The Magnitude of Charge Effects on the Fluorescence Quenching of Peptidyl Tryptophan by Iodide

The magnitude of charge effects on the quenching of tryptophan containing peptides by Iodine is compared for those peptides containing a positvely charged tryptophan to those peptides containing a negatively or uncharged tryptophan

High Resolution mid-Infrared Imaging of SN 1987A

Using the Thermal-Region Camera and Spectrograph (T-ReCS) attached to the Gemini South 8m telescope, we have detected and resolved 10 micron emission at the position of the inner equatorial ring (ER) of supernova SN 1987A at day 6067. ``Hot spots'' similar to those found in the optical and near-IR are clearly present. The morphology of the 10 micron emission is globally similar to the morphology at other wavelengths from X-rays to radio. The observed mid-IR flux in the region of SN1987A is probably dominated by emission from dust in the ER. We have also detected the ER at 20 micron at a 4 sigma level. Assuming that thermal dust radiation is the origin of the mid-IR emission, we derive a dust temperature of 180^{+20}_{-10} K, and a dust mass of 1.- 8. 10^{-5} Mo for the ER. Our observations also show a weak detection of the central ejecta at 10 micron. We show that previous bolometric flux estimates (through day 2100) were not significantly contaminated by this newly discovered emission from the ER. If we assume that the energy input comes from radioactive decays only, our measurements together with the current theoretical models set a temperature of 90 leq T leq 100 K and a mass range of 10^{-4} - 2. 10^{-3} Mo for the dust in the ejecta. With such dust temperatures the estimated thermal emission is 9(+/-3) 10^{35} erg s^{-1} from the inner ring, and 1.5 (+/-0.5) 10^{36} erg s^{-1} from the ejecta. Finally, using SN 1987A as a template, we discuss the possible role of supernovae as major sources of dust in the Universe.Comment: aastex502, 14 pages, 4 figures; Accepted for publication in ApJ Content changed: new observations, Referee's comments and suggestion

Detection of a light echo from SN1998bu

About 500d after explosion the light curve of the Type Ia SN1998bu suddenly flattened and at the same time the spectrum changed from the typical nebular emission to a blue continuum with broad absorption and emission features reminiscent of the SN spectrum at early phases. We show that in analogy to SN1991Tbu (Schmidt et al. 1994), this can be explained by the emergence of a light echo from a foreground dust cloud. Based on a simple model we argue that the amount of dust required can consistently explain the extinction which has been estimated by completely independent methods. Because of the similar echo luminosity but much higher optical depth of the dust in SN1998bu compared with SN1991T, we expect that the echo ring size of SN1998bu grows faster than in SN1991T. HST observations have indeed confirmed this prediction.Comment: 5 pages (including 3 figures) - Accepted for pubblication in ApJ Letter

Deep Chandra and multicolor HST observations of the jets of 3C 371 and PKS 2201+044

This paper presents multiwavelength imaging and broad-band spectroscopy of the relativistic jets in the two nearby radio galaxies 3C 371 and PKS 2201+044, acquired with Chandra, HST, VLA, and Merlin. Radio polarization images are also available. The two sources stand out as "intermediate'' between FRIs and FRIIs; their cores are classified as BL Lacs, although broad and narrow optical emission lines were detected at times. The multiwavelength images show jet morphologies with the X-ray emission peaking closer to the nucleus than the longer wavelengths. The jets are resolved at all wavelengths in a direction perpendicular to the jet axis. The jets SEDs are consistent with a single spectral component from radio to X-rays, interpreted as synchrotron emission. The SEDs show a progressive softening from the inner to the outer regions of the jet, indicating that the electron break energy moves to lower energies with distance from the core. Overall, the X-ray and multiwavelength properties of the jets of 3C 371 and PKS 2201+044 appear intermediate between those of FRIs and FRIIs.Comment: Accepted for publication in ApJ; 28 pages (emulateapj5), 17 figure

The Pediatric Sepsis Biomarker Risk Model (PERSEVERE) Biomarkers Predict Clinical Deterioration and Mortality in Immunocompromised Children Evaluated for Infection

Pediatric sepsis and bacterial infection cause significant morbidity and mortality worldwide, with immunocompromised patients being at particularly high risk of rapid deterioration and death. This study evaluated if PERSEVERE, PERSEVERE-II, or the PERSEVERE biomarkers, can reliably estimate the risk of clinical deterioration and 28-day mortality among immunocompromised pediatric patients. This is a single-center prospective cohort study conducted from July 2016 through September 2017 incorporating 400 episodes of suspected bacterial infection from the inpatient units at Cincinnati Children's Hospital Medical Center, a large, tertiary care children's hospital. The primary analysis assessed clinical deterioration within 72 hours of evaluation for infection. Secondarily, we assessed 28-day mortality. Clinical deterioration was seen in 15% of subjects. Twenty-eight day mortality was 5%, but significantly higher among critically ill patients. Neither PERSEVERE nor PERSEVERE-II performed well to predict clinical deterioration or 28-day mortality, thus we derived new stratification models using the PERSEVERE biomarkers with both high sensitivity and negative predictive value. In conclusion, we evaluated previously validated biomarker risk models in a novel population of largely non-critically ill immunocompromised pediatric patients, and attempted to stratify patients based on a new outcome metric, clinical deterioration. The new highly predictive models indicate common physiologic pathways to clinical deterioration or death from bacterial infection

The Local Group Census: planetary nebulae in Sextans B

Five planetary nebulae (PNe) have been discovered in the nearby dwarf irregular galaxy. Emission line images were obtained using the Wide Field Camera of the 2.5m Isaac Newton Telescope (INT) at La Palma (Spain). The candidate PNe were identified by their point-like appearance and relatively strong [OIII] emission-line fluxes. They are located within a galactocentric distance of 2.8 arcmin, corresponding to 1.1 kpc at the distance of Sextans B. Luminosities are in the range 1800--5600Lsolar. Sextans B is one of the smallest dwarf irregular galaxies with a PN population. The number of PNe detected suggest an enhanced star formation rate between 1 and 5 Gyr ago.Comment: 7 pages, 2 figure

Extended Emission Line Gas in Radio Galaxies - PKS0349-27

PKS0349-27 is a classical FRII radio galaxy with an AGN host which has a spectacular, spiral-like structure in its extended emission line gas (EELG). We have measured the velocity field in this gas and find that it splits into 2 cloud groups separated by radial velocities which at some points approach 400 km/s Measurements of the diagnostic emission line ratios [OIII]5007/H-beta, [SII]6716+6731/H-alpha, and [NII]6583/H-alpha in these clouds show no evidence for the type of HII region emission associated with starburst activity in either velocity system. The measured emission line ratios are similar to those found in the nuclei of narrow-line radio galaxies, but the extended ionization/excitation cannot be produced by continuum emission from the active nucleus alone. We present arguments which suggest that the velocity disturbances seen in the EELG are most likely the result of a galaxy-galaxy collision or merger but cannot completely rule out the possibility that the gas has been disrupted by the passage of a radio jet.Comment: 12 pages, 3 fig pages, to appear in the Astrophys.

Spectral statistics of random geometric graphs

We use random matrix theory to study the spectrum of random geometric graphs, a fundamental model of spatial networks. Considering ensembles of random geometric graphs we look at short range correlations in the level spacings of the spectrum via the nearest neighbour and next nearest neighbour spacing distribution and long range correlations via the spectral rigidity Delta_3 statistic. These correlations in the level spacings give information about localisation of eigenvectors, level of community structure and the level of randomness within the networks. We find a parameter dependent transition between Poisson and Gaussian orthogonal ensemble statistics. That is the spectral statistics of spatial random geometric graphs fits the universality of random matrix theory found in other models such as Erdos-Renyi, Barabasi-Albert and Watts-Strogatz random graph.Comment: 19 pages, 6 figures. Substantially updated from previous versio

Critical field-exponents for secure message-passing in modular networks

We study secure message-passing in the presence of multiple adversaries in modular networks. We assume a dominant fraction of nodes in each module have the same vulnerability, i.e., the same entity spying on them. We find both analytically and via simulations that the links between the modules (interlinks) have effects analogous to a magnetic field in a spin-system in that for any amount of interlinks the system no longer undergoes a phase transition. We then define the exponents δ, which relates the order parameter (the size of the giant secure component) at the critical point to the field strength (average number of interlinks per node), and γ, which describes the susceptibility near criticality. These are found to be δ = 2 and γ = 1 (with the scaling of the order parameter near the critical point given by β = 1). When two or more vulnerabilities are equally present in a module we find δ = 1 and γ = 0 (with β ≥ 2). Apart from defining a previously unidentified universality class, these exponents show that increasing connections between modules is more beneficial for security than increasing connections within modules. We also measure the correlation critical exponent ν, and the upper critical dimension d c, finding that as for ordinary percolation, suggesting that for secure message-passing d c = 6. These results provide an interesting analogy between secure message-passing in modular networks and the physics of magnetic spin-systems

Spectroscopy of planetary nebulae in M33

Spectroscopic observations of 48 emission-line objects of M33 have been obtained with the multi-object, wide field, fibre spectrograph AF2/WYFFOS at the 4.2m WHT telescope (La Palma, Spain). Line intensities and logarithmic extinction, cbeta, are presented for 42 objects. Their location in the Sabbadin & D'Odorico diagnostic diagram (Halpha/[SII] vs Hlapha/[NII]) suggests that >70% of the candidates are Planetary Nebulae (PNe). Chemical abundances and nebular physical parameters have been derived for the three of the six PNe where the 4363A [OIII] emission line was measurable. These are disc PNe, located within a galactocentric distance of 4.1 kpc, and, to date, they are the farthest PNe with a direct chemical abundance determination. No discrepancy in the Helium, Oxygen and Argon abundances has been found in comparison with corresponding abundances of PNe in our Galaxy. Only a lower limit to the sulphur abundance has been obtained since we could not detect any [SIII] line. N/H appears to be lower than the Galactic value; some possible explanations for this under-abundance are discussed.Comment: 18 pages, 1 JPEG figure and 3 Postscript figures, Accepted for publication in A&