21,676 research outputs found

    Views from the Ohio manufacturing index

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    An introduction to the experimental Ohio Manufacturing Index and a brief examination of the recent patterns of manufacturing growth occurring in the state.Manufactures - Ohio ; Ohio ; Economic indicators - Ohio

    Calibration of a fission gas monitor

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    Calibration of argon gas neutron activation sampling devic

    Evaluating the role of citizen science in biological investigations

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    Considering recent and predicted ecological changes (caused by global climate change), baseline monitoring of biological diversity becomes an extremely useful record to have. Citizen science provides a unique, low-cost, high output method of attaining large data sets which has already been implemented in several studies. They are used by major bodies such as the Natural History Museum, OPAL and the RSPB. Despite this concerns lie with the accuracy of the data – can volunteers really produce real data? In this study various aspects were investigated, firstly the current public opinion about citizen science, how we can train volunteers carrying out surveys, and the kinds of method suitable for biological monitoring by citizen scientists. This report finds a generally good level of public literacy in terms of the existence and the potential of, citizen science. Participant confidence significantly increases once a volunteer has carried out a survey – but this does not show any relationship with accuracy. It is concluded that estimation of abundance must be embedded with training and validation methods, and it is recommended further work is carried out into robust online training and validation

    Flucytosine and cryptococcosis: time to urgently address the worldwide accessibility of a 50-year-old antifungal.

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    Current, widely accepted guidelines for the management of HIV-associated cryptococcal meningoencephalitis (CM) recommend amphotericin B combined with flucytosine (5-FC) for ≥2 weeks as the initial induction treatment of choice. However, access to flucytosine in Africa and Asia, where disease burden is greatest, is inadequate at present. While research into identifying effective and well-tolerated antifungal combinations that do not contain flucytosine continues, an ever-increasing body of evidence from in vitro, in vivo and clinical studies points to the benefits of flucytosine in the treatment of CM in both intravenous combinations with amphotericin B and oral combinations with high-dose fluconazole. This article provides an up-to-date review of this evidence, and the current issues and challenges regarding increasing access to this key component of combination antifungal therapy for cryptococcosis

    Pressure-driven flow of solid helium

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    The recent torsional oscillator results of Kim and Chan suggest a supersolid phase transition in solid 4He. We have used a piezoelectrically driven diaphragm to study the flow of solid helium through an array of capillaries. Our measurements showed no indication of low temperature flow, placing stringent restrictions on supersolid flow in response to a pressure difference. The average flow speed at low temperatures was less than 1.2x10-14 m/s, corresponding to a supersolid velocity at least 7 orders of magnitude smaller than the critical velocities inferred from the torsional oscillator measurements.Comment: 4 pages, 3 figure

    Drought-Induced Amplification of Saint Louis encephalitis virus, Florida

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    We used a dynamic hydrology model to simulate water table depth (WTD) and quantify the relationship between Saint Louis encephalitis virus (SLEV) transmission and hydrologic conditions in Indian River County, Florida, from 1986 through 1991, a period with an SLEV epidemic. Virus transmission followed periods of modeled drought (specifically low WTDs 12 to 17 weeks before virus transmission, followed by a rising of the water table 1 to 2 weeks before virus transmission). Further evidence from collections of Culex nigripalpus (the major mosquito vector of SLEV in Florida) suggests that during extended spring droughts vector mosquitoes and nestling, juvenile, and adult wild birds congregate in selected refuges, facilitating epizootic amplification of SLEV. When the drought ends and habitat availability increases, the SLEV-infected Cx. nigripalpus and wild birds disperse, initiating an SLEV transmission cycle. These findings demonstrate a mechanism by which drought facilitates the amplification of SLEV and its subsequent transmission to humans

    User benefits and funding strategies

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    The justification, economic and technological benefits of NASA Space Programs (aside from pure scientific objectives), in improving the quality of life in the United States is discussed and outlined. Specifically, a three-step, systematic method is described for selecting relevant and highly beneficial payloads and instruments for the Interim Upper Stage (IUS) that will be used with the space shuttle until the space tug becomes available. Viable Government and private industry cost-sharing strategies which would maximize the number of IUS payloads, and the benefits obtainable under a limited NASA budget were also determined. Charts are shown which list the payload instruments, and their relevance in contributing to such areas as earth resources management, agriculture, weather forecasting, and many others
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