Engineering Education Periodicals and Proceedings: Increasing Awareness of and Access to the Literature

In the vast realm, of engineering literature there is a set of publications that is often unknown and certainly underutilized: engineering education periodicals and proceedings. These publications can easily be overlooked by engineering faculty, researchers, students, librarians or information professionals, and others who may not be fully aware of their existence or content. There has been a need for a definitive list of such publications for some time. This paper presents an initial list of these hems as the first step to make them more accessible to those in engineering education who may need them. The next step wil1 be to create a descriptive database of these items, briefly detailing their content, stating who publishes them, indicating what indexes or databases they are indexed or 'abstracted in and showing if they are available electronical1y. A, print-out of such a database could serve as an annotated bibliography, a finding guide, and as a checklist of engineering education periodicals and conference proceedings. Such a print-out could then be published by ASEE in its Guide to the Literature series or as an additional conference paper. As a result, the engineering education literature of ASEE and other organizations or publishers could be more easily identified and utilized by those who create it and by those who would benefit the most from it, namely engineering educators

Engineering Education Periodicals and Proceedings: Increasing Awareness of and Access to the Literature

In the vast realm, of engineering literature there is a set of publications that is often unknown and certainly underutilized: engineering education periodicals and proceedings. These publications can easily be overlooked by engineering faculty, researchers, students, librarians or information professionals, and others who may not be fully aware of their existence or content. There has been a need for a definitive list of such publications for some time. This paper presents an initial list of these hems as the first step to make them more accessible to those in engineering education who may need them. The next step wil1 be to create a descriptive database of these items, briefly detailing their content, stating who publishes them, indicating what indexes or databases they are indexed or 'abstracted in and showing if they are available electronical1y. A, print-out of such a database could serve as an annotated bibliography, a finding guide, and as a checklist of engineering education periodicals and conference proceedings. Such a print-out could then be published by ASEE in its Guide to the Literature series or as an additional conference paper. As a result, the engineering education literature of ASEE and other organizations or publishers could be more easily identified and utilized by those who create it and by those who would benefit the most from it, namely engineering educators

Selective Guide to Literature on Aerospace Engineering

The term aerospace incorporates all aspects of flight including aviation, aeronautics, and astronautics. This ASEE Selective Guide to Literature on Aerospace Engineering identifies essential sources of information according to their function and format. The Guide will be useful for practicing engineers, engineering faculty, and engineering students and all who need to know where to look for information on a variety of topics in aerospace engineering. Librarians, library and information science students, and other information professionals will find it useful for planning access services and for collection development. From the launching of balloons in the 19th century to the airplane and spacecraft flights of this century, the aerospace literature has recorded scientific, governmental, industrial, and commercial efforts and achievements. The literature of aerospace engineering over the past 100 years remains of current interest, as knowledge in this field is cumulative and relevant to both historians and practitioners. The entire aerospace effort continues to command a high profile in modern society and is of benefit to people everywhere. As the field of aerospace engineering continues to grow and change, it will be even more important to track its activities and accomplishments through the literature sources listed here. This Guide includes bibliographies, guides to the literature, indexes and abstracts, Internet resources, encyclopedias, dictionaries, handbooks, directories, specifications and standards, government documents, statistical sources, selected periodicals, and selected conference proceedings. Selections are based on the compilers\u27 knowledge and experience in engineering librarianship and interlibrary loan services. Members of the ASEE Engineering Libraries Division and the SLA Aerospace and Engineering Divisions were generous with their input and suggestions. Publishers were occasionally inserted as assumed corporate authors. One such example is Jane\u27s Information Group. The resulting advantage is that all publications for a publisher were then grouped together

Clinical and biological significance of miR-23b and miR-193a in human hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is the most common cancer of the liver with a very poor prognosis. The dysregulation of microRNAs (miRs) is indeed implicated in HCC onset and progression. In this study, we have evaluated the expression of miR-23b and miR-193a in a large cohort of 59 and 67 HCC patients, respectively. miR-23b and miR-193a resulted significantly down-regulated in primary HCCs compared to their matched peritumoral counterparts. Furthermore, patients with higher miR-193a expression exhibited longer OS and DFS, suggesting that miR-193a may be a molecular prognostic factor for HCC patients. Since the regulation of miRs by DNA methylation may occur in human cancers, we verified whether the down-modulation of miR-23b and miR-193a in HCC tissues could be related to DNA methylation. An inverse trend between miR-23b expression and DNA methylation was observed, indicating that miR-23b can be epigenetically regulated. By contrast, the down-regulation of miR-193a was not mediated by DNA methylation. To verify the potential role of miR-23b and miR-193a as responsive molecular targets in vitro, we used the inhibitor of DNA methylation 5-aza-dC to restore miR-23b expression level in combination with miR-193a transfection. The combined treatment led to a significant inhibition of cellular proliferation and migration. Taken together, our findings provide evidence that miR-23b and miR-193a may be molecular diagnostic and prognostic factors for HCC; furthermore, miR-23b and miR-193a are responsive molecular targets for limiting HCC cell aggressiveness in combination with the epigenetic drug 5-aza-dC. Moreover, our results provide new advances in the epigenetic regulation of these miRs in HCC

The Theoretical Description for the Perylaldehyde Aldoxyme Anodic Electrochemical Determination, Assisted by the Novel Squaraine Dye Composite with Copper(ii) Sulfide Nanoparticles

In this work the perillaldehyde aldoxime electrochemical determination on an anode, modified by squaraine dye composite with copper sulfide nanoparticles is analyzed. The electroanalytical process involves the formation of trivalent copper species, capable to oxidize the analyte by two parallel mechanisms. The correspondent mathematical model, correspondent to both of them, has been developed and analyzed by means of linear stability theory and bifurcation analysis. The model analysis clearly shows that the composite of a squaraine dye in organic phase and bivalent copper sulfide in the inorganic phase may be an efficient electrode modifier for perillaldehyde aldoxime electrochemical determination on an anode. The electroanalytical process will be mostly kinetically-controlled with the possibility of the transfer to diffusion-controlled mode. On the other hand, both oscillatory and monotonic instabilities may be realized in the electroanalytical process, and their probability will depend on the direction of the electroanalytical scenario in the concrete conditions, due to the possibility of the formation of ionic compounds in the pre-surface layer. DOI: http://dx.doi.org/10.17807/orbital.v13i5.150

Analysis of a nanoparticle‑enriched fraction of plasma reveals miRNA candidates for down syndrome pathogenesis

Down syndrome (DS) is caused by the presence of part or all of a third copy of chromosome 21. DS is associated with several phenotypes, including intellectual disability, congenital heart disease, childhood leukemia and immune defects. Specific microRNAs (miRNAs/miR) have been described to be associated with DS, although none of them so far have been unequivocally linked to the pathology. The present study focuses to the best of our knowledge for the first time on the miRNAs contained in nanosized RNA carriers circulating in the blood. Fractions enriched in nanosized RNA-carriers were separated from the plasma of young participants with DS and their non-trisomic siblings and miRNAs were extracted. A microarray-based analysis on a small cohort of samples led to the identification of the three most abundant miRNAs, namely miR-16-5p, miR-99b-5p and miR-144-3p. These miRNAs were then profiled for 15 pairs of DS and non‑trisomic sibling couples by reverse transcription-quantitative polymerase chain reaction (RT-qPCR). Results identified a clear differential expression trend of these miRNAs in DS with respect to their non-trisomic siblings and gene ontology analysis pointed to their potential role in a number of typical DS features, including ‘nervous system development’, ‘neuronal cell body’ and certain forms of ‘leukemia’. Finally, these expression levels were associated with certain typical quantitative and qualitative clinical features of DS. These results contribute to the efforts in defining the DS‑associated pathogenic mechanisms and emphasize the importance of properly stratifying the miRNA fluid vehicles in order to probe biomolecules that are otherwise hidden and/or not accessible to (standard) analysis

THE THEORETICAL DESCRIPTION FOR ECOPIPAM ELECTROCHEMICAL DETERMINATION ON A COBALT(III) OXYHYDROXIDE-BASED MATERIAL

The theoretical description for ecopipam electrochemical determination, assisted by cobalt(III) oxyhydroxide has been given. The correspondent mathematical model has been developed and analyzed by means of linear stability theory and bifurcation analysis. It has been shown that, despite of the electrochemical instabilities, more probable to occur than for the similar systems, the cobalt (III) oxyhydroxide is an efficient electrode modifier for ecopipam determination. The electroanalytical process is diffusion-controlled