa conjuntival de rápido crescimento. O tumor foi retirado com margem de segurança para excluir carcinoma de células escamosas. Ao exame histopatológico, o tumor apresentou configuração crateriforme, sendo consistente com ceratoacantoma atípico. Não houve recorrência após dois anos de seguimento. Ceratoacantoma conjuntival é uma doença rara. Um diagnóstico diferencial entre carcinoma de células escamosas e ceratoacantoma pode ser difícil. Recomendamos total remoção e seguimento cuidadoso de pacientes com lesões escamosas crateriformes

Disseminated Paracoccidioidomycosis With Chorioretinal Involvement [10]

[No abstract available]19910211023Silva, M.R., Mendes, R.P., Lastória, J.C., Barraviera, B., Marques, M.R., Kamegasawa, A., Paracoccidioidomycosis: Study of six cases with ocular involvement (1988) Mycopathologia, 102 (2), pp. 87-96Ajello, L., Polonelli, L., Imported paracoccidioidomycosis: A public health problem in non-endemic areas (1985) Eur J Epidemiol, 1 (3), pp. 160-165Bonomo, P.P., Belfort Jr., R., Tsunechiro, Jy., Filho, O.G., Choroidal granuloma caused by Paracoccidioides brasiliensis. A clinical and angiographic study (1982) Mycopathologia, 77 (1), pp. 37-41Negroni, R., Paracoccidioidomycosis (South American blastomycosis, Lutz's mycosis) (1993) Int J Dermatol, 32 (12), pp. 847-859Manns, B.J., Baylis, B.W., Urbanski, S.J., Gibb, A.P., Rabin, H.R., Paracoccidioidomycosis: Case report and review (1996) Clin Infect Dis, 23 (5), pp. 1026-1032Belfort Jr., R., Fishman, D.O., de Camargo, Z.P., Almada, A., Paracoccidioidomycosis with palpebral and conjunctival involvement (1975) Mycopathologia, 56 (1), pp. 21-24Arruda, W.O., Canto, M.A., Loddo, G., Rebuffi, V.F., Cardoso, M.A., Ocular paracoccidioidomycosis. Report of a case with posterior chorioretinitis (1986) Rev Inst Med Trop São Paulo, 28 (3), pp. 190-19

Analysis Of Correlation Between Pseudoexfoliation Syndrome And Aneurysm Of The Abdominal Aorta [análise Da Correlação Entre Síndrome De Pseudo-exfoliação E Aneurisma De Aorta Abdominal]

Purpose: To investigate the suggested association between pseudoexfoliation syndrome and aneurysm of the abdominal aorta. Methods: 65 patients recently operated for abdominal aortic aneurysm and 51 controls with peripheral atherosclerosis, without aneurysm, underwent an ophthalmologic examination under pupillary dilatation to detect the presence of pseudoexfoliation syndrome. Results: There were no significant differences regarding mean age and distribution by gender and race between the groups (p > 0.05). Two of 65 patients with aortic aneurysm and one of 51 controls presented pseudoexfoliation syndrome (p = 1.00). Conclusion: The prevalence of pseudoexfoliation syndrome in patients operated for abdominal aortic aneurysm and in patients with peripheral atherosclerosis were similar. This finding does not support the proposed association between pseudoexfoliation syndrome and abdominal aortic aneurysm.673407410Schlötzer-Scherehardt, U., Koca, M.R., Naumann, G.O., Volkholz, H., Pseudoexfoliation syndrome: Ocular manifestation of a systemic disorder? (1992) Arch Ophthalmol, 110, pp. 1752-1756Streeten, B.W., Dark, A.J., Wallace, R.N., Li, Z.Y., Hoepner, J.A., Pseudoexfoliative fibrillopathy in the skin of patients with ocular pseudoexfoliation (1990) Am J Ophthalmol, 110, pp. 490-499Streeten, B.W., Li, Z.Y., Wallace, R.N., Eagle, R.C., Keshgegian, A.A., Pseudoexfoliative fibrillopathy in visceral organs of a patient with pseudoexfoliation syndrome (1992) Arch Ophthalmol, 110, pp. 1757-1762Cursiefen, C., Händel, A., Schönherr, U., Naumman, G.O., Das pseudoexfoliation ssyndrom bei Patienten mit retinaler Venenast-und Zentralvenenthrombose (1997) Klin Monatsbl Augenheilkd, 211, pp. 17-21Cursifen, C., Hammer, T., Kückle, M., Naumann, G.O.H., Schlötzer- Schrehardt, U., Pseudoexfoliation syndrome in eyes with ischemic central retinal vein occlusion. A histopathologic and electron microscopic study (2001) Acta Ophthalmol Scand, 79, pp. 476-478Mitchell, P., Wang, J.J., Smith, W., Association of pseudoexfoliation syndrome with increased vascular risk (1997) Am J Ophthalmol, 124, pp. 685-687Kling, F., Colin, J., Joris, A., Pseudoexfoliation syndrome (PEX): Indicator of increased cardiac and/or vascular risks? [poster] (1999) American Academy Ophthalmology, , Orlando Florida OctoberRitch, R., Exfoliation syndrome: The most common identifiable cause of openangle glaucoma (1994) J Glaucoma, 3, pp. 176-178Ritch, R., Schlötzer-Schrehardt, U., Exfoliation syndrome (2001) Surv Ophthalmol, 45, pp. 265-315Shields, M.B., Glaucomas associated with disorder of the lens (1998) Textbook of Glaucoma, pp. 252-268. , Shields MB. 5 th ed. Baltimore: Williams and WilkinsSchlötzer-Schrehardt, U., Von Der Mark, K., Sakai, Ly., Naumann, G.O., Increased extracellular deposition of fibrillin-1 containing fibrils in pseudoexfoliation syndrome (1997) Invest Ophthalmol Vis Sci, 38, pp. 970-984Schumacher, S., Schlötzer-Scherehardt, U., Martus, P., Lang, W., Naumann, G.O.H., Pseudoexfoliation syndrome and aneurysms of the abdominal aorta (2001) Lancet, 357, pp. 359-360Yüksel, N., Karabas, L., Arslan, A., Demirci, A., Çaglar, Y., Ocular hemodynamics in pseudoexfoliation syndrome and pseudoexfoliation glaucoma (2001) Ophthalmology, 108, pp. 1043-1049Ringvold, A., Pseudoexfoliation and aortic aneurysms (2001) Lancet, 357, pp. 2139-2140Hietanen, J., Soisalon-Soinimen, S., Kivelan, T., Tarkkanen, A., Evaluation the clinical association between exfoliation syndrome and abdominal aortic aneurysm (2002) Acta Ophthalmol Scand, 80, pp. 617-619Urbano, A.P., Freitas, T.G., Arcieri, E.S., Urbano, A.P., Costa, V.P., Avaliação dos tipos de glaucoma no Serviço de Oftalmologia da UNICAMP (2003) Arq Bras Oftalmol, 66, pp. 61-65Ringvold, A., Blika, S., Elsas, T., Guldahl, J., Brevik, T., Hesstvedt, P., The prevalence of pseudoexfoliation in three separate municipalities of Middle-Norway (1987) Acta Ophthalmol, (SUPPL. 182), pp. 17-2