Sensory geographies and defamiliarisation: migrant women encounter Brighton Beach

This article’s starting point is a sensory, reflexive walk taken on Brighton seafront and beach, by fourteen migrant women and some of their children. It goes on to open up a wider discussion about the cultural politics and affective resonances, for refugees and migrants, of beaches. By discussing their sensory experiences of the beach, we begin to understand their ‘ostranenie’, or defamiliarisation, of making the familiar strange. We also see how evocative such sense-making can be, as the women compare their past lives to this, perceiving their lifeworld through a filter of migrancy. The article goes onto discuss the broader cultural symbolism of beaches, which are a site of contestation over national values, boundaries, and belonging. As well as discussing sensory methodology in this article, and explaining the locale of Brighton Beach itself, it concludes with some wider thinking of the cultural politics of beach spaces and migrant perceptions

The contribution of X-linked coding variation to severe developmental disorders

Abstract: Over 130 X-linked genes have been robustly associated with developmental disorders, and X-linked causes have been hypothesised to underlie the higher developmental disorder rates in males. Here, we evaluate the burden of X-linked coding variation in 11,044 developmental disorder patients, and find a similar rate of X-linked causes in males and females (6.0% and 6.9%, respectively), indicating that such variants do not account for the 1.4-fold male bias. We develop an improved strategy to detect X-linked developmental disorders and identify 23 significant genes, all of which were previously known, consistent with our inference that the vast majority of the X-linked burden is in known developmental disorder-associated genes. Importantly, we estimate that, in male probands, only 13% of inherited rare missense variants in known developmental disorder-associated genes are likely to be pathogenic. Our results demonstrate that statistical analysis of large datasets can refine our understanding of modes of inheritance for individual X-linked disorders

The effect of phoneme identification and letter name knowledge on grade one reading achievement

Thesis (Ed.M.)--Boston UniversityPLEASE NOTE: Boston University Libraries did not receive an Authorization To Manage form for this thesis or dissertation. It is therefore not openly accessible, though it may be available by request. If you are the author or principal advisor of this work and would like to request open access for it, please contact us at [email protected]. Thank you.2031-01-0