78 research outputs found

    Surface rupture of the Hundalee fault during the 2016 Mw 7.8 Kaikōura earthquake

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    The Hundalee fault is one of at least 20 faults that ruptured during the 2016 M w Mw 7.8 Kaikōura earthquake in the northeast of the South Island of New Zealand. Here, we document a 12‐km onshore section of the Hundalee fault that exhibited surface rupture from this event. To the northeast of our observations, the fault crosses the coast, and independent seabed surveys show that the 2016 rupture continued at least 2 km offshore. No surface rupture was observed across the southwestern section of the Hundalee fault, which crosses hilly vegetated terrain and poorly consolidated valley‐floor sediment. However, previous Interferometric Synthetic Aperture Radar (InSAR) analyses suggest that a 9‐km‐long section of the fault did rupture. Hence, the minimum length of the 2016 rupture along the Hundalee fault is 23 km. Field measurements indicate oblique dextral‐reverse slip along northeast‐trending Hundalee fault sections and reverse‐sinistral slip along north to north‐northeast‐trending sections. This is consistent with the regional principal horizontal shortening direction. Maximum vertical and horizontal offset measurements are 2.5±0.5 2.5±0.5 and 3.7±0.5  m 3.7±0.5  m , respectively. The discontinuous and irregular surface ruptures we observed are characteristic of a structurally immature fault, yet previous geological mapping indicates that the Hundalee fault is a regionally significant fault with >1‐km >1‐km late Cenozoic throw. Furthermore, a 60‐m‐wide sequence of fault rocks exposed by the rupture indicates that slip has localized into <10‐cm‐thick <10‐cm‐thick gouge zones, as anticipated for a mature fault. Therefore, a discrepancy exists between geological evidence of the Hundalee fault being a structurally mature fault and the characteristics of the 2016 rupture. We speculate that this signifies that the 2016 rupture was imposed on the Hundalee fault by movement across an inefficient multifault network rather than independent rupture of the Hundalee fault itself

    Extracting regulator activity profiles by integration of de novo motifs and expression data: characterizing key regulators of nutrient depletion responses in Streptomyces coelicolor

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    Determining transcriptional regulator activities is a major focus of systems biology, providing key insight into regulatory mechanisms and co-regulators. For organisms such as Escherichia coli, transcriptional regulator binding site data can be integrated with expression data to infer transcriptional regulator activities. However, for most organisms there is only sparse data on their transcriptional regulators, while their associated binding motifs are largely unknown. Here, we address the challenge of inferring activities of unknown regulators by generating de novo (binding) motifs and integrating with expression data. We identify a number of key regulators active in the metabolic switch, including PhoP with its associated directed repeat PHO box, candidate motifs for two SARPs, a CRP family regulator, an iron response regulator and that for LexA. Experimental validation for some of our predictions was obtained using gel-shift assays. Our analysis is applicable to any organism for which there is a reasonable amount of complementary expression data and for which motifs (either over represented or evolutionary conserved) can be identified in the genome

    Analysis of temporal transcription expression profiles reveal links between protein function and developmental stages of Drosophila melanogaster

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    Accurate gene or protein function prediction is a key challenge in the post-genome era. Most current methods perform well on molecular function prediction, but struggle to provide useful annotations relating to biological process functions due to the limited power of sequence-based features in that functional domain. In this work, we systematically evaluate the predictive power of temporal transcription expression profiles for protein function prediction in Drosophila melanogaster. Our results show significantly better performance on predicting protein function when transcription expression profile-based features are integrated with sequence-derived features, compared with the sequence-derived features alone. We also observe that the combination of expression-based and sequence-based features leads to further improvement of accuracy on predicting all three domains of gene function. Based on the optimal feature combinations, we then propose a novel multi-classifier-based function prediction method for Drosophila melanogaster proteins, FFPred-fly+. Interpreting our machine learning models also allows us to identify some of the underlying links between biological processes and developmental stages of Drosophila melanogaster

    Surface rupture of multiple crustal faults in the 2016 Mw 7.8 Kaikōura, New Zealand, earthquake

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    Multiple (>20 >20 ) crustal faults ruptured to the ground surface and seafloor in the 14 November 2016 M w Mw 7.8 Kaikōura earthquake, and many have been documented in detail, providing an opportunity to understand the factors controlling multifault ruptures, including the role of the subduction interface. We present a summary of the surface ruptures, as well as previous knowledge including paleoseismic data, and use these data and a 3D geological model to calculate cumulative geological moment magnitudes (M G w MwG ) and seismic moments for comparison with those from geophysical datasets. The earthquake ruptured faults with a wide range of orientations, sense of movement, slip rates, and recurrence intervals, and crossed a tectonic domain boundary, the Hope fault. The maximum net surface displacement was ∼12  m ∼12  m on the Kekerengu and the Papatea faults, and average displacements for the major faults were 0.7–1.5 m south of the Hope fault, and 5.5–6.4 m to the north. M G w MwG using two different methods are M G w MwG 7.7 +0.3 −0.2 7.7−0.2+0.3 and the seismic moment is 33%–67% of geophysical datasets. However, these are minimum values and a best estimate M G w MwG incorporating probable larger slip at depth, a 20 km seismogenic depth, and likely listric geometry is M G w MwG 7.8±0.2 7.8±0.2 , suggests ≤32% ≤32% of the moment may be attributed to slip on the subduction interface and/or a midcrustal detachment. Likely factors contributing to multifault rupture in the Kaikōura earthquake include (1) the presence of the subduction interface, (2) physical linkages between faults, (3) rupture of geologically immature faults in the south, and (4) inherited geological structure. The estimated recurrence interval for the Kaikōura earthquake is ≥5,000–10,000  yrs ≥5,000–10,000  yrs , and so it is a relatively rare event. Nevertheless, these findings support the need for continued advances in seismic hazard modeling to ensure that they incorporate multifault ruptures that cross tectonic domain boundaries

    Imports and isotopes: a modern baseline study for interpreting Iron Age and Roman trade in fallow deer antlers

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    The European Fallow deer (Dama dama dama) became extinct in the British Isles and most of continental Europe at the time of the Last Glacial Maximum, with the species becoming restricted to an Anatolian refugium (Masseti et al. 2008). Human-mediated reintroductions resulted in fallow populations in Rhodes, Sicily, Mallorca, Iberia and other parts of western Europe (Sykes et al. 2013). Eventually, the species was brought to Britain by the Romans during the 1st century AD, with a breeding population being established at Fishbourne Roman Palace (Sykes et al. 2011). The human influence on the present-day distribution of the species makes it particularly interesting from a zooarchaeological perspective. This paper describes my MSc research, as part of the AHRC-funded project Dama International: Fallow Deer and European Society 6000 BC–AD 1600, looking at antlers from Iron Age and Roman sites in Britain for evidence of trade in body parts and whether this can be elucidated by a parallel stable isotope study of modern fallow antlers of known provenance
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