Determining the feasibility of a method for improving bandwidth utilization of cable networks

While the cable television industry has made significant investments in infrastructure to improve the number and quality of services delivered to their end customers, they still face the problem of limited bandwidth of signals down the last mile of coaxial cable to the subscriber premises. This thesis investigates an approach devised by the author to overcome this limitation. The method involves clustering of channels in both the upstream and downstream directions in a DOCSIS compliant cable system. A model of this approach is made and the theoretical maximum throughput is calculated for several scenarios. Results are compared to performance of existing systems. It is found that proposed approach yields significantly more throughput for a given RF bandwidth than others in the comparison

What do loose groups tell us about galaxy formation?

We present the results of a Parkes Multibeam HI survey of six loose groups of galaxies analogous to the Local Group. This survey was sensitive to HI-rich objects in these groups to below 10^7 M(sun) of HI, and was designed to search for low mass, gas-rich satellite galaxies and potential analogs to the high-velocity clouds seen around the Milky Way. This survey detected a total of 79 HI-rich objects associated with the six groups, half of which were new detections. While the survey identified a small number of dwarf galaxies, no star-free HI clouds were discovered. The HI mass function of the six groups appears to be roughly flat as is that of the Local Group. The cumulative velocity distribution function (CVDF) of the HI-rich halos in the six groups is identical to that of the Local Group. Both of these facts imply that these groups are true analogs to the Local Group and that the Local Group is not unique in its lack of low-mass dwarf galaxies as compared to the predictions of cold dark matter models of galaxy formation. This survey also constrains the distance to and HI masses of the compact high-velocity clouds (CHVCs) around the Milky Way. The lack of CHVC analog detections implies that they are distributed within <160 kpc of the Milky Way and have average HI masses of <4x10^5 M(sun). The spatial distribution of CHVCs is consistent with the predictions of simulations for dark matter halos. Furthermore the CVDF of Local Group galaxies plus CHVCs matches the predicted CVDF of cold dark matter simulations of galaxy formation. This provides circumstantial evidence that CHVCs may be associated with low-mass dark matter halos.Comment: 4 pages, to appear in the proceedings of "Baryons in Dark Matter Halos" Eds R-J., Dettmar, U. Klein, P. Salucci, PoS, SISSA, http://pos.sissa.i

An HI census of Loose Groups of Galaxies

We present results from our Parkes Multibeam HI survey of 3 loose groups of galaxies that are analogous to the Local Group. This is a survey of groups containing only spiral galaxies with mean separations of a few hundred kpc, and total areas of approximately 1 sq. Mpc; groups similar to our own Local Group. We present a census of the HI-rich objects in these groups down to an M(HI), 1-sigma sensitivity ~7x10^5 M(sun), as well as the detailed properties of these detections from follow-up Compact Array observations. We found 7 new HI-rich members in the 3 groups, all of which have stellar counterparts and are, therefore, typical dwarf galaxies. The ratio of low-mass to high-mass gas-rich galaxies in these groups is less than in the Local Group meaning that the ``missing satellite'' problem is not unique. No high-velocity cloud analogs were found in any of the groups. If HVCs in these groups are the same as in the Local Group, this implies that HVCs must be located within ~300-400 kpc of the Milky Way.Comment: 6 pages, to appear in the ASP proceedings of IAU Symposium 217, "Recycling intergalactic and interstellar matter", eds. Pierre-Alain Duc, Jonathan Braine, Elias Brink

A genetic interaction between RAP1 and telomerase reveals an unanticipated role for RAP1 in telomere maintenance

RAP1 is one of the components of shelterin, the capping complex at chromosome ends or telomeres, although its role in telomere length maintenance and protection has remained elusive. RAP1 also binds subtelomeric repeats and along chromosome arms, where it regulates gene expression and has been shown to function in metabolism control. Telomerase is the enzyme that elongates telomeres, and its deficiency causes a premature aging in humans and mice. We describe an unanticipated genetic interaction between RAP1 and telomerase. While RAP1 deficiency alone does not impact on mouse survival, mice lacking both RAP1 and telomerase show a progressively decreased survival with increasing mouse generations compared to telomerase single mutants. Telomere shortening is more pronounced in Rap1-/- Terc-/- doubly deficient mice than in the single-mutant Terc-/- counterparts, leading to an earlier onset of telomere-induced DNA damage and degenerative pathologies. Telomerase deficiency abolishes obesity and liver steatohepatitis provoked by RAP1 deficiency. Using genomewide ChIP sequencing, we find that progressive telomere shortening owing to telomerase deficiency leads to re-localization of RAP1 from telomeres and subtelomeric regions to extratelomeric sites in a genomewide manner. These findings suggest that although in the presence of sufficient telomere reserve RAP1 is not a key factor for telomere maintenance and protection, it plays a crucial role in the context of telomerase deficiency, thus in agreement with its evolutionary conservation as a telomere component from yeast to humans.Research in the Blasco laboratory is funded by Spanish Ministry of Economy and Competitiveness (MINECO and FEDER) Project RETOS (SAF2013-45111-R), the European Research Council (ERC) Project TEL STEM CELL (ERC-2008-AdG/232854), and Fundacion Botin.S

The contribution of cohesin-SA1 to gene expression and chromatin architecture in two murine tissues

Cohesin, which in somatic vertebrate cells consists of SMC1, SMC3, RAD21 and either SA1 or SA2, mediates higher-order chromatin organization. To determine how cohesin contributes to the establishment of tissue-specific transcriptional programs, we compared genome-wide cohesin distribution, gene expression and chromatin architecture in cerebral cortex and pancreas from adult mice. More than one third of cohesin binding sites differ between the two tissues and these show reduced overlap with CCCTC-binding factor (CTCF) and are enriched at the regulatory regions of tissue-specific genes. Cohesin/CTCF sites at active enhancers and promoters contain, at least, cohesin-SA1. Analyses of chromatin contacts at the Protocadherin (Pcdh) and Regenerating islet-derived (Reg) gene clusters, mostly expressed in brain and pancreas, respectively, revealed remarkable differences that correlate with the presence of cohesin. We could not detect significant changes in the chromatin contacts at the Pcdh locus when comparing brains from wild-type and SA1 null embryos. In contrast, reduced dosage of SA1 altered the architecture of the Reg locus and decreased the expression of Reg genes in the pancreas of SA1 heterozygous mice. Given the role of Reg proteins in inflammation, such reduction may contribute to the increased incidence of pancreatic cancer observed in these animals.The Spanish Ministry of Economy and Competitiveness (MINECO) [BFU2013-48481-R to A.L.]; 'Ramon y Cajal' Contract [RYC-2010-06122 to A.C.]; Fundacion La Caixa [PhD Fellowship to S.R.]. Funding for open access charge: The Spanish Ministry of Economy and Competitiveness (MINECO) [BFU2013-48481-R]S

The Simons Observatory: Science goals and forecasts

The Simons Observatory (SO) is a new cosmic microwave background experiment being built on Cerro Toco in Chile, due to begin observations in the early 2020s. We describe the scientific goals of the experiment, motivate the design, and forecast its performance. SO will measure the temperature and polarization anisotropy of the cosmic microwave background in six frequency bands centered at: 27, 39, 93, 145, 225 and 280 GHz. The initial configuration of SO will have three small-aperture 0.5-m telescopes and one large-aperture 6-m telescope, with a total of 60,000 cryogenic bolometers. Our key science goals are to characterize the primordial perturbations, measure the number of relativistic species and the mass of neutrinos, test for deviations from a cosmological constant, improve our understanding of galaxy evolution, and constrain the duration of reionization. The small aperture telescopes will target the largest angular scales observable from Chile, mapping ≈ 10% of the sky to a white noise level of 2 μK-arcmin in combined 93 and 145 GHz bands, to measure the primordial tensor-to-scalar ratio, r, at a target level of σ(r)=0.003. The large aperture telescope will map ≈ 40% of the sky at arcminute angular resolution to an expected white noise level of 6 μK-arcmin in combined 93 and 145 GHz bands, overlapping with the majority of the Large Synoptic Survey Telescope sky region and partially with the Dark Energy Spectroscopic Instrument. With up to an order of magnitude lower polarization noise than maps from the Planck satellite, the high-resolution sky maps will constrain cosmological parameters derived from the damping tail, gravitational lensing of the microwave background, the primordial bispectrum, and the thermal and kinematic Sunyaev-Zel'dovich effects, and will aid in delensing the large-angle polarization signal to measure the tensor-to-scalar ratio. The survey will also provide a legacy catalog of 16,000 galaxy clusters and more than 20,000 extragalactic sources

The Weak Mixing Angle from an SU(3) Symmetry at a TeV

The measured values of two electroweak gauge couplings appear to obey an approximate 5% SU(3) relation. Unless this is an accident caused by fortuitous Planck-scale physics, it suggests the presence of an SU(3) symmetry near the electroweak scale. We propose this to be a local SU(3) which spontaneously ``mixes'' with SU(2) x U(1) near a TeV. Although all the particles of the standard model are SU(3)-singlets, this symmetry relates the electroweak gauge couplings and can successfully predict the weak mixing angle with a precision of a few percent. Since this mechanism operates at a TeV, it does not require an energy desert and consequently can be embedded in theories of TeV-gravity

An H I Survey of Six Local Group Analogs. II. H I Properties of Group Galaxies

We have conducted an H I 21cm emission-line survey of six loose groups of galaxies chosen to be analogs to the Local Group. The survey was conducted using the Parkes multibeam instrument and the Australia Telescope Compact Array (ATCA) over a 1Mpc2 area and covering the full depth of each group, with an MH I sensitivity of 7 × 105 M. Our survey detected 110sources, 61 of which are associated with the six groups. All of these sources were confirmed with ATCA observations or were previously cataloged by HIPASS. The sources all have optical counterparts and properties consistent with dwarf irregular or late-type spiral galaxies. We present here the H I properties of the groups and their galaxies. We derive an H I mass function (HIMF) for the groups that is consistent with being flatter than the equivalent field HIMF. We also derive a circular velocity distribution function, tracing the luminous dark matter halos in the groups, that is consistent with those of the Local Group and HIPASS galaxies, both of which are shallower than that of clusters or predictions from cold dark matter models of galaxy formation

A Translational Polarization Rotator

We explore a free-space polarization modulator in which a variable phase introduction between right- and left-handed circular polarization components is used to rotate the linear polarization of the outgoing beam relative to that of the incoming beam. In this device, the polarization states are separated by a circular polarizer that consists of a quarter-wave plate in combination with a wire grid. A movable mirror is positioned behind and parallel to the circular polarizer. As the polarizer-mirror distance is separated, an incident liear polarization will be rotated through an angle that is proportional to the introduced phase delay. We demonstrate a prototype device that modulates Stokes Q and U over a 20% bandwidth

Mexico-UK Sub-millimeter Camera for AsTronomy

MUSCAT is a large format mm-wave camera scheduled for installation on the Large Millimeter Telescope Alfonso Serrano (LMT) in 2018. The MUSCAT focal plane is based on an array of horn coupled lumped-element kinetic inductance detectors optimised for coupling to the 1.1mm atmospheric window. The detectors are fed with fully baffled reflective optics to minimize stray-light contamination. This combination will enable background-limited performance at 1.1 mm across the full 4 arcminute field-of-view of the LMT. The easily accessible focal plane will be cooled to 100 mK with a new closed cycle miniature dilution refrigerator that permits fully continuous operation. The MUSCAT instrument will demonstrate the science capabilities of the LMT through two relatively short science programmes to provide high resolution follow-up surveys of Galactic and extra-galactic sources previously observed with the Herschel space observatory, after the initial observing campaigns. In this paper, we will provide an overview of the overall instrument design as well as an update on progress and scheduled installation on the LMT.Comment: Accepted for publication in the Journal of Low Temperature Detector