Plasma proteins production and excretion in diabetic nephropathy in type II diabetic patients

Diabetic nephropathy is the leading cause of chronic renal disease and a major cause of cardiovascular mortality in both developed and developing countries. In type II diabetes patients with normoalbuminuria, fibrinogen production is increased, whereas that of albumin is normal. It is not known whether hepatic albumin production in albuminuric type II diabetes patients is also increased, and whether fibrinogen production is further increased in these patients. Knowledge of these potential relationships is important to understand both the mechanistic associations between albuminuria and hyperfibrinogenaemia. Therefore, this study was designed to measure fibrinogen and albumin concentrations in patients with type II diabetes who had normal or increased urinary albumin excretion. Subjects, materials, and methods: Plasma albumin, and fibrinogen concentrations and urinary albumin are measured in macroalbuminuric diabetic patients (n=16), microalbuminuric diabetic patients (n=16), and healthy controls (n=8).Results: A direct relationship was found between albuminuria and albumin concentration (r=0.59, p<0.05). Direct relationship also found between albuminuria and fibrinogen concentration (r=0.65, p<0.002), and fibrinogen pool (r=0.66, p<0.002).Conclusions: this study demonstrates that albumin and fibrinogen levels are increased in macroalbuminuric type II diabetes subjects compared with type II diabetes patients with microalbuminuria and healthy subjects , showing an upregulation of hepatic secretory proteins in this clinical condition. Such an upregulation seems to be responsible for the relative hyperfibrinogenaemia observed in the albuminuric diabetic patients.Keywords: Plasma proteins, Diabetic nephropathy, Diabetes mellitus

Dental caries, oral health and life style variables among school children in Qatar

Background: Effective delivery of dental services must be based on reliable information regarding the prevalence and severity of disease in the target population. Evaluation of the various factors known to influence the severity and progression of disease is essential for health policy makers to promote oral health resources and address oral health needs. Objective: The overall aim of this research is to describe the situation of dental caries and investigate the associations of level of oral health knowledge, teeth irregularity, BMI and other life style variables (TV viewing, internet use, passive smoking and dietary habits) with dental caries, including the impact of socio-demographic factors amongst school children in Qatar. Materials and methods: A cross-sectional study was conducted in Qatar from October 2011 to March 2012. A total of 2,113 children aged 12-14 years were randomly selected from 16 schools from different areas. Clinical examination was conducted by three calibrated examiners using World Health Organization criteria for diagnosing dental caries. Teeth irregularity was determined clinically according to a method described by Björk et al (1964). A pre-tested and structured questionnaire was used to assess oral health knowledge and life style data. Data analyses were performed. Results: The mean decayed, missing and filled teeth index values was 4.62 (±3.2), 4.79 (±3.5), and 5.5 (±3.7), respectively, for the 12, 13 and 14 year old children. The caries prevalence was 85%. The mandibular incisors and canines were least likely to be affected by dental caries, while maxillary and mandibular molars were the most frequently attacked by dental caries. Of the total sample, only one quarter reported a high level of oral health knowledge. There were more incidences of teeth crowding (44.1%) than teeth spacing (9.5%). The overall prevalence of underweight, overweight, and obesity was 5%, 10%, and 5% respectively. Almost half of the children spent > two hours watching television and 46% spent > two hours using internet. Approximately 35.8% of children had exposure to passive smoking. Concerning dietary habits, 99.4% of children consumed sugar containing snacks in between meals. Approximately 65% consumed sugar containing snacks within one hour of bed time. Almost 49.1% skipped eating breakfast regularly and 22.7% skipped eating lunch regularly. Around 83.8% consumed diary snacks in between meals. Overall, 74.2% drank tea in-between meals and 80.1% chewed gum in-between meals. All variables were affected by socio-demographic factors, but significant differences were found in female children in that they were more at risk to dental caries than male children. Also, children who resided in semi-urban areas were more at risk to dental caries than children who resided in urban areas. The occurrence of dental caries is significantly associated with the level of oral health knowledge, teeth irregularity, and other life style variables. Conclusion: The need to reduce sedentary behaviors and to promote a more active and healthy lifestyle is becoming increasingly essential in Qatar. Implementation of a community-based preventive oral health programs on a healthy diet and practices of adequate oral hygiene should be promoted in schools through integration into the school curriculum and services to combat the growing problem of dental caries

An Aggregate Scalable Scheme for Expanding the Crossbar Switch Network; Design and Performance Analysis

New computer network topology, called Penta-S, is simulated. This network is built of cross bar switch modules. Each module connects 32 computer nodes. Each node has two ports, one connects the node to the crossbar switch module and the other connects the node to a correspondent client node in another module through a shuffle link. The performance of this network is simulated under various network sizes, packet lengths and loads. The results are compared with those obtained from Macramé project for Clos multistage interconnection network and 2D-Grid network. The throughput of Penta-S falls between the throughput of Clos and the throughput of 2D-Grid networks. The maximum throughput of Penta-S was obtained at packet length of 128 bytes. Also the throughput grows linearly with the network size. On the opposite of Clos and 2D-Grid networks, the per-node throughput of Penta-S improves as the network size grows. The per-packet latency proved to be better than that of Clos network for large packet lengths and high loads. Also the packet latency proved to be nearly constant against various loads. The cost-efficiency of Penta-S proved to be better than those of 2D-Grid and Clos networks for large number of nodes (>200 nodes in the case of 2D-Grid and >350 nodes in the case of Clos).On the opposite of other networks, the cost-efficiency of Penta-S grows as its size grows. So this topology suits large networks and high traffic loads

Influence of Swimming Deprivation on Behavior, Performance and some Blood Parameters of Muscovy Ducks

This experiment was done to determine the effect of swimming deprivation on drinking behaviour, feather pecking behavior, feed consumption, weight gain, feed conversion ratio, live body weight, slaughter weight, carcass weight and dressing percentage, serum corticosterone, triiodothyronine (T3) and tetraiodothyronine (T4) of Muscovy ducks. Two groups were used; the first one is the control group fed on basal diet with free access to swimming pond, and the second fed on basal diet without access to swimming pond. The previous parameters were recorded daily or weekly during the experiment or after slaughtering for collecting blood parameters. The results explained that, there was an insignificant decrease in drinking behavior and significant increase in feather pecking. However, there was an insignificant decrease in feed consumption, live body weight, feed conversion, weight gain, dressing percentage, liver weight and serum corticosterone level. There was an insignificant decrease in T3 and T4 level and significant increase in feather pecking behaviour. It could be concluded that, swimming deprivation at the end of the fattening period of ducks had an adverse effect on some duck behaviors but it have no significant effect on improvement of performance parameters and carcass characters

Energy-Aware WiFi Network Selection via Forecasting Energy Consumption

Covering a wide area by a large number of WiFi networks is anticipated to become very popular with Internet-of-things (IoT) and initiatives such as smart cities. Such network configuration is normally realized through deploying a large number of access points (APs) with overlapped coverage. However, the imbalanced traffic load distribution among different APs affects the energy consumption of a WiFi device if it is associated to a loaded AP. This research work aims at predicting the communication-related energy that shall be consumed by a WiFi device if it transferred some amount of data through a certain selected AP. In this paper, a forecast of the energy consumption is proposed to be obtained using an algorithm that is supported by a mathematical model. Consequently, the proposed algorithm can automatically select the best WiFi network (best AP) that the WiFi device can connect to in order to minimize energy consumption. The proposed algorithm is experimentally validated in a realistic lab setting. The observed performance indicates that the algorithm can provide an accurate forecast to the energy that shall be consumed by a WiFi transceiver in sending some amount of data via a specific AP

Force feeding as a Stress Factor on Muscovy Ducks

The experiment was done to determine the effects of force feeding on drinking, panting behaviors, feed consumption, weight gain, feed conversion ratio, live body weight, slaughter weight, carcass weight and dressing percentage, serum corticosterone, triiodothyronine (T3) and tetraiodothyronine (T4) of Muscovy ducks. Two groups were used; the first one was the control group, which fed on basal diet only and the second group was force fed by grabbing the neck, and a metal or plastic tube 8 to 12 inches long was inserted down the esophagus. Ducklings were forced to ingest a greater amount of food than what they would eat voluntarily. The previous parameters were recorded daily or weekly during the experiment or after slaughtering. Blood samples for separation of serum were collected after slaughtering. The results explained that, there was an insignificant increase in drinking behavior. However, there was a significant increase in feed consumption, live body weight, feed conversion, weight gain, dressing percentage, panting behavior, liver weight and serum corticosterone level while there was a significant decrease in T3 and T4 level. It could be concluded that, force feeding at the end of the fattening period of ducks had adverse effect on some duck behaviors and some blood parameters but led to improvement in performance parameters and carcass characters