Swimming is never without risk: opening up on learning through activism and research

This article examines my own becoming as Elisabeth and as a researcher. It is about working as a support worker, coaching teams that are trying to realize inclusive education for a child, and my PhD process, which relies on these practices. My intention here is to unfold several aspects, blockages, possibilities, and tensions that can make sense of my messy struggle. The never-ending learning through working with people, listening to their stories, and taking responsibility are important ingredients of my engagement. It is necessary to provide insights and justify my multiple positions to avoid falling into a narcissistic trap. In doing so, I will seek help from Levinas and in concepts of Deleuze and Guattari to (re-)construct my own understanding

An improved vitrification protocol for equine immature oocytes, resulting in a first live foal

Background: The success rate for vitrification of immature equine oocytes is low. Although vitrified-warmed oocytes are able to mature, further embryonic development appears to be compromised. Objectives: The aim of this study was to compare two vitrification protocols, and to examine the effect of the number of layers of cumulus cells surrounding the oocyte during vitrification of immature equine oocytes. Study design: Experimental in vitro and in vivo trials. Methods: Immature equine oocytes were vitrified after a short exposure to high concentrations of cryoprotective agents (CPAs), or a long exposure to lower concentrations of CPAs. In Experiment 1, the maturation of oocytes surrounded by multiple layers of cumulus cells (CC oocytes) and oocytes surrounded by only corona radiata (CR oocytes) was investigated. In Experiment 2, spindle configuration was determined for CR oocytes vitrified using the two vitrification protocols. In Experiment 3, further embryonic development was studied after fertilisation and culture. Embryo transfer was performed in a standard manner. Results: Similar nuclear maturation rates were observed for CR oocytes vitrified using the long exposure and nonvitrified controls. Furthermore, a lower maturation rate was obtained for CC oocytes vitrified with the short exposure compared to control CR oocytes (P = 0.001). Both vitrification protocols resulted in significantly higher rates of aberrant spindle configuration than the control groups (P<0.05). Blastocyst development only occurred in CR oocytes vitrified using the short vitrification protocol, and even though blastocyst rates were significantly lower than in the control group (P<0.001), transfer of five embryos resulted in one healthy foal. Main limitations: The relatively low number of equine oocytes and embryo transfer procedures performed. Conclusions: For vitrification of immature equine oocytes, the use of 1) CR oocytes, 2) a high concentration of CPAs, and 3) a short exposure time may be key factors for maintaining developmental competence

Disability Studies in de Lage Landen

INKIJKEXEMPLAAR - ‘Disability’ gaat in oorsprong terug naar een fenomeen dat ontstaat wanneer iemand met een beperking/stoornis/label op een negatieve manier geconfronteerd wordt met gebouwde, fysieke, sociale, georganiseerde en culturele omgevingen. Dergelijke op zijn minst onaangename confrontaties ontstaan omdat een groot deel van de huidige samenleving gespiegeld wordt aan wat een ‘normaal’ persoon wordt genoemd. Disabilty studies scholars zijn lange tijd blijven hangen in een modellenstrijd. De laatste tijd wordt echter een heel andere discussie gevoerd. Het gaat immers om een complex en relationeel probleem met vele armen. Precies dit geheel wordt in dit boek vanuit diverse invalshoeken geanalyseerd