7,520 research outputs found

    Review of the book CLIL activities : a resource for subject and language teachers (with CD-ROM)

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    CLIL Activities may be taken as a handbook focused on practice as more than half of its pages do offer wide-ranging activities. The authors state that the book is targeted at subject and language teachers probably with the intention of showing that both content and language are equally important and interrelated

    Novel role for the LKB1 pathway in controlling monocarboxylate fuel transporters

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    A question preoccupying many researchers is how signal transduction pathways control metabolic processes and energy production. A study by Jang et al. (Jang, C., G. Lee, and J. Chung. 2008. J. Cell Biol. 183:11–17) provides evidence that in Drosophila melanogaster a signaling network controlled by the LKB1 tumor suppressor regulates trafficking of an Sln/dMCT1 monocarboxylate transporter to the plasma membrane. This enables cells to import additional energy sources such as lactate and butyrate, enhancing the repertoire of fuels they can use to power vital activities

    Utility Design for Distributed Resource Allocation -- Part I: Characterizing and Optimizing the Exact Price of Anarchy

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    Game theory has emerged as a fruitful paradigm for the design of networked multiagent systems. A fundamental component of this approach is the design of agents' utility functions so that their self-interested maximization results in a desirable collective behavior. In this work we focus on a well-studied class of distributed resource allocation problems where each agent is requested to select a subset of resources with the goal of optimizing a given system-level objective. Our core contribution is the development of a novel framework to tightly characterize the worst case performance of any resulting Nash equilibrium (price of anarchy) as a function of the chosen agents' utility functions. Leveraging this result, we identify how to design such utilities so as to optimize the price of anarchy through a tractable linear program. This provides us with a priori performance certificates applicable to any existing learning algorithm capable of driving the system to an equilibrium. Part II of this work specializes these results to submodular and supermodular objectives, discusses the complexity of computing Nash equilibria, and provides multiple illustrations of the theoretical findings.Comment: 15 pages, 5 figure

    Heat current rectification and mobility edges

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    We investigate how the presence of a single-particle mobility edge in a system can generate strong heat current rectification. Specifically, we study a quadratic bosonic chain subject to a quasi-periodic potential and coupled at its boundaries to spin baths of differing temperature. We find that rectification increases by orders of magnitude depending on the spatial position in the chain of localized eigenstates above the mobility edge. The largest enhancements occur when the coupling of one bath to the system is dominated by a localized eigenstate, while the other bath couples to numerous delocalized eigenstates. By tuning the parameters of the quasi-periodic potential it is thus possible to vary the amplitude, and even invert the direction, of the rectification.Comment: 5+3 pages 4+4 figure

    General static spherically symmetric solutions in Horava gravity

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    We derive general static spherically symmetric solutions in the Horava theory of gravity with nonzero shift field. These represent "hedgehog" versions of black holes with radial "hair" arising from the shift field. For the case of the standard de Witt kinetic term (lambda =1) there is an infinity of solutions that exhibit a deformed version of reparametrization invariance away from the general relativistic limit. Special solutions also arise in the anisotropic conformal point lambda = 1/3.Comment: References adde

    Numerical investigation of novel microwave applicators based on zero-order mode resonance for hyperthermia treatment of cancer

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    This paper characterizes three novel microwave applicators based on zero-order mode resonators for use in hyperthermia treatment of cancer. The radiation patterns are studied with numerical simulations in muscle tissue-equivalent model at 434 MHz. The relative performance of the applicators is compared in terms of reflection coefficient, current distribution, power deposition (SAR) pattern, effective field size in 2D and 3D tissue volumes, and penetration depth. One particular configuration generated the most uniform SAR pattern, with 25% SAR covering 84 % of the treatment volume extending to 1 cm depth under the aperture, while remaining above 58% coverage as deep as 3 cm under the aperture. Recommendations are made to further optimize this structure

    Preferential Sampling of Elastic Chains in Turbulent Flows

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    A string of tracers, interacting elastically, in a turbulent flow is shown to have a dramatically different behaviour when compared to the non-interacting case. In particular, such an elastic chain shows strong preferential sampling of the turbulent flow unlike the usual tracer limit: an elastic chain is trapped in the vortical regions and not the straining ones. The degree of preferential sampling and its dependence on the elasticity of the chain is quantified via the Okubo-Weiss parameter. The effect of modifying the deformability of the chain, via the number of links that form it, is also examined.Comment: 6 pages, 4 figure
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