2,284 research outputs found
Foreshock properties illuminate nucleation processes of slow and fast laboratory earthquakes
Laboratory experiments demonstrate that prior to fast laboratory earthquakes the fault begins to unlock and creep, causing foreshocks to coalesce in both space and time. This demonstrates that the evolution of foreshocks is closely connected to the fault slip velocity.Understanding the connection between seismic activity and the earthquake nucleation process is a fundamental goal in earthquake seismology with important implications for earthquake early warning systems and forecasting. We use high-resolution acoustic emission (AE) waveform measurements from laboratory stick-slip experiments that span a spectrum of slow to fast slip rates to probe spatiotemporal properties of laboratory foreshocks and nucleation processes. We measure waveform similarity and pairwise differential travel-times (DTT) between AEs throughout the seismic cycle. AEs broadcasted prior to slow labquakes have small DTT and high waveform similarity relative to fast labquakes. We show that during slow stick-slip, the fault never fully locks, and waveform similarity and pairwise differential travel times do not evolve throughout the seismic cycle. In contrast, fast laboratory earthquakes are preceded by a rapid increase in waveform similarity late in the seismic cycle and a reduction in differential travel times, indicating that AEs begin to coalesce as the fault slip velocity increases leading up to failure. These observations point to key differences in the nucleation process of slow and fast labquakes and suggest that the spatiotemporal evolution of laboratory foreshocks is linked to fault slip velocity
Contrasting alterations to synaptic and intrinsic properties in upper-cervical superficial dorsal horn neurons following acute neck muscle inflammation
Background:
Acute and chronic pain in axial structures, like the back and neck, are difficult to treat, and have incidence as high as 15%. Surprisingly, most preclinical work on pain mechanisms focuses on cutaneous structures in the limbs and animal models of axial pain are not widely available. Accordingly, we developed a mouse model of acute cervical muscle inflammation and assessed the functional properties of superficial dorsal horn (SDH) neurons.<p></p>
Results:
Male C57/Bl6 mice (P24-P40) were deeply anaesthetised (urethane 2.2?g/kg i.p) and the rectus capitis major muscle (RCM) injected with 40??l of 2% carrageenan. Sham animals received vehicle injection and controls remained anaesthetised for 2?hrs. Mice in each group were sacrificed at 2?hrs for analysis. c-Fos staining was used to determine the location of activated neurons. c-Fos labelling in carrageenan-injected mice was concentrated within ipsilateral (87% and 63% of labelled neurons in C1 and C2 segments, respectively) and contralateral laminae I - II with some expression in lateral lamina V. c-Fos expression remained below detectable levels in control and sham animals. In additional experiments, whole cell recordings were obtained from visualised SDH neurons in transverse slices in the ipsilateral C1 and C2 spinal segments. Resting membrane potential and input resistance were not altered. Mean spontaneous EPSC amplitude was reduced by ~20% in neurons from carrageenan-injected mice versus control and sham animals (20.63???1.05 vs. 24.64???0.91 and 25.87???1.32 pA, respectively). The amplitude (238???33 vs. 494???96 and 593???167 pA) and inactivation time constant (12.9???1.5 vs. 22.1???3.6 and 15.3???1.4?ms) of the rapid A type potassium current (IAr), the dominant subthreshold current in SDH neurons, were reduced in carrageenan-injected mice.<p></p>
Conclusions:
Excitatory synaptic drive onto, and important intrinsic properties (i.e., IAr) within SDH neurons are reduced two hours after acute muscle inflammation. We propose this time point represents an important transition period between peripheral and central sensitisation with reduced excitatory drive providing an initial neuroprotective mechanism during the early stages of the progression towards central sensitisation
Competition between preslip and deviatoric stress modulates precursors for laboratory earthquakes
Abstract Variations in elastic wave velocity and amplitude prior to failure have been documented in laboratory experiments as well as in a limited number of crustal earthquakes. These variations have generally been attributed to fault zone healing, changes in crack density, or pore fluid effects modulated dilatation or fault slip. However, the relationships between amplitude and velocity variations during the seismic cycle, and the underlying mechanisms of precursors to failure remain poorly understood. Here, we perform frictional shear experiments and measure the evolution of elastic wave velocity and amplitude throughout the laboratory seismic cycle. We find that elastic amplitudes and velocities undergo clear preseismic variations prior to fault failure. While preseismic amplitude reduction occurs early in the interseismic period, wave speed reduces later, just prior to failure. We perform a complementary set of stress oscillation experiments to quantify the response of seismic amplitudes and velocities to variations in the stress tensor. Taken together, our results indicate that preseismic amplitude variations are primarily controlled by fault slip rate and acceleration. On the other hand, elastic velocity responds to a combination of fault preslip which reduces seismic wavespeed and increasing stress in the wallrock, which increases wavespeed. Our data show that precursory changes in seismic wave speed may be more common than previously thought because they are masked by changes in wallrock stress. These results underscore the importance of continuous and long-term time-lapse monitoring of crustal faults for seismic hazard assessment and potential precursors to failure
The SWELLS survey. IV. Precision measurements of the stellar and dark matter distributions in a spiral lens galaxy
We construct a fully self-consistent mass model for the lens galaxy J2141 at
z=0.14, and use it to improve on previous studies by modelling its
gravitational lensing effect, gas rotation curve and stellar kinematics
simultaneously. We adopt a very flexible axisymmetric mass model constituted by
a generalized NFW dark matter halo and a stellar mass distribution obtained by
deprojecting the MGE fit to the high-resolution K'-band LGSAO imaging data of
the galaxy, with the (spatially constant) M/L ratio as a free parameter. We
model the stellar kinematics by solving the anisotropic Jeans equations. We
find that the inner logarithmic slope of the dark halo is weakly constrained
(gamma = 0.82^{+0.65}_{-0.54}), and consistent with an unmodified NFW profile.
We infer the galaxy to have (i) a dark matter fraction within 2.2 disk radii of
0.28^{+0.15}_{-0.10}, independent of the galaxy stellar population, implying a
maximal disk for J2141; (ii) an apparently uncontracted dark matter halo, with
concentration c_{-2} = 7.7_{-2.5}^{+4.2} and virial velocity v_{vir} =
242_{-39}^{+44} km/s, consistent with LCDM predictions; (iii) a slightly oblate
halo (q_h = 0.75^{+0.27}_{-0.16}), consistent with predictions from
baryon-affected models. Comparing the stellar mass inferred from the combined
analysis (log_{10} Mstar/Msun = 11.12_{-0.09}^{+0.05}) with that inferred from
SPS modelling of the galaxies colours, and accounting for a cold gas fraction
of 20+/-10%, we determine a preference for a Chabrier IMF over Salpeter IMF by
a Bayes factor of 5.7 (substantial evidence). We infer a value beta_{z} = 1 -
sigma^2_{z}/sigma^2_{R} = 0.43_{-0.11}^{+0.08} for the orbital anisotropy
parameter in the meridional plane, in agreement with most studies of local disk
galaxies, and ruling out at 99% CL that the dynamics of this system can be
described by a two-integral distribution function. [Abridged]Comment: Accepted for publication in MNRAS. 17 pages, 9 figure
The Mini AGN at the Center of the Elliptical Galaxy NGC 4552 with HST
The complex phenomenology shown by the UV-bright, variable spike first
detected with the Hubble Space Telescope (HST) at the center of the otherwise
normal galaxy NGC 4552 is further investigated with both HST imaging (FOC) and
spectroscopy (FOS). HST/FOC images taken in 1991, 1993, and 1996 in the near UV
have been analyzed in a homogeneous fashion, showing that the central spike has
brightened by a factor ~4.5 between 1991 and 1993, and has decreased its
luminosity by a factor ~2.0 between 1993 and 1996. FOS spectroscopy extending
from the near UV to the red side of the optical spectrum reveals a strong UV
continuum over the spectrum of the underlying galaxy, along with several
emission lines in both the UV and the optical ranges. In spite of the low
luminosity of the UV continuum of the spike (~3*10^5 Lsolar), the spike is
definitely placed among AGNs by current diagnostics based on the emission line
intensity ratios, being just on the borderline between Seyferts and LINERs.
Line profiles are very broad, and both permitted and forbidden lines are best
modelled with a combination of broad and narrow components, with FWHM of ~3000
km s^-1 and ~700 km s^-1, respectively. This evidence argues for the variable
central spike being produced by a modest accretion event onto a central massive
black hole (BH), with the accreted material having possibly being stripped from
a a star in a close fly by with the BH. The 1996 broad Halpha luminosity of
this mini-AGN is ~5.6*10^37 erg s^-1, about a factor of two less than that of
the nucleus of NGC 4395, heretofore considered to be the faintest known AGN.Comment: 40 pages, LaTeX, with 12 PostScript figures. Accepted for publication
in the Astrophysical Journa
Exploring taboo issues in professional sport through a fictional approach
While the need to consider life course issues in elite sport research and practice is increasingly recognised, some experiences still seem to be considered too dangerous to explore. Consequently, stories of these experiences are silenced and the ethical and moral questions they pose fail to be acknowledged, understood or debated. This paper presents an ethnographic fiction through which we explore a sensitive set of experiences that were uncovered during our research with professional sportspeople. Through a multiâlayered reconstruction, the story reveals the complex, but significant, relationships that exist between identity, cultural narratives and embodied experiences. After the telling we consider how the story has stimulated reflective practice among students, researchers and practitioners. While there are risks involved in writing and sharing taboo stories, the feedback we have received suggests that storytelling can be an effective pedagogical tool in education and professional development
Suppressing a Blocked Balance Recovery Step: A Novel Method to Assess an Inhibitory Postural Response
Stepping to recover balance is an important way we avoid falling. However, when faced with obstacles in the step path, we must adapt such reactions. Physical obstructions are typically detected through vision, which then cues step modification. The present study describes a novel method to assess visually prompted step inhibition in a reactive balance context. In our task, participants recovered balance by quickly stepping after being released from a supported forward lean. On rare trials, however, an obstacle blocked the stepping path. The timing of vision relative to postural perturbation was controlled using occlusion goggles to regulate task difficulty. Furthermore, we explored step suppression in our balance task related to inhibitory capacity measured at the hand using a clinically feasible handheld device (ReacStick). Our results showed that ReacStick and step outcomes were significantly correlated in terms of successful inhibition (r = 0.57) and overall reaction accuracy (r = 0.76). This study presents a novel method for assessing rapid inhibition in a dynamic postural context, a capacity that appears to be a necessary prerequisite to a subsequent adaptive strategy. Moreover, this capacity is significantly related to ReacStick performance, suggesting a potential clinical translation
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