Alaska Natives and American Laws

In this thesis we focus on the issue of crowdfunding and especially how a project relates to and embraces its community. While a lot of related research focus on what makes people give, our research instead delve into whether a creator looks upon the sponsors as something more than just a financial resource. To manage this task we used a triangular perspective consisting of a case study, a questionnaire and a netnographic study. The goal was to gain the perspectives of creators, crowdfunding platforms and sponsors on how the communication between the community and the project works and can be improved.        The three crowdfunding platforms we reviewed (Kickstarter, IndieGoGo, Rockethub) all had fairly similar models on how to attract sponsors and make them involved in the project, while the questionnaire and netnographic study demonstrated how a community could contribute in different ways. Based on our results we draw the conclusion that a project can be successful without embracing the creative qualities of its sponsors but doing so also is a waste of a great asset to both current and future projects.

Recombinant Simian Varicella Virus-Simian Immunodeficiency Virus Vaccine Induces T and B Cell Functions and Provides Partial Protection against Repeated Mucosal SIV Challenges in Rhesus Macaques

HIV vaccine mediated efficacy, using an expanded live attenuated recombinant varicella virus-vectored SIV rSVV-SIVgag/env vaccine prime with adjuvanted SIV-Env and SIV-Gag protein boosts, was evaluated in a female rhesus macaques (RM) model against repeated intravaginal SIV challenges. Vaccination induced anti-SIV IgG responses and neutralizing antibodies were found in all vaccinated RMs. Three of the eight vaccinated RM remained uninfected (vaccinated and protected, VP) after 13 repeated challenges with the pathogenic SIVmac251-CX-1. The remaining five vaccinated and infected (VI) macaques had significantly reduced plasma viral loads compared with the infected controls (IC). A significant increase in systemic central memory CD4+ T cells and mucosal CD8+ effector memory T-cell responses was detected in vaccinated RMs compared to controls. Variability in lymph node SIV-Gag and Env specific CD4+ and CD8+ T cell cytokine responses were detected in the VI RMs while all three VP RMs had more durable cytokine responses following vaccination and prior to challenge. VI RMs demonstrated predominately SIV-specific monofunctional cytokine responses while the VP RMs generated polyfunctional cytokine responses. This study demonstrates that varicella virus-vectored SIV vaccination with protein boosts induces a 37.5% efficacy rate against pathogenic SIV challenge by generating mucosal memory, virus specific neutralizing antibodies, binding antibodies, and polyfunctional T-cell responses

Arbetsknivar : En funktionsanalys av knivar från Birkas Garnison

This paper deals with knives excavated in the Birka Garrison between 1997 and 2004, in a selection of 100 knives out of approximately 400. The aim is to measure and analyze the material to find out if certain elements in design points to a specific craft. Two groups of knifeblades can be seen, one with a convex bevel and one with a flat bevel of the blade. Considering osteological evidence, historical sources, and the main suitabillity of the knives, it is concluded that some of the flat beveled knives may have been used for crafting leather and fur, whereas the convex beveled knives are of an allround type