Spin precession in the Schwarzschild spacetime: circular orbits

We study the behavior of nonzero rest mass spinning test particles moving along circular orbits in the Schwarzschild spacetime in the case in which the components of the spin tensor are allowed to vary along the orbit, generalizing some previous work.Comment: To appear on Classical and Quantum Gravity, 200

Obscuration and Origin of Nuclear X-ray emission in FR I Radio Galaxies

We present X-ray observations of the nuclear region of 25 Fanaroff-Riley I radio galaxies from the 3CRR and B2 catalogs, using data from the Chandra and XMM archives. We find the presence of a X-ray Central Compact Core (CCCX) in 13/25 sources, in 3/25 sources the detection of a CCCX is uncertain, while in the remaining 9/25 sources no CCCX is found. All the sources are embedded in a diffuse soft X-ray component, generally on kpc-scales, which is in agreement with the halo of the host galaxy and/or with the intracluster medium. The X-ray spectra of the cores are described by a power law with photon indices Gamma=1.1 - 2.6. In 8 sources excess absorption over the Galactic value is detected, with rest-frame column densities N_H^z ~ 10^20 - 10^21 cm^-2; thus, we confirm the previous claim based on optical data that most FRI radio galaxies lack a standard optically-thick torus. We find significant correlations between the X-ray core luminosity and the radio and optical luminosities, suggesting that at least a fraction of the X-ray emission originates in a jet; however, the origin of the X-rays remains ambiguous. If the X-ray emission is entirely attributed to an isotropic, accretion-related component, we find very small Eddington ratios, L_bol/L_Edd ~ 10^-3 - 10^-8, and we calculate the radiative efficiency to be eta ~ 10^-2 - 10^-6, based on the Bondi accretion rates from the spatial analysis. This suggests that radiatively inefficient accretion flows are present in the cores of low-power radio galaxies.Comment: 20 pages, 7 figures, accepted for publication in The Astrophysical Journa

Differential gene expression in sugarcane induced by salicylic acid and under water deficit conditions.

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Procedimentos para indução de calos embriogênicos em algodão.

bitstream/CNPA/18348/1/CIRTEC103.pd

Structural properties of crumpled cream layers

The cream layer is a complex heterogeneous material of biological origin which forms spontaneously at the air-milk interface. Here, it is studied the crumpling of a single cream layer packing under its own weight at room temperature in three-dimensional space. The structure obtained in these circumstances has low volume fraction and anomalous fractal dimensions. Direct means and noninvasive NMR imaging technique are used to investigate the internal and external structure of these systems.Comment: 9 pages, 4 figures, accepted in J. Phys. D: Appl. Phy

Telomerase reverse transcriptase locus polymorphisms and cancer risk: a field synopsis and meta-analysis.

BACKGROUND: Several recent studies have provided evidence that polymorphisms in the telomerase reverse transcriptase (TERT) gene sequence are associated with cancer development, but a comprehensive synopsis is not available. We conducted a systematic review and meta-analysis of the available molecular epidemiology data regarding the association between TERT locus polymorphisms and predisposition to cancer. METHODS: A systematic review of the English literature was conducted by searching PubMed, Embase, Cancerlit, Google Scholar, and ISI Web of Knowledge databases for studies on associations between TERT locus polymorphisms and cancer risk. Random-effects meta-analysis was performed to pool per-allele odds ratios for TERT locus polymorphisms and risk of cancer, and between-study heterogeneity and potential bias sources (eg, publication and chasing bias) were assessed. Because the TERT locus includes the cleft lip and palate transmembrane 1-like (CLPTM1L) gene, which is in linkage disequilibrium with TERT, CLPTM1L polymorphisms were also analyzed. Cumulative evidence for polymorphisms with statistically significant associations was graded as "strong," "moderate," and "weak" according to the Venice criteria. The joint population attributable risk was calculated for polymorphisms with strong evidence of association. RESULTS: Eighty-five studies enrolling 490 901 subjects and reporting on 494 allelic contrasts were retrieved. Data were available on 67 TERT locus polymorphisms and 24 tumor types, for a total of 221 unique combinations of polymorphisms and cancer types. Upon meta-analysis, a statistically significant association with the risk of any cancer type was found for 22 polymorphisms. Strong, moderate, and weak cumulative evidence for association with at least one tumor type was demonstrated for 11, 9, and 14 polymorphisms, respectively. For lung cancer, which was the most studied tumor type, the estimated joint population attributable risk for three polymorphisms (TERT rs2736100, intergenic rs4635969, and CLPTM1L rs402710) was 41%. Strong evidence for lack of association was identified for five polymorphisms in three tumor types. CONCLUSIONS: To our knowledge, this is the largest collection of data for associations between TERT locus polymorphisms and cancer risk. Our findings support the hypothesis that genetic variability in this genomic region can modulate cancer susceptibility in humans.This work was in part supported by a grant from the Italian Association for Research on Cancer (AIRC Veneto Regional fund 2008-2011 to SM and DN).This is the author accepted manuscript. The final version is available from Oxford University Press via http://dx.doi.org/10.1093/jnci/djs22

[I Submitted a Paper to Acta Médica Portugal. What Happens Now?]

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Spinocerebellar ataxia types 1, 2, 3, and 6: disease severity and nonataxia symptoms.

OBJECTIVE: To identify factors that determine disease severity and clinical phenotype of the most common spinocerebellar ataxias (SCAs), we studied 526 patients with SCA1, SCA2, SCA3. or SCA6. METHODS: To measure the severity of ataxia we used the Scale for the Assessment and Rating of Ataxia (SARA). In addition, nonataxia symptoms were assessed with the Inventory of Non-Ataxia Symptoms (INAS). The INAS count denotes the number of nonataxia symptoms in each patient. RESULTS: An analysis of covariance with SARA score as dependent variable and repeat lengths of the expanded and normal allele, age at onset, and disease duration as independent variables led to multivariate models that explained 60.4% of the SARA score variance in SCA1, 45.4% in SCA2, 46.8% in SCA3, and 33.7% in SCA6. In SCA1, SCA2, and SCA3, SARA was mainly determined by repeat length of the expanded allele, age at onset, and disease duration. The only factors determining the SARA score in SCA6 were age at onset and disease duration. The INAS count was 5.0 +/- 2.3 in SCA1, 4.6 +/- 2.2 in SCA2, 5.2 +/- 2.5 in SCA3, and 2.0 +/- 1.7 in SCA6. In SCA1, SCA2, and SCA3, SARA score and disease duration were the strongest predictors of the INAS count. In SCA6, only age at onset and disease duration had an effect on the INAS count. CONCLUSIONS: Our study suggests that spinocerebellar ataxia (SCA) 1, SCA2, and SCA3 share a number of common biologic properties, whereas SCA6 is distinct in that its phenotype is more determined by age than by disease-related factors

Thoughts about the Impact Factor

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