69 research outputs found

    A comparative study of major element rock analyses by argon plasma emission and atomic absorption/emission spectrophotometry.

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    Dept. of Geology and Geological Engineering. Paper copy at Leddy Library: Theses & Major Papers - Basement, West Bldg. / Call Number: Thesis1978 .Q957. Source: Masters Abstracts International, Volume: 40-07, page: . Thesis (M.A.Sc.)--University of Windsor (Canada), 1978

    LMDA Newsletter, July 2021

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    Contents include: Conference Wrap-Up; Without Borders: Dramaturgy in the New Decade // Sin Fronteras: Dramaturgismo en laNueva Década; Save the Dates: 2022 LMDA International Conference Online & In-person in Philadelphia July 20-24, 2022: A Note from BQ; Reflections from a Virtual Bar; Region Facebook Groups.https://soundideas.pugetsound.edu/lmdanewsletter/1054/thumbnail.jp

    LMDA Canada: Canadian Newsletter, November 16, 1998

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    Contents include: Letter from the Editor, Effing the Ineffable, Adapting Theatre History, A Readiness to Receive, The Theatre Center Proudly Presents Body Geometry, Necessary Theatre Manifesto, Writing out Dramaturgy, Report from the Rock, Out of the Blocks and Onto the Track, Rocky Mountain Highs: Dramaturgy and the 1998 playRites Colony, News from the Factory Theatre, Theatre Centre Research Programhttps://soundideas.pugetsound.edu/lmdanewsletter/1030/thumbnail.jp

    LMDA Canada: Canadian Caucus Newsletter, November 1999

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    Contents include: LMDA Canadian Caucus Membership, Letter from the Editor, Survey Results, Canadian Dramaturtle Goes to Oz, Translation on the St. Lawrence, Experimenting with the Audience, Feeding My Habit or Why I Stopped Being a Dramaturg and Went Back to School, Mini-Conference on Dramaturgy 1999, Canadians in Chicago, War of the Worlds, Dramaturging Dr. Faustus, Inside the Process: A New Angle on the Spring Festival of New Plays, ScriptLab: Millennium Approacheshttps://soundideas.pugetsound.edu/lmdanewsletter/1029/thumbnail.jp

    LMDA Review, volume 9, issue 2

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    Contents include: Literary Managers and Dramaturgs of the Americas Annual Conference 1999 Setting the Table: A Working Retreat, The State of the Profession Round One, Call for Nominations LMDA President-Elect, On Elliot Hayes and the LMDA Prize, Early Career Dramaturg Program, Report on Canadian Caucus Meeting, Introducing Celise Kalke, Research at the Theater Center, Script Exchange, LMDA Online, Education in the Arts, A Team Approach to Dramaturgy at Cornish College of the Arts, Process Translation: Translator/Dramaturg Meets Actor/Translator, Jobs, Disruption in Job Line Service, Dramaturgy Focus Group Association for Theater in Higher Education Toronto Conference, Report on the Dramaturgy Focus Group ATHE 1999, Recent Publications by Members, and Literary Managers and Dramaturgs of the Americas Bibliography 1999https://soundideas.pugetsound.edu/lmdareview/1019/thumbnail.jp

    Review: The Newsletter of the Literary Managers and Dramaturgs of the Americas, volume 15, issue 1

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    Contents include: Dramaturgical Debris, LMDA Conference 2004 Life, Liberty, and the Pursuit of Happiness, The Production Notebooks Edited by Mark Bly: A Conversation between Danielle Mages Amato and D.J. Hopkins, Interviews with Past LMDA Presidents Alexis Greene and David Copelin, and LMDA Regional Updates Issue editors: D.J. Hopkins, Shelley Orr, Megan Monaghan, Madeleine Oldhamhttps://soundideas.pugetsound.edu/lmdareview/1030/thumbnail.jp

    LMDA Review, volume 11, issue 2

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    Contents include: A Letter to the Membership from the LMDA Board Chair, Dixon to the Guthrie, Office Update, Technology Notes, News from CEAD Montreal, LMDA Affiliates with ATHE, ATHE 2001 Practice, Theory, Technology and the New Student, Report on Canadian Caucus, Note to the Editor, The Experiment Tradition, Community and the Development of Scripts for Stage and Screen, A Collaborative Workshop, An Intern on Internships, Spotlight on Early Career Dramaturgs, Exciting News from the West Coast, Coming this Way, and Playscripts.com.https://soundideas.pugetsound.edu/lmdareview/1021/thumbnail.jp

    Expansion and Characterization of Human Melanoma Tumor-Infiltrating Lymphocytes (TILs)

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    Various immunotherapeutic strategies for cancer are aimed at augmenting the T cell response against tumor cells. Adoptive cell therapy (ACT), where T cells are manipulated ex vivo and subsequently re-infused in an autologous manner, has been performed using T cells from various sources. Some of the highest clinical response rates for metastatic melanoma have been reported in trials using tumor-infiltrating lymphocytes (TILs). These protocols still have room for improvement and furthermore are currently only performed at a limited number of institutions. The goal of this work was to develop TILs as a therapeutic product at our institution.TILs from 40 melanoma tissue specimens were expanded and characterized. Under optimized culture conditions, 72% of specimens yielded rapidly proliferating TILs as defined as at least one culture reaching ≥3×10(7) TILs within 4 weeks. Flow cytometric analyses showed that cultures were predominantly CD3+ T cells, with highly variable CD4+:CD8+ T cell ratios. In total, 148 independent bulk TIL cultures were assayed for tumor reactivity. Thirty-four percent (50/148) exhibited tumor reactivity based on IFN-γ production and/or cytotoxic activity. Thirteen percent (19/148) showed specific cytotoxic activity but not IFN-γ production and only 1% (2/148) showed specific IFN-γ production but not cytotoxic activity. Further expansion of TILs using a 14-day "rapid expansion protocol" (REP) is required to induce a 500- to 2000-fold expansion of TILs in order to generate sufficient numbers of cells for current ACT protocols. Thirty-eight consecutive test REPs were performed with an average 1865-fold expansion (+/- 1034-fold) after 14 days.TILs generally expanded efficiently and tumor reactivity could be detected in vitro. These preclinical data from melanoma TILs lay the groundwork for clinical trials of ACT

    The Science Performance of JWST as Characterized in Commissioning

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    This paper characterizes the actual science performance of the James Webb Space Telescope (JWST), as determined from the six month commissioning period. We summarize the performance of the spacecraft, telescope, science instruments, and ground system, with an emphasis on differences from pre-launch expectations. Commissioning has made clear that JWST is fully capable of achieving the discoveries for which it was built. Moreover, almost across the board, the science performance of JWST is better than expected; in most cases, JWST will go deeper faster than expected. The telescope and instrument suite have demonstrated the sensitivity, stability, image quality, and spectral range that are necessary to transform our understanding of the cosmos through observations spanning from near-earth asteroids to the most distant galaxies.Comment: 5th version as accepted to PASP; 31 pages, 18 figures; https://iopscience.iop.org/article/10.1088/1538-3873/acb29

    Lead Isotopes in Exploration for Basement-Hosted Structurally Controlled Unconformity-Related Uranium Deposits: Kiggavik Project (Nunavut, Canada)

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    Pb-isotopes have been proposed as pathfinders for sandstone-hosted unconformity-related U deposits, with isotope ratios providing information on mineralization timing and element remobilization and migration. Pb-isotopes proximal to mineralization display radiogenic signatures, often with ‘excess Pb’ suggestive of derivation from greater U concentrations than are currently present. The U deposits in the Kiggavik project area (west of Baker Lake, NU, Canada) are basement-hosted, contain several generations of pitchblende mineralization, display a strong structural control, and are located in fault-related fracture systems and foliation-parallel veinlets. Drill core samples were analysed by Inductively-Coupled Plasma-Mass Spectrometer (ICP-MS) for Pb isotopes following multi-acid total-digestion, reverse Aqua Regia partial-digestion, and weak-acid-leach attacks, to evaluate the utility of the respective dissolution methods in Pb-isotope pathfinder geochemistry. Partial-digestion results are similar to weak-acid-leach results, indicating that interpretation of Pb-isotope signatures can be carried out from partial-digestion data if weak-acid-leach data are unavailable. Application of this pathfinder method at Kiggavik shows that Pb-isotope ratios display systematic trends useful for exploration vectoring. Uranium-content-adjusted 206Pb/204Pb ratios and 206Pb/204Pb ‘excess-lead’ data highlight anomalous isotopic values. 207Pb/206Pb ratios display downhole trends complementary to location of mineralization. Three-dimensional (3D) distributions of Pb-isotope data at the Contact U prospect show systematic trends and form halos around the mineralization. Isotopic footprints are limited to <50 m from the mineralization outline, reflecting host-rock and structural control, but indicate areas with elevated potential for U mineralization and provide vectoring information within basement lithologies
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