Informing Lottery Budget Decisions: HOPE and Pre-K

This report address how different allocations of lottery revenue between the Pre-K and HOPE programs might affect the achievement of the objectives of these two programs

Estimating Differential Responses to Local Fiscal Conditions: A Mixture Model Analysis

Alternative hypotheses exist regarding the impact of local sales and income taxes on local governments' taxing and spending decisions. One hypothesis is that local governments use sales and income taxes to pay for spending increases and leave property tax collections unchanged, while an equally plausible alternative is that local governments use sales and income taxes to reduce property taxes. Traditional models that restrict the impact of these local taxes to be the same across all local governments are not able to capture both types of behavior. The methodological difficulty lies in allowing for differences in behavior with no a priori information on which cities belong in which category. In this article, the authors use panel data to estimate a mixture model of spending and property tax response to the existence of local taxes. These empirical results provide evidence to support both hypotheses. These differences are both substantive and statistically significant

Topology Optimization of an Aircraft Wing

A Topology Optimization (TO) was conducted on an aircraft wing in order to mathematically determine an ideal structural case for future aircraft. TO generally involves iteratively reducing individual elemental density until the desired mass or volume constraint is met. Two different TO styles where approached: a global three-dimensional concept and a more traditional two-dimensional rib and spar optimization which more closely mimics the baseline model. All optimizations were compared against a baseline wing for von-Mises stress, displacement, and buckling. The objective of this research was to develop a design procedure maintaining the baseline structural integrity of the wing while reducing weight. As with many TO designs, Additive Manufacturing (AM) was studied as a means to produce the wing concerning both the feasibility of manufacture and as a logistical advantage compared to traditional means. Additionally, a fuel tank was integrated into the wing structure as a proof-of-concept for the potential benefits of AM. Finally, a 3D lattice structure was utilized as a conceptual method for improving current design methodology

DEVELOPING REGIONAL INPUT-OUTPUT MODELS FROM THE U.N. FORMAT ADOPTED BY THE U.S. IN THE NEW 1972 INPUT-OUTPUT MODEL

International Relations/Trade,

Using Rural Household Income Survey Data to Inform Poverty Analysis: An Example from Mozambique

This paper demonstrates that income survey data can be very informative in explaining the variation across households in the incidence and severity of absolute poverty using a rural household income data set for Mozambique. Results from regression analysis of the sources of variation are used to simulate the impact of alternative agricultural interventions or strategies on rural poverty. Complementarities in the insights gained from consumption expenditure and income surveys may justify the collection and analysis of both types of information, especially in Sub-Saharan Africa, the one region of the world where the incidence of poverty is increasing.Poverty analysis, household income surveys, agricultural development, Millenium Development Goals, Mozambique, Consumer/Household Economics, Food Security and Poverty, C21, I3, O13, O2, Q18,

Altering HIF-1α through 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure affects coronary vessel development.

Differential tissue hypoxia drives normal cardiogenic events including coronary vessel development. This requirement renders cardiogenic processes potentially susceptible to teratogens that activate a transcriptional pathway that intersects with the hypoxia-inducible factor (HIF-1) pathway. The potent toxin 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is known to cause cardiovascular defects by way of reduced myocardial hypoxia, inhibition of angiogenic stimuli, and alterations in responsiveness of endothelial cells to those stimuli. Our working hypothesis is that HIF-1 levels and thus HIF-1 signaling in the developing myocardium will be reduced by TCDD treatment in vivo during a critical stage and in particularly sensitive sites during heart morphogenesis. This inadequate HIF-1 signaling will subsequently result in outflow tract (OFT) and coronary vasculature defects. Our current data using the chicken embryo model showed a marked decrease in the intensity of immunostaining for HIF-1α nuclear expression in the OFT myocardium of TCDD-treated embryos. This area at the base of the OFT is particularly hypoxic during normal development; where endothelial cells initially form a concentrated anastomosing network known as the peritruncal ring; and where the left and right coronary arteries eventually connect to the aortic lumen. Consistent with this finding, anomalies of the proximal coronaries were detected after TCDD treatment and HIF-1α protein levels decreased in a TCDD dose-dependent manner