Activity of thyme oil ("Oleum Thymi") against multidrug-resistant "Acinetobacter baumannii" and "Pseudomonas aeruginosa"

Almost as soon as antibiotics were introduced to treat infectious diseases, it could be observed that bacteria were able to develop resistance against them. Currently, multidrug-resistant strains are being isolated mainly in the hospital environment. These are primarily non-fermenting Gram-negative bacilli, which exhibit both natural and acquired resistance to multiple antibiotics and disinfectants rendering them difficult to eradicate. The development of new, effective and safe substances that prevent troublesome infections is greatly needed to provide alternative therapeutic options for patients. There is increasing interest in drugs of natural origin, including essential oils. It is of particular interest that, although active against many bacterial strains, they do not contribute to antibacterial resistance against their components. The aim of our study was to evaluate the in vitro antibacterial activity of thyme oil against multidrug-resistant strains of A. baumannii and P. aeruginosa using the disc diffusion and macrodilution methods. The strains were isolated from patients hospitalized in the years 2013-2014. The in vitro antibacterial activity of thyme oil was assessed by the disc diffusion method and the inhibition zones for the oil at different concentrations, produced against A. baumannii, ranged from 7 to 44 mm. Low level of activity of thyme oil was observed against P. aeruginosa strains. The results of serial dilution tests confirmed the high activity of thyme oil against A. baumannii isolates, expressed as MIC values ranging from 0.25 to 2 μL/mL. These results suggest the need for further studies of antibacterial activity of essential oils, especially against multidrug-resistant bacterial isolates

A triterpene saponin from "Lysimachia thyrsiflora L."

A triterpene saponoside (LTS-4) isolated from the underground parts of Lysimachia thyrsiflora L. was defined as 3-O-{β-D-xylopyranosyl-(1→2)-β-D-glucopyranosyl-(1→4)-[β-D-glucopyranosyl-(1→2)]-α- L-arabinopyranosyl}-cyclamiretin A. Structure assignment was performed on the basis of spectroscopic data including homo- and heteronuclear 1D and 2D NMR (COSY, TOCSY, NOESY, HETCOR, HMBC and DEPT) and FAB-MS studies. The compound was tested in vitro for antimicrobial and cytotoxic activity

Clinical competencies of nurses and forms of postgraduate education

Introduction Over the last few years, the health care system has been transforming. The qualifications of medical staff are systematically improving due to the increasing pressure to raise the level of competence in line with the development of medicine and the expectations of healthcare recipients. Aim The aim of the study is the comparison of the clinical competence of the nurses whilst taking into the account the forms of postgraduate education. Material and research methods The study included 120 nurses aged 24-53 years, working in paediatric wards in Antoni Gębala University Hospital for Children in Lublin. The research tool was a questionnaire Belimage which contains 38 questions covering five areas: demographics, competence, nursing care, teamwork and care environment. Results The research demonstrates that the professional competence level of the respondents was the most significantly influenced by: practical experience and own reflections (85.00%), introduction in the current workplace (52.50%), sharing competence and experience with colleagues-nurses (tutorial guidance, working meetings, conversations) (51.67%). In the surveyed group, 100% of the respondents claimed that it was necessary to invest in various fields in order to optimize the level of nursing competence. The nurses who completed a specialization (43.48%) and higher education (79.17%) also evaluated the quality of care as excellent. Instrumental and technical competencies (4.50), as well as social and communication skills (4.20) are important for the nurses with Master’s degree. Conclusions It has been proven that practical experience and own perspectives have the biggest influence on the respondents’ professional competence level. Investing in various forms of postgraduate education and training, such as specialist courses and training, and university education, will optimize the level of nursing proficiency. Education, work experience and the time elapsed since graduation do not affect the assessment of the level of respondents’ competence. The survey participants with higher education, specialization and certificates of completed training, felt slightly more often that the quality of patient care on the ward is excellent

Analiza przyczyn biegunki ostrej u niemowląt jako wyznacznik profilaktyki pierwotnej i wtórnej = Analysis of the causes of acute diarrhea in infants as a marker of primary and secondary prevention

Stadnicka Sabina Katarzyna, Brodowicz-Król Magdalena, Trojanowska Alina, Zarzycka Danuta. Analiza przyczyn biegunki ostrej u niemowląt jako wyznacznik profilaktyki pierwotnej i wtórnej = Analysis of the causes of acute diarrhea in infants as a marker of primary and secondary prevention. Journal of Education, Health and Sport. 2016;6(7):91-102. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.57157http://ojs.ukw.edu.pl/index.php/johs/article/view/3670   The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 755 (23.12.2015).755 Journal of Education, Health and Sport eISSN 2391-8306 7© The Author (s) 2016;This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, PolandOpen Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium,provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License(http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercialuse, distribution and reproduction in any medium, provided the work is properly cited.The authors declare that there is no conflict of interests regarding the publication of this paper.Received: 25.05.2016. Revised 25.06.2016. Accepted: 28.06.2016. Analiza przyczyn biegunki ostrej u niemowląt jako wyznacznik profilaktyki pierwotnej i wtórnejAnalysis of the causes of acute diarrhea in infants as a marker of primary and secondary prevention Sabina Katarzyna Stadnicka, Magdalena Brodowicz-Król, Alina Trojanowska, Danuta Zarzycka Katedra i Zakład Pielęgniarstwa Pediatrycznego, Wydział Nauk o Zdrowiu, Uniwersytetu Medycznego w Lublinie   Sabina Katarzyna Stadnicka, mgr położnictwa, doktorantka,  Katedra i Zakład Pielęgniarstwa Pediatrycznego, Wydział Nauk o Zdrowiu, Uniwersytetu Medycznego w Lublinie;Magdalena Brodowicz-Król, mgr pielęgniarstwa, mgr pedagogiki, asystent Katedra i Zakład Pielęgniarstwa Pediatrycznego, Wydział Nauk o Zdrowiu, Uniwersytetu Medycznego w Lublinie Alina Trojanowska, dr n. med., adiunkt, Katedra i Zakład Pielęgniarstwa Pediatrycznego, Wydział Nauk o Zdrowiu, Uniwersytetu Medycznego w LublinieDanuta Zarzycka, dr hab. n. o zdrowiu, adiunkt,  Katedra i Zakład Pielęgniarstwa Pediatrycznego Wydział Nauk o Zdrowiu, Uniwersytetu Medycznego w Lublinie StreszczenieWprowadzenie: W populacji dziecięcej jednym z najczęstszych zaburzeń rytmu wypróżniania są biegunki. Na ostrą biegunkę choruje praktycznie każde dziecko poniżej 3. roku życia.Cel: Celem pracy jest przedstawienie przyczyn występowania i zasad postępowania w biegunce ostrej u niemowląt ze zwróceniem szczególnej uwagi na profilaktykę i postępowanie przedszpitalne.Metoda: Przegląd tematyczny literatury przedmiotu obejmujący okres od 2006 do 2016 roku.Wyniki: Za większość ostrych nieżytów żołądkowo-jelitowych odpowiedzialne są zakażenia rota wirusowe. Infekcje mogą mieć zróżnicowany przebieg. Zakażenie o łagodnym przebiegu, charakteryzuje się wodnistymi stolcami, współwystępowaniem wymiotów oraz nieżytu górnych dróg oddechowych. Przebieg ciężki biegunki często powoduje powstanie objawów znacznego odwodnienia i zaburzenia gospodarki wodno-elektrolitowej i kwasowo-zasadowej. Pojawiająca się krew w stolcu świadczy o współistniejącym zakażeniu bakteryjnym. Podstawowym postępowaniem w trakcie biegunek jest wypełnienie łożyska naczyniowego za pomocą doustnych płynów nawadniających. W niektórych przypadkach konieczne jest leczenie w warunkach szpitalnych.Podsumowanie: Ze względu na najczęstszą etiologię biegunki u dzieci, czyli zakażenia wirusowe i łatwość przenoszenia zakażeń, profilaktykę opiera się na zachowaniu szczególnej dbałości o higienę (w tym przede wszystkim częste mycie rąk). Słowa kluczowe: biegunka ostra, niemowlęta, rotawirusy, profilaktyka. Abstract Introduction: in the pediatric population one of the most common irregular bowel movements are diarrhea. Acute diarrhoea have virtually every child below 3. year of life. Objective: the aim of the work is the presentation of the causes of and the rules of conduct in acute diarrhea in infants with special attention to the prevention and treatment przedszpitalne. Method: a review of thematic literature covering the period from 2006 to 2016. Results: the most acute gastrointestinal infection are responsible nieżytów rota virus. Infections can be differentiated. Mild infection, characterized by wodnistymi stools, interaction of vomiting and respiratory tract mucus secretion. The course of severe diarrhea often causes signs of significant dehydration and disorders of water and electrolyte and acid-base.That appears to be blood in the stool indicates a particular bacterial infection. The primary consideration in the course of diarrhea is to fill the vascular bed using oral irrigation fluids. In some cases it is necessary to treatment in a hospital. Summary: due to the most common etiology of diarrhea in children, that is, viral infections and ease of cross infection, prevention is based on maintaining special attention to hygiene (including especially frequent hand washing). Key words: acute diarrhea, infants, Rotarix, prevention

Plan De Intervención Sobre La Puntualidad escolar Para Fortalecer La Identidad Cultural en Los Alumnos De La Institución Educativa N°16213. Tomocho, Bagua Grande, Utcubamba.

La investigación titulada: “Plan de intervención sobre la puntualidad escolar para fortalecer la identidad cultural en los alumnos de la institución educativa N°16213. Tomocho, Bagua Grande, Utcubamba”, tiene como objetivo: “Determinarla influencia del plan de intervención sobre la puntualidad escolar se fortalece la identidad cultural en los alumnos de la institución educativa N° 16213. Tomocho,Bagua Grande, Utcubamba” El estudio se abordó en el marco de una investigación cuantitativa a través del desarrollo del tipo de investigación aplicativa–explicativa, se aplicó un plan de intervención sobre la puntualidad escolar y se explica a través de las teorías científicas, a través de un diseño pre experimental con un solo grupo, en una muestra de 26 estudiantes de la institución educativa en mención. La variable identidad cultural se ejecutó con las dimensiones: gastronomía, música y danzas tradicionales y artesanías; del mismo modo la variable plan de intervención sobre la puntualidad escolar se ejecutó con el desarrollo de las dimensiones: aumento de eficacia, incremento de confianza, adquisición de respeto y conquista del empleo En los resultados alcanzados se observa que de los 26 alumnos entrevistados antes de aplicar el programa en las tres dimensiones se ubicaron en el nivel bajo gastronomía 53.8%, Música y danza 46.2% y artesanías 50%.Mientras que después de aplicar el programa alcanzaron un nivel muy bueno gastronomía 46.2%, Música y danzas 38.5% y artesanía 23.1%. Demostrando de esa manera la eficacia del plan de intervención sobre puntualidad escolar

New insight of parenteral nutrition in children – short review

Abstract Admission. Parenteral nutrition (parenteral) is the supply of all essential nutrients - proteins, carbohydrates, fats, electrolytes, vitamins, trace elements and water intravenously. Parenteral nutrition is a generally available method of nutritional treatment used when the supply of food through the gastrointestinal tract is impossible, insufficient or contraindicated. Complete parenteral nutrition should be replaced as soon as possible with feeding to the gastrointestinal tract. Chronic diseases in children are often complicated by serious nutritional deficiencies

Mechanical thrombectomy in acute stroke – Five years of experience in Poland

Objectives Mechanical thrombectomy (MT) is not reimbursed by the Polish public health system. We present a description of 5 years of experience with MT in acute stroke in Comprehensive Stroke Centers (CSCs) in Poland. Methods and results We retrospectively analyzed the results of a structured questionnaire from 23 out of 25 identified CSCs and 22 data sets that include 61 clinical, radiological and outcome measures. Results Most of the CSCs (74%) were founded at University Hospitals and most (65.2%) work round the clock. In 78.3% of them, the working teams are composed of neurologists and neuro-radiologists. All CSCs perform CT and angio-CT before MT. In total 586 patients were subjected to MT and data from 531 of them were analyzed. Mean time laps from stroke onset to groin puncture was 250±99min. 90.3% of the studied patients had MT within 6h from stroke onset; 59.3% of them were treated with IV rt-PA prior to MT; 15.1% had IA rt-PA during MT and 4.7% – emergent stenting of a large vessel. M1 of MCA was occluded in 47.8% of cases. The Solitaire device was used in 53% of cases. Successful recanalization (TICI2b–TICI3) was achieved in 64.6% of cases and 53.4% of patients did not experience hemorrhagic transformation. Clinical improvement on discharge was noticed in 53.7% of cases, futile recanalization – in 30.7%, mRS of 0–2 – in 31.4% and mRS of 6 in 22% of cases. Conclusion Our results can help harmonize standards for MT in Poland according to international guidelines