365 research outputs found
Modality, Potentiality and Contradiction in Quantum Mechanics
In [11], Newton da Costa together with the author of this paper argued in
favor of the possibility to consider quantum superpositions in terms of a
paraconsistent approach. We claimed that, even though most interpretations of
quantum mechanics (QM) attempt to escape contradictions, there are many hints
that indicate it could be worth while to engage in a research of this kind.
Recently, Arenhart and Krause [1, 2, 3] have raised several arguments against
this approach and claimed that, taking into account the square of opposition,
quantum superpositions are better understood in terms of contrariety
propositions rather than contradictory propositions. In [17] we defended the
Paraconsistent Approach to Quantum Superpositions (PAQS) and provided arguments
in favor of its development. In the present paper we attempt to analyze the
meanings of modality, potentiality and contradiction in QM, and provide further
arguments of why the PAQS is better suited, than the Contrariety Approach to
Quantum Superpositions (CAQS) proposed by Arenhart and Krause, to face the
interpretational questions that quantum technology is forcing us to consider.Comment: Published in: New Directions in Paraconsistent Logic, J-Y B\'eziau M.
Chakraborty & S. Dutta (Eds.), Springer, in press. arXiv admin note: text
overlap with arXiv:1404.518
Carnot cycle for an oscillator
Carnot established in 1824 that the efficiency of cyclic engines operating
between a hot bath at absolute temperature and a bath at a lower
temperature cannot exceed . We show that linear
oscillators alternately in contact with hot and cold baths obey this principle
in the quantum as well as in the classical regime. The expression of the work
performed is derived from a simple prescription. Reversible and non-reversible
cycles are illustrated. The paper begins with historical considerations and is
essentially self-contained.Comment: 19 pages, 3 figures, sumitted to European Journal of Physics Changed
content: Fluctuations are considere
Enhancement of feline immunodeficiency virus infection after immunization with envelope glycoprotein subunit vaccines.
Cats were immunized three times with different recombinant feline immunodeficiency virus (FIV) candidate vaccines. Recombinant vaccinia virus (rVV)-expressed envelope glycoprotein with (vGR657) or without (vGR657 x 15) the cleavage site and an FIV envelope bacterial fusion protein (beta-Galactosidase-Env) were incorporated into immune-stimulating complexes or adjuvanted with Quil A. Although all immunized cats developed antibodies against the envelope protein, only the cats vaccinated with the rVV-expressed envelope glycoproteins developed antibodies which neutralized FIV infection of Crandell feline kidney cells. These antibodies failed to neutralize infection of thymocytes with a molecularly cloned homologous FIV. After the third immunization the cats were challenged with homologous FIV. Two weeks after challenge the cell-associated viral load proved to be significantly higher in the cats immunized with vGR657 and vGR657 x 15 than in the other cats. The cats immunized with vGR657 and vGR657 x 15 also developed antibodies against the Gag proteins more rapidly than the cats immunized with beta-Galactosidase-Env or the control cats. This suggested that immunization with rVV-expressed glycoprotein of FIV results in enhanced infectivity of FIV. It was shown that the observed enhancement could be transferred to naive cats with plasma collected at the day of challenge
Insights in a restricted temporary pacemaker strategy in a lean transcatheter aortic valve implantation program
OBJECTIVES: To study the safety and feasibility of a restrictive temporaryâRVâpacemaker use and to evaluate the need for temporary pacemaker insertion for failed left ventricular (LV) pacing ability (no ventricular capture) or occurrence of highâdegree AVâblocks mandating continuous pacing. BACKGROUND: Ventricular pacing remains an essential part of contemporary transcatheter aortic valve implantation (TAVI). A temporaryârightâventricle (RV)âpacemaker lead is the standard approach for transient pacing during TAVI but requires central venous access. METHODS: An observational registry including 672 patients who underwent TAVI between June 2018 and December 2020. Patients received pacing on the wire when necessary, unless there was a highâanticipated risk for conduction disturbances postâTAVI, based on the baselineâECG. The followâup period was 30âdays. RESULTS: A temporaryâRVâpacemaker lead (RVPâcohort) was inserted in 45 patients, pacing on the wire (LVPâcohort) in 488 patients, and no pacing (NoPâcohort) in 139 patients. A bailout temporary pacemaker was implanted in 14 patients (10.1%) in the NoPâcohort and in 24 patients (4.9%) in the LVPâcohort. One patient in the LVPâcohort needed an RVâpacemaker for incomplete ventricular capture. Procedure time was significantly longer in the RVPâcohort (68âmin [IQR 52â88.] vs. 55âmin [IQR 44â72] in NoPâcohort and 55âmin [IQR 43â71] in the LVPâcohort [pâ<â0.005]). Procedural highâdegree AVâblock occurred most often in the RVPâcohort (45% vs. 14% in the LVP and 16% in the NoPâcohort [pââ€â0.001]). Need for new PPI occurred in 47% in the RVPâcohort, versus 20% in the NoPâcohort and 11% in the LVPâcohort (pââ€â0.001). CONCLUSION: A restricted RVâpacemaker strategy is safe and shortens procedure time. The majority of TAVIâprocedures do not require a temporaryâRVâpacemaker
Measurement of mechanical vibrations excited in aluminium resonators by 0.6 GeV electrons
We present measurements of mechanical vibrations induced by 0.6 GeV electrons
impinging on cylindrical and spherical aluminium resonators. To monitor the
amplitude of the resonator's vibrational modes we used piezoelectric ceramic
sensors, calibrated by standard accelerometers. Calculations using the
thermo-acoustic conversion model, agree well with the experimental data, as
demonstrated by the specific variation of the excitation strengths with the
absorbed energy, and with the traversing particles' track positions. For the
first longitudinal mode of the cylindrical resonator we measured a conversion
factor of 7.4 +- 1.4 nm/J, confirming the model value of 10 nm/J. Also, for the
spherical resonator, we found the model values for the L=2 and L=1 mode
amplitudes to be consistent with our measurement. We thus have confirmed the
applicability of the model, and we note that calculations based on the model
have shown that next generation resonant mass gravitational wave detectors can
only be expected to reach their intended ultra high sensitivity if they will be
shielded by an appreciable amount of rock, where a veto detector can reduce the
background of remaining impinging cosmic rays effectively.Comment: Tex-Article with epsfile, 34 pages including 13 figures and 5 tables.
To be published in Rev. Scient. Instr., May 200
Changing haemodynamic status of patients referred for transcatheter aortic valve intervention during the COVID-19 pandemic
The fidelity of dynamic signaling by noisy biomolecular networks
This is the final version of the article. Available from Public Library of Science via the DOI in this record.Cells live in changing, dynamic environments. To understand cellular decision-making, we must therefore understand how fluctuating inputs are processed by noisy biomolecular networks. Here we present a general methodology for analyzing the fidelity with which different statistics of a fluctuating input are represented, or encoded, in the output of a signaling system over time. We identify two orthogonal sources of error that corrupt perfect representation of the signal: dynamical error, which occurs when the network responds on average to other features of the input trajectory as well as to the signal of interest, and mechanistic error, which occurs because biochemical reactions comprising the signaling mechanism are stochastic. Trade-offs between these two errors can determine the system's fidelity. By developing mathematical approaches to derive dynamics conditional on input trajectories we can show, for example, that increased biochemical noise (mechanistic error) can improve fidelity and that both negative and positive feedback degrade fidelity, for standard models of genetic autoregulation. For a group of cells, the fidelity of the collective output exceeds that of an individual cell and negative feedback then typically becomes beneficial. We can also predict the dynamic signal for which a given system has highest fidelity and, conversely, how to modify the network design to maximize fidelity for a given dynamic signal. Our approach is general, has applications to both systems and synthetic biology, and will help underpin studies of cellular behavior in natural, dynamic environments.We acknowledge support from a Medical Research Council and Engineering and Physical Sciences Council funded Fellowship in Biomedical Informatics (CGB) and a Scottish Universities Life Sciences Alliance chair in Systems Biology (PSS). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript
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Detailed Morphology and Structure of an Active Submarine Arc Caldera: Brothers Volcano, Kermadec Arc
A survey of the Brothers caldera volcano (Kermadec arc) with the autonomous underwater vehicle ABE has revealed new details of the morphology and structure of this submarine frontal arc caldera and the geologic setting of its hydrothermal activity. Brothers volcano has formed between major SW-NEâtrending faults within the extensional field of the Havre Trough. Brothers may be unique among known submarine calderas in that it has four active hydrothermal systems, two high-temperature sulfide-depositing sites associated with faulting on the northwestern and western walls (i.e., the NW caldera and W caldera hydrothermal sites, respectively), and gas-rich sites on the summits of the constructional cones that fill most of the southern part of the caldera (i.e., the Upper and Lower cone sites). The 3.0- Ă 3.4-km caldera is well defined by a topographic rim encompassing âŒ320° of its circumference and which lies between the bounds of two outer half-grabenâshaped faults in the northwest and southeast sectors. There is not a morphologically well defined continuous ring fault (at the map resolution), although near-vertical scarps are present discontinuously at the base of sections of the wall. The width of the wall varies from <200 m at its southwest portion to âŒ750 m on its northern section. The widest part of the wall is its northwest sector, which also has the largest documented area of hydrothermal alteration and where sea-floor magnetization is lowest. In addition to primary northwest-southeast elongation and southwest-northeast structures caused by faulting within the regional back-arc strain field, there are also less well developed west-southwestânorth-northeast regional structures intersecting the volcano that is apparent on the ABE bathymetry and at outcrop scale from submersible observations. Asymmetrical trap-doorâstyle caldera collapse is considered a possible mechanism for the formation of the Brothers caldera
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