472 research outputs found
Evolution in range expansions with competition at rough boundaries.
When a biological population expands into new territory, genetic drift develops an enormous influence on evolution at the propagating front. In such range expansion processes, fluctuations in allele frequencies occur through stochastic spatial wandering of both genetic lineages and the boundaries between genetically segregated sectors. Laboratory experiments on microbial range expansions have shown that this stochastic wandering, transverse to the front, is superdiffusive due to the front's growing roughness, implying much faster loss of genetic diversity than predicted by simple flat front diffusive models. We study the evolutionary consequences of this superdiffusive wandering using two complementary numerical models of range expansions: the stepping stone model, and a new interpretation of the model of directed paths in random media, in the context of a roughening population front. Through these approaches we compute statistics for the times since common ancestry for pairs of individuals with a given spatial separation at the front, and we explore how environmental heterogeneities can locally suppress these superdiffusive fluctuations
The Pariah Principle
The Supreme Court\u27s recent decision in Romer v. Evans\u27 has caused both joy and consternation. Among legal scholars, however, it has mostly engendered puzzlement. The Court explicitly avoided the most doctrinally plausible grounds for invalidating Colorado\u27s ban on anti-discrimination protections for homosexuals. Instead it purported to strike down the state constitutional amendment under minimal scrutiny or rational basis review. The word on the street-or, in the case of lawyers and law professors, the word on the internet-is that Romer cannot mean what it says, but instead must be a way-station to declaring homosexuality a quasi-suspect classification like gender or illegitimacy. The speculation is that the Court will eventually use Romer to strike down prohibitions on same-sex marriages and other restrictions on gay rights. We believe this line of reasoning gives the Romer majority too little credit for intellectual honesty, if perhaps too much credit for progressive impulses.2 In this essay, we suggest that the decision in Romer means no more and no less than what it says (or at least tries to say): that Colorado\u27s Amendment 2 is invalid regardless of the level of judicial scrutiny. Moreover, we contend that this conclusion does not significantly expand current law but is instead perfectly justifiable under existing precedent. The decision also does not necessarily threaten most other restrictions on homosexuals, including bans on same-sex marriage
The Pariah Principle.
The Supreme Court\u27s recent decision in Romer v. Evans\u27 has caused both joy and consternation. Among legal scholars, however, it has mostly engendered puzzlement. The Court explicitly avoided the most doctrinally plausible grounds for invalidating Colorado\u27s ban on anti-discrimination protections for homosexuals. Instead it purported to strike down the state constitutional amendment under minimal scrutiny or rational basis review. The word on the street-or, in the case of lawyers and law professors, the word on the internet-is that Romer cannot mean what it says, but instead must be a way-station to declaring homosexuality a quasi-suspect classification like gender or illegitimacy. The speculation is that the Court will eventually use Romer to strike down prohibitions on same-sex marriages and other restrictions on gay rights. We believe this line of reasoning gives the Romer majority too little credit for intellectual honesty, if perhaps too much credit for progressive impulses.2 In this essay, we suggest that the decision in Romer means no more and no less than what it says (or at least tries to say): that Colorado\u27s Amendment 2 is invalid regardless of the level of judicial scrutiny. Moreover, we contend that this conclusion does not significantly expand current law but is instead perfectly justifiable under existing precedent. The decision also does not necessarily threaten most other restrictions on homosexuals, including bans on same-sex marriage
The National Coastal Zone Management Act of 1972
This Article will focus on those innovative sections of the Coastal Zone Management Act which provide for this expanded exercise of state-based review and regulation
Quantification of Type VI secretion system activity in macrophages infected with Burkholderia cenocepacia
More Tips: What If a Cooperative Extension Professional Must Work with Native American Institutional Review Boards?
This article focuses on working with tribal IRBs to conduct research or evaluations of projects on tribal lands. It is a follow up to a series of four recent articles designed to help Extension Professionals navigate the university IRB process. The authors use their experience with a community assessment project conducted in one small, remote community located on the Navajo Nation to illustrate some of the issues and tips for success
More Tips: Communicating with Institutional Review Boards Over the Course of Your Project
This article focuses on the continuing review process required by Institutional Review Boards. It is a follow-up to a series of recent articles designed to help Extension Professionals navigate the university IRB process. The authors present general guidelines for the continuing review process and offer some issues and tips for success
Observations of Binary Stars with the Differential Speckle Survey Instrument. VII. Measures from 2010 September to 2012 February at the WIYN Telescope
We report on speckle observations of binary stars carried out at the WIYN
Telescope over the period from September 2010 through February 2012, providing
relative astrometry for 2521 observations of 883 objects, 856 of which are
double stars and 27 of which are triples. The separations measured span a range
of 0.01 to 1.75 arc seconds. Wavelengths of 562 nm, 692 nm, and 880 nm were
used, and differential photometry at one or more of these wavelengths is
presented in most cases. Sixty-six components were resolved for the first time.
We also estimate detection limits at 0.2 and 1.0 arc seconds for high-quality
observations in cases where no companion was seen, a total of 176 additional
objects. Detection limits vary based on observing conditions and
signal-to-noise ratio, but are approximately 4 magnitudes at 0.2 arc seconds
and 6 magnitudes at 1.0 arc seconds on average. Analyzing the measurement
precision of the data set, we find that the individual separations obtained
have linear measurement uncertainties of approximately 2 mas, and photometry is
uncertain to approximately 0.1 magnitudes in general. This work provides
fundamental, well-calibrated data for future orbit and mass determinations, and
we present three first orbits and total mass estimates of nearby K-dwarf
systems as examples of this potential
Using machine learning techniques to develop forecasting algorithms for postoperative complications: Protocol for a retrospective study
Time in Nature Associated with Decreased Fatigue in UK Truck Drivers
Funding: The data presented in this paper were collected as part of the ‘Structured Health Interven- tion For Truckers (SHIFT)’ randomised controlled trial. This research was funded by the National Institute for Health Research (NIHR) Public Health Research Programme (reference: NIHR PHR 15/190/42). Funding Acquisition, S.A.C., J.A.K., V.V-M. The views expressed are those of the authors and not necessarily those of the NHS, the NIHR or the Department of Health and Social Care. Acknowledgments: SAC: JAK, AS and NJP are supported by the NIHR Leicester Biomedical Re- search Centre—Lifestyle theme. AG has received funding for their PhD Studentship from the Colt Foundation (reference: JD/618).Peer reviewedPublisher PD
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