85 research outputs found
SYNERGISTIC EFFECT OF SILVER NANOPARTICLES WITH DOXYCYCLINE AGAINST KLEBSIELLA PNEUMONIA
Objective: Green synthesis, characterization of silver nanoparticles (AgNPs) and study of the synergistic effect of AgNPs with antibiotic doxycycline against Klebsiella pneumonia.Methods: AgNps were synthesized from bacteria isolated from samples obtained from petroleum soil. After characterization of the nanoparticles, the antibacterial activity of the nanoparticle was studied, and simultaneously the same nanoparticle was used in combination with doxycycline antibiotic.Results: It was observed that compared to the effects of AgNps and antibiotic alone, the collective effect on both of them was more evident, which indicate the synergistic effect of the two components.Conclusion: These findings highlight the potential for AgNPs to enhance the activity of doxycycline antibiotic against Klebsiella pneumonia infections.Keywords: Silver nanoparticle, Green Synthesis, Klebsiella Pneumonia, Doxycyclin
Initial‐valued first‐order fuzzy differential equation in Bi‐level inventory model with fuzzy demand
In the present paper, two methods for the solution of an initial valued first ordered fuzzy differential equation are presented and applied in a fuzzy EOQ model. The constructed model is a bi‐level inventory problem involving wholesaler‐retailers‐customers. The wholesaler buys and sells the item instantaneously to several retailers. In the next level, the retailers sell the units to customers with a time dependent imprecise demand, which introduce the fuzzy nature in the differential equation. The selling price of the item is a step‐wise time dependent decreasing function. The fuzzy objectives are transformed into crisp one following fuzzy extension principle and centroid formula. The model is illustrated through Interactive Fuzzy Decision Making (IFDM) and Multi Objective Genetic Algorithm (MOGA) and the results from two methods are compared.
First Published Online: 14 Oct 201
N-(6-{2-[6-(2,2-Dimethylpropanamido)-2-pyridyl]ethyl}-2-pyridyl)-2,2-dimethylpropanamide
The title compound, C22H30N4O2, lies about a crystallographic inversion center. The whole molecule is disordered over two positions with a refined occupancy ratio of 0.636 (10):0.364 (10). The pyridine rings are approximately planar, with maximum deviations of 0.033 (10) and 0.063 (17) Å for the major and minor components, respectively. The mean planes of the pyridine rings form dihedral angles of 17 (2)° in the major component and 18 (2)° in the minor component with the respective formamide groups attached to them. In the crystal packing, intermolecular N—H⋯O and C—H⋯O hydrogen bonds link the molecules into two-dimensional networks parallel to the ab plane
2,7-Dimethyl-1,8-naphthyridine
The asymmetric unit of the title compound, C10H10N2, contains one half-molecule with the two shared C atoms lying on a twofold rotation axis. The 1,8-naphthyridine is almost planar with a dihedral angle of 0.42 (3)° between the fused pyridine rings. In the crystal, molecules are linked into infinite chains along the c axis by intermolecular C—H⋯N hydrogen bonds, generating R
2
2(8) ring motifs. In addition, the crystal structure is further stabilized by C—H⋯π interactions
Quinoxaline-2-carbonitrile
In the title compound, C9H5N3, the quinoxaline ring is essentially planar, with a maximum deviation of 0.012 (1) Å. Short intermolecular distances between the centroids of the 2,3-dihydropyrazine and benzene rings [3.6490 (5) Å] indicate the existence of π⋯π interactions. In the crystal packing, the molecules are linked via two pairs of intermolecular C—H⋯N interactions, forming R
2
2 (8) and R
2
2 (10) ring motifs; these molecules are further linked into a two-dimensional network parallel to (1 0 2) via another C–H⋯N interaction
N-(6-Bromomethyl-2-pyridyl)acetamide
The title acetamide compound, C8H9BrN2O, crystallizes with three crystallographically independent molecules (A, B and C) in the asymmetric unit. In molecule A, the mean plane through the acetamide unit is inclined at a dihedral angle of 4.40 (11)° with respect to the pyridine ring [10.31 (12) and 2.27 (11)°, respectively, for molecules B and C]. In the crystal structure, molecules are interconnected into sheets parallel to the ac plane by N—H⋯O, C—H⋯Br, C—H⋯O and C—H⋯N hydrogen bonds. The structure is further stabilized by weak intermolecular C—H⋯π interactions
Experiences from Nation-wide adoption of Satellite based Near Real Time Forest fire alerts to improve forest fire management in India
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