220 research outputs found
Constitutional Change in a Long-Depressed Community: A Case Study of Duluth, Minnesota
Duluth, a boom and bust city with a marginal economy, has a unique position outside the mainstream of American life that adds a different dimension lo the understanding of community politics. Settlement patterns have contributed to the development of separate business and labor subcommunities that are substantially alienated from and hostile to one another and have rarely been able to cooperate in any civic endeavor. Operating within the framework of a political system caricaturing that of Minnesota as a whole, the two subcommunities reversed the pattern of local concern found in other cities; labor became the progressive force in local matters while business played a highly conservative role. Since World War II, the decline of the city\u27s established economic base hos been completed. At the same time, the Democratic-Farmer- Labor Party has emerged as the dominant political party locally. Its leaders, in alliance with organized labor, have tried to do something about Duluth\u27s predicament. In J 956, they secured a major change in the city\u27s form of government that was designed to open the door to progress an other fronts. Ta do so, they forged an alliance with the business community that, at least temporarily, transcended the city\u27s normal cleavage. While the constitutional change was of little immediate importance, the effect of the alliance was ta convince community leaders on both sides that cooperation for civic improvement was possible, thus opening the door lo a series of government-aided developments that may hove for-reaching consequences for Duluth\u27s economic and social well-being
Not Written in Stone
Using long-ignored constitutions of various Jewish organizations, this unique book uncovers the political history of Canadian Jewry since its beginning during the 1700s. Building on the premise that Jews, since time immemorial, have written down their values and ideologies, this study effectively demonstrates how these writings record the principles and values that motivated a community
The Impact of Advocacy Organizations on Low-Income Housing Policy in U.S. Cities
Financial support for affordable housing competes with many other municipal priorities. This work seeks to explain the variation in support for affordable housing among U.S. cities with populations of 100,000 or more. Using multivariate statistical analysis, this research investigates political explanations for the level of city expenditures on housing and community with a particular interest in the influence of housing advocacy organizations (AOs). Data for the model were gathered from secondary sources, including the U.S. Census and the National Center for Charitable Statistics. Among other results, the analysis indicates that, on average, the political maturity of AOs has a statistically significant, positive effect on local housing and community development expenditures
Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence:Supporting the next generation of autophagy researchers and fostering international collaborations
Recently, NIH has funded a center for autophagy research named the Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence, located at the University of New Mexico Health Science Center (UNM HSC), with aspirations to promote autophagy research locally, nationally, and internationally. The center has 3 major missions: (i) to support junior faculty in their endeavors to develop investigations in this area and obtain independent funding; (ii) to develop and provide technological platforms to advance autophagy research with emphasis on cellular approaches for high quality reproducible research; and (iii) to foster international collaborations through the formation of an International Council of Affiliate Members and through hosting national and international workshops and symposia. Scientifically, the AIM center is focused on autophagy and its intersections with other processes, with emphasis on both fundamental discoveries and applied translational research.</p
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Model International Mobility Convention
While people are as mobile as they ever were in our globalized world, the movement of people across borders lacks global regulation. This leaves many refugees in protracted displacement and many migrants unprotected in irregular and dire situations. Meanwhile, some states have become concerned that their borders have become irrelevant. International mobilityâthe movement of individuals across borders for any length of time as visitors, students, tourists, labor migrants, entrepreneurs, long-term residents, asylum seekers, or refugeesâhas no common definition or legal framework. To address this key gap in international law, and the growing gaps in protection and responsibility that are leaving people vulnerable, the "Model International Mobility Convention" proposes a framework for mobility with the goals of reaffirming the existing rights afforded to mobile people (and the corresponding rights and responsibilities of states) as well as expanding those basic rights where warranted. In 213 articles divided over eight chapters, the Convention establishes both the minimum rights afforded to all people who cross state borders as visitors, and the special rights afforded to tourists, students, migrant workers, investors and residents, forced migrants, refugees, migrant victims of trafficking and migrants caught in countries in crisis. Some of these categories are covered by existing international legal regimes. However, in this Convention these groups are for the first time brought together under a single framework. An essential feature of the Convention is that it is cumulative. This means, for the most part, that the chapters build on and add rights to the set of rights afforded to categories of migrants covered by earlier chapters. The Convention contains not only provisions that afford rights to migrants and, to a lesser extent, States (such as the right to decide who can enter and remain in their territory). It also articulates the responsibilities of migrants vis-Ă -vis States and the rights and responsibilities of different institutions that do not directly respond to a right held by migrants
Beth Levine in memoriam
Beth Levine was born on 7 April 1960 in Newark, New Jersey. She went to college at Brown University where she received an A.B. Magna Cum Laude, and she attended medical school at Cornell University Medical College, receiving her MD in 1986. She completed her internship and residency in Internal Medicine at Mount Sinai Hospital in New York, and her fellowship in Infectious Diseases at The Johns Hopkins Hospital. Most recently, Beth was a Professor of Internal Medicine and Microbiology, Director of the Center for Autophagy Research, and holder of the Charles Sprague Distinguished Chair in Biomedical Science at the University of Texas Southwestern Medical Center in Dallas. Beth died on 15 June 2020 from cancer. Beth is survived by her husband, Milton Packer, and their two children, Rachel (26 years old) and Ben (25 years old).
Dr. Levine was as an international leader in the field of autophagy research. Her laboratory identified the mammalian autophagy gene BECN1/beclin 1; identified conserved mechanisms underlying the regulation of autophagy (e.g. BCL2-BECN1 complex formation, insulin-like signaling, EGFR, ERBB2/HER2 and AKT1-mediated BECN1 phosphosphorylation); and provided the first evidence that autophagy genes are important in antiviral host defense, tumor suppression, lifespan extension, apoptotic corpse clearance, metazoan development, Na,K-ATPase-regulated cell death, and the beneficial metabolic effects of exercise. She developed a potent autophagy-inducing cell permeable peptide, Tat-beclin 1, which has potential therapeutic applications in a range of diseases. She was a founding Associate Editor of the journal Autophagy and an editorial board member of Cell and Cell Host & Microbe. She has received numerous awards/honors in recognition of her scientific achievement, including: The American Cancer Society Junior Faculty Research Award (1994); election into the American Society of Clinical Investigation (2000); the Ellison Medical Foundation Senior Scholars Award in Global Infectious Diseases (2004); elected member, American Association of Physicians (2005); appointment as a Howard Hughes Medical Institute Investigator (2008); Edith and Peter OâDonnell Award in Medicine (2008); elected fellow, American Association for the Advancement of Science (2012); election into the National Academy of Sciences (2013); election into the Academy of Medicine, Engineering and Science of Texas (2013); the ASCI Stanley J. Korsmeyer Award (2014); Phyllis T. Bodel Women in Medicine Award, Yale University School of Medicine (2018); recipient, Barcroft Medal, Queenâs University Belfast (2018).Fil: An, Zhenyi. No especifĂca;Fil: Ballabi, Andrea. No especifĂca;Fil: Bennett, Lynda. No especifĂca;Fil: Boya, Patricia. No especifĂca;Fil: Cecconi, Francesco. No especifĂca;Fil: Chiang, Wei Chung. No especifĂca;Fil: Codogno, Patrice. No especifĂca;Fil: Colombo, Maria Isabel. No especifĂca;Fil: Cuervo, Ana Maria. No especifĂca;Fil: Debnath, Jayanta. No especifĂca;Fil: Deretic, Vojo. No especifĂca;Fil: Dikic, Ivan. No especifĂca;Fil: Dionne, Keith. No especifĂca;Fil: Dong, Xiaonan. No especifĂca;Fil: Elazar, Zvulun. No especifĂca;Fil: Galluzzi, Lorenzo. No especifĂca;Fil: Gentile, Frank. No especifĂca;Fil: Griffin, Diane E.. No especifĂca;Fil: Hansen, Malene. No especifĂca;Fil: Hardwick, J. Marie. No especifĂca;Fil: He, Congcong. No especifĂca;Fil: Huang, Shu Yi. No especifĂca;Fil: Hurley, James. No especifĂca;Fil: Jackson, William T.. No especifĂca;Fil: Jozefiak, Cindy. No especifĂca;Fil: Kitsis, Richard N.. No especifĂca;Fil: Klionsky, Daniel J.. No especifĂca;Fil: Kroemer, Guido. No especifĂca;Fil: Meijer, Alfred J.. No especifĂca;Fil: MelĂ©ndez, Alicia. No especifĂca;Fil: Melino, Gerry. No especifĂca;Fil: Mizushima, Noboru. No especifĂca;Fil: Murphy, Leon O.. No especifĂca;Fil: Nixon, Ralph. No especifĂca;Fil: Orvedahl, Anthony. No especifĂca;Fil: Pattingre, Sophie. No especifĂca;Fil: Piacentini, Mauro. No especifĂca;Fil: Reggiori, Fulvio. No especifĂca;Fil: Ross, Theodora. No especifĂca;Fil: Rubinsztein, David C.. No especifĂca;Fil: Ryan, Kevin. No especifĂca;Fil: Sadoshima, Junichi. No especifĂca;Fil: Schreiber, Stuart L.. No especifĂca;Fil: Scott, Frederick. No especifĂca;Fil: Sebti, Salwa. No especifĂca;Fil: Shiloh, Michael. No especifĂca;Fil: Shoji, Sanae. No especifĂca;Fil: Simonsen, Anne. No especifĂca;Fil: Smith, Haley. No especifĂca;Fil: Sumpter, Kathryn M.. No especifĂca;Fil: Thompson, Craig B.. No especifĂca;Fil: Thorburn, Andrew. No especifĂca;Fil: Thumm, Michael. No especifĂca;Fil: Tooze, Sharon. No especifĂca;Fil: Vaccaro, Maria Ines. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Oficina de CoordinaciĂłn Administrativa Houssay. Instituto de BioquĂmica y Medicina Molecular. Universidad de Buenos Aires. Facultad Medicina. Instituto de BioquĂmica y Medicina Molecular; ArgentinaFil: Virgin, Herbert W.. No especifĂca;Fil: Wang, Fei. No especifĂca;Fil: White, Eileen. No especifĂca;Fil: Xavier, Ramnik J.. No especifĂca;Fil: Yoshimori, Tamotsu. No especifĂca;Fil: Yuan, Junying. No especifĂca;Fil: Yue, Zhenyu. No especifĂca;Fil: Zhong, Qing. No especifĂca
História da genética no Brasil: um olhar a partir do Museu da Genética da Universidade Federal do Rio Grande do Sul
A ação externa dos governos subnacionais no Brasil: os casos do Rio Grande do Sul e de Porto Alegre. Um estudo comparativo de dois tipos de atores mistos
Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence: supporting the next generation of autophagy researchers and fostering international collaborations
Recently, NIH has funded a center for autophagy research named the Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence, located at the University of New Mexico Health Science Center (UNM HSC), with aspirations to promote autophagy research locally, nationally, and internationally. The center has 3 major missions: (i) to support junior faculty in their endeavors to develop investigations in this area and obtain independent funding; (ii) to develop and provide technological platforms to advance autophagy research with emphasis on cellular approaches for high quality reproducible research; and (iii) to foster international collaborations through the formation of an International Council of Affiliate Members and through hosting national and international workshops and symposia. Scientifically, the AIM center is focused on autophagy and its intersections with other processes, with emphasis on both fundamental discoveries and applied translational research
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