2,107 research outputs found

    Male mice emit distinct ultrasonic vocalizations when the female leaves the social interaction arena.

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    Adult male mice emit large number of complex ultrasonic vocalizations (USVs) when interacting with adult females. Call numbers and call categories differ greatly among inbred mouse strains. Little is known about USV emissions when the social partner departs. To investigate whether call repertoires and call rates are different when the male is interacting with a female and after the removal of the female, we designed a novel male-female social interaction test in which vocalizations were recorded across three phases. During phase 1, the male subject freely interacts with an unfamiliar estrus female mouse in a clean cage for 5 min. During phase 2, the female is removed while the male remains in the cage for 3 min. During phase 3, the same female is returned to the cage to rejoin the male subject mouse for 3 min. C57BL/6J (B6), FVB.129P2-Pde6b(+) Tyr(c-ch)/Ant (FVB), and BTBR T+ tf/J (BTBR) male subject mice were tested in this paradigm. All three strains emitted USVs during their initial interaction with the female partner. When the female was reintroduced in phase 3, numbers of USVs were similar to the initial introductory phase 1. Strain comparisons indicated fewer calls in pairs of BTBR males and stimulus females than in pairs of B6 males and stimulus females and pairs of FVB males and stimulus females. In the absence of the female, all FVB males vocalized, while only one third of B6 males and one third of BTBR males vocalized. In all three strains, changes in call category repertoires were detected after the female was removed. Call categories reverted to the phase 1 pattern when the female was returned in phase 3. Present findings indicate that males of commonly used inbred strains emit USVs when a partner female leaves the testing arena, suggesting that removing a salient social stimulus may be a unique approach to elicit USVs from mice. Our three-phase paradigm may also be useful for studying attention to social cues, and qualitative differences in vocalizations when a social partner is present vs. suddenly absent

    Sandpiles, spanning trees, and plane duality

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    Let G be a connected, loopless multigraph. The sandpile group of G is a finite abelian group associated to G whose order is equal to the number of spanning trees in G. Holroyd et al. used a dynamical process on graphs called rotor-routing to define a simply transitive action of the sandpile group of G on its set of spanning trees. Their definition depends on two pieces of auxiliary data: a choice of a ribbon graph structure on G, and a choice of a root vertex. Chan, Church, and Grochow showed that if G is a planar ribbon graph, it has a canonical rotor-routing action associated to it, i.e., the rotor-routing action is actually independent of the choice of root vertex. It is well-known that the spanning trees of a planar graph G are in canonical bijection with those of its planar dual G*, and furthermore that the sandpile groups of G and G* are isomorphic. Thus, one can ask: are the two rotor-routing actions, of the sandpile group of G on its spanning trees, and of the sandpile group of G* on its spanning trees, compatible under plane duality? In this paper, we give an affirmative answer to this question, which had been conjectured by Baker.Comment: 13 pages, 9 figure

    Case studies emphasising the difficulties in the diagnosis and management of alveolar echinococcosis in rural China

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    <p>Abstract</p> <p>Background</p> <p>Human alveolar echinococcosis (AE) is caused by the accidental ingestion of the eggs of the fox tapeworm <it>Echinococcus multilocularis</it>. AE occurs frequently in rural western China due to the poor levels of hygiene, the close contact of people with dogs, and the lack of appropriate facilities for the correct and rapid diagnosis of the disease.</p> <p>Findings</p> <p>We describe a case of a patient with hepatic AE, and AE metastases of the brain. She was mistakenly diagnosed with suspected undifferentiated metastatic cancer of the liver and brain, and with a pulmonary bacterial infection, but was subsequently correctly diagnosed during a follow-up field survey for echinococcosis. The diagnosis of brain AE was confirmed by pathological examination of tissue biopsies removed during neurosurgery. We also briefly describe other symptomatic and asymptomatic AE cases, identified by chance, likely due to the inadequate facilities available in rural communities in China for AE diagnosis and management, since the rapid and accurate diagnosis of metastatic AE requires a high level of expertise in the appropriate diagnostic procedures.</p> <p>Conclusions</p> <p>This report highlights the necessity for an upgrade in the diagnosis, treatment, prevention and control of AE in rural China.</p

    2009-2010 Dean\u27s Showcase No. 3

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    https://spiral.lynn.edu/conservatory_deansshowcase/1031/thumbnail.jp

    Cylindrical illumination with angular coupling for whole-prostate photoacoustic tomography

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    Current diagnosis of prostate cancer relies on histological analysis of tissue samples acquired by biopsy, which could benefit from real-time identification of suspicious lesions. Photoacoustic tomography has the potential to provide real-time targets for prostate biopsy guidance with chemical selectivity, but light delivered from the rectal cavity has been unable to penetrate to the anterior prostate. To overcome this barrier, a urethral device with cylindrical illumination is developed for whole-prostate imaging, and its performance as a function of angular light coupling is evaluated with a prostate-mimicking phantom

    X-ray scattering from surfaces: discrete and continuous components of roughness

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    Incoherent surface scattering yields a statistical description of the surface, due to the ensemble averaging over many independently sampled volumes. Depending on the state of the surface and direction of the scattering vector relative to the surface normal, the height distribution is discrete, continuous, or a combination of the two. We present a treatment for the influence of multimodal surface height distributions on Crystal Truncation Rod scattering. The effects of a multimodal height distribution are especially evident during in situ monitoring of layer-by-layer thin-film growth via Pulsed Laser Deposition. We model the total height distribution as a convolution of discrete and continuous components, resulting in a broadly applicable parameterization of surface roughness which can be applied to other scattering probes, such as electrons and neutrons. Convolution of such distributions could potentially be applied to interface or chemical scattering. Here we find that this analysis describes accurately our experimental studies of SrTiO3 annealing and homoepitaxial growth.Comment: 15 pages, 7 figure
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