A Solution to the Flowgraphs Case Study using Triple Graph Grammars and eMoflon

After 20 years of Triple Graph Grammars (TGGs) and numerous actively maintained implementations, there is now a need for challenging examples and success stories to show that TGGs can be used for real-world bidirectional model transformations. Our primary goal in recent years has been to increase the expressiveness of TGGs by providing a set of pragmatic features that allow a controlled fallback to programmed graph transformations and Java. Based on the Flowgraphs case study of the Transformation Tool Contest (TTC 2013), we present (i) attribute constraints used to express complex bidirectional attribute manipulation, (ii) binding expressions for specifying arbitrary context relationships, and (iii) post-processing methods as a black box extension for TGG rules. In each case, we discuss the enabled trade-off between guaranteed formal properties and expressiveness. Our solution, implemented with our metamodelling and model transformation tool eMoflon (www.emoflon.org), is available as a virtual machine hosted on Share.Comment: In Proceedings TTC 2013, arXiv:1311.753

Spatial discretization of restricted group algebras

We consider spatial discretizations by the finite section method of the restricted group algebra of a finitely generated discrete group, which is represented as a concrete operator algebra via its left-regular representation. Special emphasis is paid to the quasicommutator ideal of the algebra generated by the finite sections sequences and to the stability of sequences in that algebra. For both problems, the sequence of the discrete boundaries plays an essential role. Finally, for commutative groups and for free non-commutative groups, the algebras of the finite sections sequences are shown to be fractal

In-medium Pion-Pion Interaction and Chiral Symmetry Restoration

We discuss medium modifications of the unitarized pion-pion interaction in the nuclear medium. We incorporate both the effects of chiral symmetry restoration and the influence of collective nuclear pionic modes, originating from the p-wave coupling of the pion to delta-hole configurations. We show how the resulting strong enhancement of the sigma-meson spectral function is related to large fluctuations of the condensate associated with the partial restoration of chiral symmetry.Comment: 8 pages, 3 Postscript figures, contribution to the `International Workshop XXVIII on Gross Properties of Nuclei and Nuclear Excitations', Hirschegg, Austria, January 16-22 200

Alleinerziehende unter Druck. Rechtliche Rahmenbedingungen, finanzielle Lage und Reformbedarf = Single parents under pressure. Legal framework, financial situation and need for reform

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Using evidence, expert opinion and epidemiological model to understand pathways to survival and mortality:The Pathways to Survival (PATHS) Tool

BACKGROUND: The reasons why episodes of illness can lead to fatal outcomes in affected persons in low resource settings are numerous and complex. A tool that allows policy makers to better understand those complexities could be useful to improve success of programmes that are implemented globally to reduce mortality. METHODS: We developed a “Pathways to Survival” (PATHS) tool: an epidemiological model using decision trees, available evidence and expert opinion. PATHS visualises the “architecture” of mortality in the population by following the entire population cohort over a certain period of time. It explains how initially healthy persons progress through health systems to lethal outcomes at the end of the specified time period. We developed an illustrative example based on the 136 million newborns and an estimated 907 000 deaths from newborn sepsis in the year 2008. This allowed us to develop an epidemiological model that described pathways to deaths from neonatal sepsis globally in 2010. RESULTS: The model described the “status quo’ situation in 2010 with 907 000 deaths to allow an assessment of the potential impact and feasibility of different interventions and programmes at various level of health systems in reducing this cause of mortality. A useful model should incorporate both a ‘horizontal’ and a ‘vertical’ component. The ‘horizontal’ would track the progress of all neonates globally through time, ie, their first 28 days of life, and separate them into different ‘pathways’ every time a change in their risk of dying from neonatal infection occurs because of their specific contextual circumstances. The ‘vertical’ would track their position within the health systems of their countries and separate them into different categories based on the ability of health system to intervene and reduce their risk of dying. Based on those requirements, PATHS tool was developed which is based on decision trees where different “branches” of the trees are associated with varying case-fatality rates. CONCLUSIONS: The application of the PATHS tool on the example of newborn sepsis revealed that novel diagnostic tests could save many lives, so we should continue to invest in them to improve their validity, deliverability and affordability. However, PATHS showed that investments in better diagnostics have limited impact unless they are coupled with improvements of the context. Programs for parental education improve compliance and care seeking. Promoting legislation change to empower community health workers (CHWs) to actively engage in prevention, diagnosis and care also makes a difference, as well as programs for training CHWs to use diagnostic tests and administer treatments correctly. Care-seeking behaviour can also be improved through programs of conditional cash transfers. Finally, PATHS demonstrated that improving access to primary and secondary health care for everyone is the most powerful contextual change

Unified theory of bound and scattering molecular Rydberg states as quantum maps

Using a representation of multichannel quantum defect theory in terms of a quantum Poincar\'e map for bound Rydberg molecules, we apply Jung's scattering map to derive a generalized quantum map, that includes the continuum. We show, that this representation not only simplifies the understanding of the method, but moreover produces considerable numerical advantages. Finally we show under what circumstances the usual semi-classical approximations yield satisfactory results. In particular we see that singularities that cause problems in semi-classics are irrelevant to the quantum map

Towards a Flexible Intra-Trustcenter Management Protocol

This paper proposes the Intra Trustcenter Protocol (ITP), a flexible and secure management protocol for communication between arbitrary trustcenter components. Unlike other existing protocols (like PKCS#7, CMP or XKMS) ITP focuses on the communication within a trustcenter. It is powerful enough for transferring complex messages which are machine and human readable and easy to understand. In addition it includes an extension mechanism to be prepared for future developments.Comment: 12 pages, 0 figures; in The Third International Workshop for Applied PKI (IWAP2004

Emollient enhancement of the skin barrier from birth offers effective atopic dermatitis prevention

BackgroundAtopic dermatitis (atopic eczema) is a chronic inflammatory skin disease that has reached epidemic proportions in children worldwide and is increasing in prevalence. Because of the significant socioeconomic effect of atopic dermatitis and its effect on the quality of life of children and families, there have been decades of research focused on disease prevention, with limited success. Recent advances in cutaneous biology suggest skin barrier defects might be key initiators of atopic dermatitis and possibly allergic sensitization.ObjectiveOur objective was to test whether skin barrier enhancement from birth represents a feasible strategy for reducing the incidence of atopic dermatitis in high-risk neonates.MethodsWe performed a randomized controlled trial in the United States and United Kingdom of 124 neonates at high risk for atopic dermatitis. Parents in the intervention arm were instructed to apply full-body emollient therapy at least once per day starting within 3 weeks of birth. Parents in the control arm were asked to use no emollients. The primary feasibility outcome was the percentage of families willing to be randomized. The primary clinical outcome was the cumulative incidence of atopic dermatitis at 6 months, as assessed by a trained investigator.ResultsForty-two percent of eligible families agreed to be randomized into the trial. All participating families in the intervention arm found the intervention acceptable. A statistically significant protective effect was found with the use of daily emollient on the cumulative incidence of atopic dermatitis with a relative risk reduction of 50% (relative risk, 0.50; 95% CI, 0.28-0.9; P = .017). There were no emollient-related adverse events and no differences in adverse events between groups.ConclusionThe results of this trial demonstrate that emollient therapy from birth represents a feasible, safe, and effective approach for atopic dermatitis prevention. If confirmed in larger trials, emollient therapy from birth would be a simple and low-cost intervention that could reduce the global burden of allergic diseases