Non-invasive fitness assessment in horses:Integrating wearables and machine learning

The field of human sports has advanced significantly with the integration of machine learning and sensors for performance analysis. However, sport horses have not benefited equally from technological advancements due to their inability to provide feedback, such as verbal expressions of fatigue or difficulty.Veterinarians and researchers traditionally interpret equine well-being through methods like verbal encouragement, facial expressions, and blood sample analysis. These methods are either subjective or invasive, causing stress and disruption during training. Accurate and reliable fitness parameter values are essential to avoid overtraining and injuries, necessitating a more effective and less intrusive approach.This PhD thesis aims to revolutionize sport horse training by using wearable inertial sensors and state-of-the-art machine learning to enhance performance and prevent injuries. The study is divided into nine chapters, each contributing to the overall goal of improving equine fitness and well-being.Each chapter begins with a literature review to identify gaps and challenges in equine fitness and performance. Inertial sensors were chosen for their ability to capture a wide range of real-time motion data. The sensors were placed on various parts of the horse’s body, including the head, neck, shoulders, back, and legs. Data were collected during various training and competition scenarios to evaluate the system's effectiveness.The results demonstrated that the system could accurately capture and analyze a broad spectrum of motion data, providing valuable insights for trainers and riders. This technology can improve fitness and prevent injuries in sport horses by offering practical tools for assessing equine fitness outside of laboratory settings.This thesis makes significant contributions to equine research by leveraging wearable sensor technology and machine learning to enhance our understanding of equine fitness, performance, and well-being. The findings are valuable not only to the scientific community but also to the broader equestrian world, promoting the welfare of sport horses and the sustainability of the equestrian industry

ESSAYS ON U.S. BEEF MARKETS

This dissertation includes three essays on U.S. beef market. Each essay has looked at this market from a different point of view. The first essay investigates the price adjustment along the different levels of this market. The second essay discusses the impact of food safety incidents on export levels in this market. The third essay considers the environmental loading of U.S. beef market. A summary of each article is as follows. The first essay (chapter 2) analyzes price adjustment of the U.S. beef sector with a focus on the Great Recession. To this purpose, the Vector Error Correction Model (VECM) and historical decomposition graphs are applied to monthly data. The results indicate that retail prices have lower speeds of adjustment than wholesale prices. Also, the magnitude of price adjustment in the presence of the Great Recession, as an exogenous shock, is different for each level of the U.S. beef market. It is concluded that, with respect to both the speed and magnitude of the price adjustment, the U.S. beef sector has an asymmetric price adjustment, pointing to the inefficiency of the U.S. beef supply chain. These results have welfare implications for U.S. beef consumers and producers. The primary objective of the second essay (chapter 3) is to quantify the impact of consumer awareness about beef safety on U.S. beef exports. To do that, an index is used to reflect consumer’s awareness about beef safety based on the publicized reports in the media. Quarterly panel data is applied to the top importing countries, Japan, South Korea, Mexico, and Canada for the period 2000-2016. Applying the gravity model, results show that a 0.8% reduction in U.S. beef exports arose from the foodborne-disease news. In addition, using impulse response functions derived from panel vector autoregressive (Panel VAR) estimation, results show that the negative impact of a shock in food safety news intensified after three quarters, and then diminished slowly over time. In order to regain consumers’ confidence and to compensate for the economic loss arising from a foodborne outbreak, bilateral cooperation among trade partners seems necessary. Investing in any scheme that minimizes the impact of food safety events, such as disease eradication programs, traceability systems, quality labeling, and third-party certification that conveys the safety message to consumers is suggested. The third essay (chapter 4) has two purposes. First, it quantifies the environmental loading of U.S. beef sector by calculating emission levels over the period 1970-2014. Beef cattle is one of the most emission-intensive sectors, which is responsible for 35% to 54% of total GHGs from livestock. Following International Panel on Climate Change (IPCC) guideline, this study identifies three sources of emissions, including enteric fermentation, manure management, and manure left on pastures. Second, it provides an understanding of consumption-environmental connection related to the beef industry using time series techniques. Finally, it is suggested that providing information to the public regarding livestock and climate change relationship would be beneficial. This knowledge might help to avoid the catastrophic consequences of climate change in the future

Metabolic Regulation of Cellular Signaling

Using the biochemically tractable Xenopus oocyte model system, we have previously characterized a novel metabolic regulation of cell death. We found that glucose-6-phosphate (G6P) via the pentose phosphate pathway leads to increased nicotinamide adenine dinucleotide phosphate (NADPH) levels, a subsequent increase in cytosolic acetyl-coenzyme A and activation of Ca2+/calmodulin-dependent protein kinase II (CaMKII). We recently identified coenzyme A (CoA), derived from the breakdown of acetyl-CoA, as the key metabolic signal that mediates a novel mechanism of calmodulindependent activation of CaMKII. CoA binds directly to the calmodulin (CaM) binding domain (CaMBD) of CaMKII resulting in its activation and downstream inhibitory phosphorylation of caspase-2, suppressing apoptosis. In this dissertation, we questioned whether there are other CaMBD containing proteins metabolically regulated by CoA. In an unbiased approach, CaM binding proteins were first isolated from Xenopus extract using a CaM-Sepharose column. Purified CaM binding proteins were then incubated with CoA-Sepharose in a second purification step and resolved by sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) and silver staining. The results indicate the presence of numerous CaM-binding proteins that also bind CoA and are thus potentially metabolically regulated. In a targeted approach, we tested the ability of aberrant glucose signaling to regulate the CaM-binding protein PI3K. We found that addition of G6P, mimicking aberrant glucose metabolism, or CoA to X. laevis egg extracts activated Akt in a phosphatidylinositol 3-kinase (PI3K), phosphoinositidedependent protein kinase 1(PDPK1)-dependent manner. Additionally, we show that CoA binds directly to and activates PI3K. These findings uncover a novel mechanism of PI3K activation by aberrant glucose metabolism and suggest a potentially unknown constitutive activation pathway of PI3K/Akt by aberrant glucose signaling

Trends and Factors Impacting Healthcare Charges and Length of Stay for Cholecystectomies: A New York State Population-based Analysis

Background: Gallbladder disease confers a significant economic toll on the United States healthcare system. This study aims to characterize current trends and features of the cholecystectomy population and identify factors that influence the length of stay and total charges. Methods: Case information was extracted for laparoscopic and open cholecystectomies from 2013-2016 using the New York Statewide Planning and Research Cooperative System (SPARCS) database. Descriptive, comparative, and multivariable linear regression analysis was conducted on 58,141 cases assessing age group, race, gender, admission presentation, surgical technique, insurance status, year of operation and severity of illness by the length of stay and total charges. Results: Of all procedures, 91.6% were laparoscopic, and 79.4% were emergent on admission. Total procedures trended down, while laparoscopic and emergent cases steadily increased (p<0.0001). Total charges increased during the study period, while the length of stay decreased (p<0.0001). Open and emergent procedures were associated with a higher cost and longer inpatient stays (p<0.0001). Open procedures were proportionally more common among elderly, male patients, and in elective cases (p<0.0001). Emergent presentation was more common in females, non-whites, and younger patients (p<0.0001). Regression model showed that male gender, open operation, Black race, and emergent presentation were independent predictors for a longer stay and greater total charges (p<0.0001). Medicare insurance predicted lower total charges but longer length of stay (p<0.0001). Conclusion: Race, insurance, procedure type, and patient presentation influence hospital charges and stays following cholecystectomy. Understanding these trends will allow policymakers and providers to limit the healthcare burden of cholecystectomy

World Literature: A Panacea for the Colonial Prejudice of English Literature

The present study is an attempt to discuss the importance of “World Literature” for English literary studies in universities and societies around the world. In this regard, this paper shall refer to the stances adopted by various thinkers against the colonial and ideological essence of the English literature in developing countries. In this part, references are made to postcolonial thinkers and the way they have exposed the barbaric nature of colonialism, in that it has, for decades, marginalized the culture and literature of other nations through cultural (neo)colonialism. The next part offers a brief introduction to the history of the emergence of “World Literature” and the ways in which it contributes to bridging the gap between nations across continents and ideological divides. The final section is devoted to a recapitulatory remark vis-à-vis the reorientation of the public’s eyes towards “World Literature” as a panacea for the colonial prejudice of English literature

Assembly, growth and conductive properties of tellurium nanorods produced by Rhodococcus aetherivorans BCP1

Tellurite (TeO32-) is a hazardous and toxic oxyanion for living organisms. However, several microorganisms can bioconvert TeO32- into the less toxic form of elemental tellurium (Te0). Here, Rhodococcus aetherivorans BCP1 resting (non-growing) cells showed the proficiency to produce tellurium-based nanoparticles (NPs) and nanorods (NRs) through the bioconversion of TeO32-, depending on the oxyanion initial concentration and time of cellular incubation. Te-nanostructures initially appeared in the cytoplasm of BCP1 cells as spherical NPs, which, as the exposure time increased, were converted into NRs. This observation suggested the existence of an intracellular mechanism of TeNRs assembly and growth that resembled the chemical surfactant-assisted process for NRs synthesis. The TeNRs produced by the BCP1 strain showed an average length (>700 nm) almost doubled compared to those observed in other studies. Further, the biogenic TeNRs displayed a regular single-crystalline structure typically obtained for those chemically synthesized. The chemical-physical characterization of the biogenic TeNRs reflected their thermodynamic stability that is likely derived from amphiphilic biomolecules present in the organic layer surrounding the NRs. Finally, the biogenic TeNRs extract showed good electrical conductivity. Thus, these findings support the suitability of this strain as eco-friendly biocatalyst to produce high quality tellurium-based nanomaterials exploitable for technological purposes

Low Tech, High Tech, Just the Right Tech: Find the Perfect Tools to Create Multimedia for Your Library

The purpose of this presentation is to share our techniques for creating easy to use tutorials for your library. Whether you serve a small academic community, or a large university, we hope to present ideas that work for your library. We will cover the basic pedagogy behind tutorial creation and use, and then present both licensed and open sourced tools for creating multimedia tutorials at all funding levels. Participants will be asked to participate in storyboarding exercise where they put together a learning object they can take back to their institution. Our goal is to demystify the tutorial creation process

A study of relation between comparative advantage indices of wheat and support policies by using econometrics approach

Comparative advantage is a term used to describe a production capability with low level output price and minimum opportunity costs. This study was done to evaluate the importance of maintaining comparative advantage for a strategic crop such as wheat in terms of changes and contributing factors over time. In this study data has been calculated and investigated by comparative advantage indices such as Net Social Profit and Domestic Resource Cost for the period of 1984-2010 in Iran. Following a stationary test and an econometrics model the Vector Error Correction Model (VECM) was applied to analyze the relation between guaranteed price policy, producer support estimate index and subsidies by comparative advantage indices. Results showed that as producer support is increased, comparative advantage decreased and the use of cheaper price inputs led to less competitiveness although the guaranteed price policy led to an improvement in scale advantage index, but had no positive effect on the efficiency advantage index. This study suggests that there is a need to perform investigations considering the relationship of cost and world market price and a change from direct support of the agricultural sector to indirect support in the form of structural support, and finally with the implementation of targeted subsidy policy, these multiple goals can be achieve