Halving the Casimir force with conductive oxides

The possibility to modify the strength of the Casimir effect by tailoring the dielectric functions of the interacting surfaces is regarded as a unique opportunity in the development of Micro- and NanoElectroMechanical Systems. In air, however, one expects that, unless noble metals are used, the electrostatic force arising from trapped charges overcomes the Casimir attraction, leaving no room for exploitation of Casimir force engineering at ambient conditions. Here we show that, in the presence of a conductive oxide, the Casimir force can be the dominant interaction even in air, and that the use of conductive oxides allows one to reduce the Casimir force up to a factor of 2 when compared to noble metals.Comment: modified version, accepted for publication in Phys Rev Let

Fiber-top atomic force microscope

We present the implementation of an atomic force microscope (AFM) based on fiber-top design. Our results demonstrate that the performances of fiber-top AFMs in contact mode are comparable to those of similar commercially available instruments. Our device thus represents an interesting\ud alternative to existing AFMs, particularly for applications outside specialized research laboratories, where a compact, user-friendly, and versatile tool might often be preferred

Interplay between antiferromagnetic order and spin polarization in ferromagnetic metal/electron-doped cuprate superconductor junctions

Recently we proposed a theory of point-contact spectroscopy and argued that the splitting of zero-bias conductance peak (ZBCP) in electron-doped cuprate superconductor point-contact spectroscopy is due to the coexistence of antiferromagnetic (AF) and d-wave superconducting orders [Phys. Rev. B {\bf 76}, 220504(R) (2007)]. Here we extend the theory to study the tunneling in the ferromagnetic metal/electron-doped cuprate superconductor (FM/EDSC) junctions. In addition to the AF order, the effects of spin polarization, Fermi-wave vector mismatch (FWM) between the FM and EDSC regions, and effective barrier are investigated. It is shown that there exits midgap surface state (MSS) contribution to the conductance to which Andreev reflections are largely modified due to the interplay between the exchange field of ferromagnetic metal and the AF order in EDSC. Low-energy anomalous conductance enhancement can occur which could further test the existence of AF order in EDSC. Finally, we propose a more accurate formula in determining the spin polarization value in combination with the point-contact conductance data.Comment: 9 pages, 8 figure

High-Q nested resonator in an actively stabilized optomechanical cavity

Experiments involving micro- and nanomechanical resonators need to be carefully designed to reduce mechanical environmental noise. A small scale on-chip approach is to add an additional resonator to the system as a mechanical low-pass filter. Unfortunately, the inherent low frequency of the low-pass filter causes the system to be easily excited mechanically. Fixating the additional resonator ensures that the resonator itself can not be excited by the environment. This, however, negates the purpose of the low-pass filter. We solve this apparent paradox by applying active feedback to the resonator, thereby minimizing the motion with respect the front mirror of an optomechanical cavity. Not only does this method actively stabilize the cavity length, but it also retains the on-chip vibration isolation.Comment: Minor adjustments mad

Журнал кримських караїмів “Бизым йол” (“Наш шлях”) у світлі традицій караїмської преси і національної політики Кримської АРСР

В статье содержится описание караимских периодических изданий начала ХХ века, их целей и задачи, объема, основных отделов, исследуется отражение в караимской периодике процессов национального культурного ренессанса, изучается связь этнических изданий караимов с общественно-политической жизнью караимской общины.Стаття містить опис караїмських видань початку ХХ століття, з'ясовує їхні цілі і завдан-ня, обсяг, основні розділи; досліджує відбиття у караїмській періодиці процесів національного культурного ренесансу; вивчає зв'язок етнічних видань караїмів із суспільно-політичним життям караїмської громади.The article researches the Karaite mass media of the beginning of the XX century: its matters and tasks, volume, main sections, the reflection of the cultural renaissance in it and its connection with life of the Karaite community

Synthesis and biological evaluation of immunoconjugates of adriamycin and a human IgM linked by poly[N5-(2-hydroxyethyl)-l-glutamine

The synthesis and purification of radiolabelled immunoconjugates, composed of a human IgM monoclonal antibody (IgM 16.88) directed against an intracellular tumour-associated antigen, the drug carrier poly[N5-(2-hydroxyethyl)--glutamine] (PHEG) and the cytostatic drug adriamycin (ADR) are described. The immunoconjugates were constructed to allow selective release of ADR in the putatively acidic environment of the tumour through a novel acid-labile maleamic acid linker. The conjugate of PHEG and the acid-labile ADR derivative effectively released ADR in cytotoxic amounts at a pH of 6.0 as judged from incubation in buffer and from inhibition of the growth of HT-29 colon tumour cells in vitro. Immunoconjugates were prepared by coupling of PHEG-ADR having a hydrolytically stable amide bond with 131I-labelled antibody through thioether bond formation involving a single thiol group at the C-terminus of the polymer chain and maleimido groups introduced onto th

Casimir-like effect on a granular pile

We investigate experimentally a Casimir-like effect in a three-dimensional pile of rice, which has a power-law avalanche size distribution. We observe the change in distance between two Plexiglas sheets placed on the pile parallel to each other and parallel to the mean avalanche flow direction, while rice grains are continuously and uniformly falling on top of the pile. The resulting avalanches are fluctuations, confinement of which is found to drive the two plates together. During 25-h experimental runs, for initial intersheet distances ranging from 20.0 to 90.0 mm we observe changes in the range from 6.0 mm to less than 1.0 mm. A similar distance dependence is obtained from a simple analytical model. © 2010 The American Physical Society

Factors associated with ethnical disparity in overall survival for patients with hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is an important cause of cancer-related death worldwide. Ethnical disparity in overall survival has been demonstrated for HCC patients in the United States (U.S.). We aimed to evaluate the contributors to this survival disparity. The SEER database was used to identify HCC patients from 2004 to 2012. Kaplan-Meier curves and Cox proportional hazard models were used to evaluate overall survival by ethnicity and the contributors to ethnical survival disparity. A total of 33 062 patients were included: 15 986 Non-Hispanic Whites, 6535 Hispanic Whites, 4842 African Americans, and 5699 Asians. Compared to Non-Hispanic Whites, African Americans had worse survival (HR, 1.18; 95%CI, 1.14-1.23), while Asians had a better survival (HR, 0.85; 95%CI, 0.82-0.89), and Hispanic Whites had a similar survival (HR, 1.01; 95%CI, 0.97-1.05). Multivariate Cox analysis identified that tumor presentation- and treatment-related factors significantly contributed to the ethnical survival disparity. Especially, tumor size was the most important contributor (HR, 1.11; 95%CI, 1.07-1.16). There is no ethnical survival disparity in patients undergoing liver transplantation and sub-analysis of patients within the Milan criteria for liver transplantation demonstrated no significant survival disparity between African Americans and non-Hispanic Whites in transplantation adjustment analysis (HR, 1.23; 95%CI, 1.11-1.35 in non-adjustment analysis to HR, 1.05; 95%CI, 0.95-1.15 after adjustment). Finally, no important contributor to the superior overall survival in Asians was identified. In conclusion, poor tumor presentation at diagnosis, limited benefit from resection and restricted utilization of liver transplantation are important contributors to poorer survival of African Americans with HCC

The Critical Behaviour of the Spin-3/2 Blume-Capel Model in Two Dimensions

The phase diagram of the spin-3/2 Blume-Capel model in two dimensions is explored by conventional finite-size scaling, conformal invariance and Monte Carlo simulations. The model in its $\tau$-continuum Hamiltonian version is also considered and compared with others spin-3/2 quantum chains. Our results indicate that differently from the standard spin-1 Blume-Capel model there is no multicritical point along the order-disorder transition line. This is in qualitative agreement with mean field prediction but in disagreement with previous approximate renormalization group calculations. We also presented new results for the spin-1 Blume-Capel model.Comment: latex 18 pages, 4 figure