11 research outputs found

    Are we nearly there yet? Starts and stops on the road to use of polygenic scores

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    As technological advancements expand the accessibility and availability of molecular genetic data, excitement over the potential use of genetic risk scores also known as polygenic scores (PGS) or polygenic indices for disease prevention has grown. At the same time, however, the translation of PGS into healthcare and social settings raises a host of social, ethical, and clinically relevant questions

    Genetics and Education: Recent developments in the context of an ugly history and an uncertain future

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    Driven by our recent mapping of the human genome, genetics research is increasingly prominent and beginning to re-intersect with education research. We describe previous intersections of these fields, focusing specifically on the ways they were harmful. We then discuss novel features of genetics research in the current era with an emphasis on possibilities deriving from the availability of molecular genetic data and the proliferation of genome-wide association studies. We discuss both promises and potential pitfalls resulting from the convergence of molecular genetic research and education research. The floodgates of genetic data have opened. Collaboration between those in the social and hard sciences; open conversation among policy makers, educators, and researchers; and public engagement will all prove critical for enacting regulations and research designs that emphasize equity

    Genetics and Education: Recent Developments in the Context of an Ugly History and an Uncertain Future

    No full text
    Driven by our recent mapping of the human genome, genetics research is increasingly prominent and beginning to reintersect with education research. We describe previous intersections of these fields, focusing on the ways that they were harmful. We then discuss novel features of genetics research in the current era, with an emphasis on possibilities deriving from the availability of molecular genetic data and the proliferation of genome-wide association studies. We discuss both the promises and potential pitfalls resulting from the convergence of molecular genetic research and education research. The floodgates of genetic data have opened. Collaboration between those in the social and biomedical sciences; open conversation among policy makers, educators, and researchers; and public engagement will all prove critical for enacting regulations and research designs that emphasize equity

    Confronting ethical and social issues related to the genetics of musicality

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    New interdisciplinary research into genetic influences on musicality raises a number of ethical and social issues for future avenues of research and public engagement. The historical intersection of music cognition and eugenics heightens the need to vigilantly weigh potential risks and benefits of these studies and use of their outcomes. Here we bring together diverse perspectives (complex trait genetics, music cognition, musicology, bioethics, and neuroscience) to guide ethical use of this new knowledge. We discuss a framework for incorporating principles of ethically and socially responsible conduct of musicality genetics research into each stage of the research lifecycle: study design, study implementation, potential applications, and communication about the research

    Confronting ethical and social issues related to the genetics of musicality

    Get PDF
    New interdisciplinary research into genetic influences on musicality raises a number of ethical and social issues for future avenues of research and public engagement. The historical intersection of music cognition and eugenics heightens the need to vigilantly weigh the potential risks and benefits of these studies and the use of their outcomes. Here, we bring together diverse disciplinary expertise (complex trait genetics, music cognition, musicology, bioethics, developmental psychology, and neuroscience) to interpret and guide the ethical use of findings from recent and future studies. We discuss a framework for incorporating principles of ethically and socially responsible conduct of musicality genetics research into each stage of the research lifecycle: study design, study implementation, potential applications, and communication

    Genetic Fortune:Winning or Losing Education, Income, and Health

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    We develop a polygenic index for individual income and examine random differences in this index with lifetime outcomes in a sample of ~35,000 biological siblings. We find that genetic fortune for higher income causes greater socio-economic status and better health, partly via intervenable environmental pathways such as education. The positive returns to schooling remain substantial even after controlling for now observable genetic confounds. Our findings illustrate that inequalities in education, income, and health are partly due the outcomes of a genetic lottery. However, the consequences of different genetic endowments are malleable, for example via policies that target education
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