Overview of the first HyMeX Special Observation Period over Italy: observations and model results

Abstract. The Special Observation Period (SOP1), part of the HyMeX campaign (Hydrological cycle in the Mediterranean Experiments, 5 September–6 November 2012), was dedicated to heavy precipitation events and flash floods in the western Mediterranean, and three Italian hydro-meteorological monitoring sites were identified: Liguria–Tuscany, northeastern Italy and central Italy. The extraordinary deployment of advanced instrumentation, including instrumented aircrafts, and the use of several different operational weather forecast models, including hydrological models and marine models, allowed an unprecedented monitoring and analysis of high-impact weather events around the Italian hydro-meteorological sites. This activity has seen strong collaboration between the Italian scientific and operational communities. In this paper an overview of the Italian organization during SOP1 is provided, and selected Intensive Observation Periods (IOPs) are described. A significant event for each Italian target area is chosen for this analysis: IOP2 (12–13 September 2012) in northeastern Italy, IOP13 (15–16 October 2012) in central Italy and IOP19 (3–5 November 2012) in Liguria and Tuscany. For each IOP the meteorological characteristics, together with special observations and weather forecasts, are analyzed with the aim of highlighting strengths and weaknesses of the forecast modeling systems, including the hydrological impacts. The usefulness of having different weather forecast operational chains characterized by different numerical weather prediction models and/or different model set up or initial conditions is finally shown for one of the events (IOP19)

Assessing the coastal hazard of Medicane Ianos through ensemble modelling

On 18 September 2020, Medicane Ianos hit the western coast of Greece, resulting in flooding and severe damage at several coastal locations. In this work, we aim at evaluating its impact on sea conditions and the associated uncertainty through the use of an ensemble of numerical simulations. We applied a coupled wave–current model to an unstructured mesh, representing the whole Mediterranean Sea, with a grid resolution increasing in the Ionian Sea along the cyclone path and the landfall area. To investigate the uncertainty in modelling sea levels and waves for such an intense event, we performed an ensemble of ocean simulations using several coarse (10 km) and high-resolution (2 km) meteorological forcings from different mesoscale models. The performance of the ocean and wave models was evaluated against observations retrieved from fixed monitoring stations and satellites. All model runs emphasized the occurrence of severe sea conditions along the cyclone path and at the coast. Due to the rugged and complex coastline, extreme sea levels are localized at specific coastal sites. However, numerical results show a large spread of the simulated sea conditions for both the sea level and waves, highlighting the large uncertainty in simulating this kind of extreme event. The multi-model and multi-physics approach allows us to assess how the uncertainty propagates from meteorological to ocean variables and the subsequent coastal impact. The ensemble mean and standard deviation were combined to prove the hazard scenarios of the potential impact of such an extreme event to be used in a flood risk management plan.</p

"Delirium Day": A nationwide point prevalence study of delirium in older hospitalized patients using an easy standardized diagnostic tool

Background: To date, delirium prevalence in adult acute hospital populations has been estimated generally from pooled findings of single-center studies and/or among specific patient populations. Furthermore, the number of participants in these studies has not exceeded a few hundred. To overcome these limitations, we have determined, in a multicenter study, the prevalence of delirium over a single day among a large population of patients admitted to acute and rehabilitation hospital wards in Italy. Methods: This is a point prevalence study (called "Delirium Day") including 1867 older patients (aged 65 years or more) across 108 acute and 12 rehabilitation wards in Italian hospitals. Delirium was assessed on the same day in all patients using the 4AT, a validated and briefly administered tool which does not require training. We also collected data regarding motoric subtypes of delirium, functional and nutritional status, dementia, comorbidity, medications, feeding tubes, peripheral venous and urinary catheters, and physical restraints. Results: The mean sample age was 82.0 \ub1 7.5 years (58 % female). Overall, 429 patients (22.9 %) had delirium. Hypoactive was the commonest subtype (132/344 patients, 38.5 %), followed by mixed, hyperactive, and nonmotoric delirium. The prevalence was highest in Neurology (28.5 %) and Geriatrics (24.7 %), lowest in Rehabilitation (14.0 %), and intermediate in Orthopedic (20.6 %) and Internal Medicine wards (21.4 %). In a multivariable logistic regression, age (odds ratio [OR] 1.03, 95 % confidence interval [CI] 1.01-1.05), Activities of Daily Living dependence (OR 1.19, 95 % CI 1.12-1.27), dementia (OR 3.25, 95 % CI 2.41-4.38), malnutrition (OR 2.01, 95 % CI 1.29-3.14), and use of antipsychotics (OR 2.03, 95 % CI 1.45-2.82), feeding tubes (OR 2.51, 95 % CI 1.11-5.66), peripheral venous catheters (OR 1.41, 95 % CI 1.06-1.87), urinary catheters (OR 1.73, 95 % CI 1.30-2.29), and physical restraints (OR 1.84, 95 % CI 1.40-2.40) were associated with delirium. Admission to Neurology wards was also associated with delirium (OR 2.00, 95 % CI 1.29-3.14), while admission to other settings was not. Conclusions: Delirium occurred in more than one out of five patients in acute and rehabilitation hospital wards. Prevalence was highest in Neurology and lowest in Rehabilitation divisions. The "Delirium Day" project might become a useful method to assess delirium across hospital settings and a benchmarking platform for future surveys

Measurement of antiproton production from antihyperon decays in pHe collisions at √sNN=110GeV

The interpretation of cosmic antiproton flux measurements from space-borne experiments is currently limited by the knowledge of the antiproton production cross-section in collisions between primary cosmic rays and the interstellar medium. Using collisions of protons with an energy of 6.5 TeV incident on helium nuclei at rest in the proximity of the interaction region of the LHCb experiment, the ratio of antiprotons originating from antihyperon decays to prompt production is measured for antiproton momenta between 12 and 110GeV\!/c . The dominant antihyperon contribution, namely Λ¯ → p¯ π+ decays from promptly produced Λ¯ particles, is also exclusively measured. The results complement the measurement of prompt antiproton production obtained from the same data sample. At the energy scale of this measurement, the antihyperon contributions to antiproton production are observed to be significantly larger than predictions of commonly used hadronic production models

Effects of GaAs pulsed laser on ATP concentration and ATPase activity in vitro and in vivo

Effects of GaAs pulsed laser on ATP concentration and ATPase activity in vitro and in vivo

Determination of ATP in Macrobiotus richtersi using luminometric techniques

Determination of ATP in Macrobiotus richtersi using luminometric technique

Determination of ATP and ATPase activity in Macrobiotus richtersi and in Pseudobiotus megalonix (Tardigrada)

Determination of ATP and ATPase activity in Macrobiotus richtersi and in Pseudobiotus megalonix (Tardigrada