6,249 research outputs found

    Women’s Understanding of the Effects of Obesity on Pregnancy

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    Obesity is a serious issue and is becoming a significant problem around the world. Obesity in general causes and complicates many health problems. As obesity increases in the population at large, the incidence of obesity in pregnancy continues to increase. Obesity during pregnancy has been linked in numerous studies to multiple complications, and the issues and risks have been clearly established. Also becoming pregnant or having multiple pregnancies increases the likelihood of developing obesity. Obese women of childbearing age many times do not even know these risks exist. There is a need to educate these women before they become pregnant, and there is a need to educate all women because they may be faced with these problems in the future. This study researched women’s understanding of the effects of obesity on pregnancy. The eight participants were college students chosen from a female dorm on a Christian university campus. A pretest, educational intervention, and posttest study design was implemented. The posttest scores were found to be significantly higher than the pretest scores indicating that learning took place during the intervention. This finding demonstrates the need for more education for women in general regarding these risks

    A Review and Clarification of the Terms “holistic,” “configural,” and “relational” in the Face Perception Literature

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    It is widely agreed that the human face is processed differently from other objects. However there is a lack of consensus on what is meant by a wide array of terms used to describe this “special” face processing (e.g., holistic and configural) and the perceptually relevant information within a face (e.g., relational properties and configuration). This paper will review existing models of holistic/configural processing, discuss how they differ from one another conceptually, and review the wide variety of measures used to tap into these concepts. In general we favor a model where holistic processing of a face includes some or all of the interrelations between features and has separate coding for features. However, some aspects of the model remain unclear. We propose the use of moving faces as a way of clarifying what types of information are included in the holistic representation of a face

    Aboriginal Men’s Business: A Literature Review of Factors Affecting Aboriginal Men Accessing Sexual Health Services

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    Introduction: Aboriginal men are relatively young, with a median age of 22 years, nearly half that of their non-Aboriginal counterparts. Aboriginal men also have the highest mortality rates and have the lowest life expectancy. Sexually Transmissible Infection (STI) rates are extremely overrepresented in lower socio-economic groups, including minority populations. STI rates among Aboriginal communities are significantly higher when compared to the non-Aboriginal population. Aims: In the context of multiple factors impinging on the sexual health of Aboriginal men, we sought to conduct a comprehensive review of the literature for the purpose of developing a framework through which needs and actions to improve sexual health could be identified and understood. Methods: A targeted, comprehensive search strategy was developed using keywords and synonyms related to the aims of the project. The search included scholarly peer reviewed academic literature available and grey literature from the Wollongong Hospital and the NSW Health library. The search was made more efficient by entering search terms into the Deakin University EBSCOhost search engine, and Google Scholar was searched separately. Grey literature searching was conducted with Clinical Information Access Portal (CIAP), Informit and the Commonwealth Scientific and Industrial Research Organisation (CSIRO). Results: The search produced a total number of 385 papers from peer reviewed publications and grey literature. A total of 95 duplicates were removed, leaving 290 papers. After incorporating the screening process, exclusion and inclusion criteria, the total number of articles selected for review was 31 articles. Discussion: The thematic analysis identified that cultural considerations of Aboriginal ‘Men’s business’ involving traditional lifestyle, cultural practices and the impact of colonisation were only briefly covered in the included studies. The findings of the literature review indicated that Aboriginal men’s health is deeply influenced by their socio-economic status and cultural wellbeing. This review provided limited findings relating to service provision support for Aboriginal men. Conclusion: Overall, this review presented several concerning factors and evidence of the difficulties for Aboriginal and Torres Strait Islander men accessing sexual health services. Literature identified the long-standing health statistics and deterioration of health and social and emotional wellbeing for Aboriginal and Torres Strait Islander men. While both mainstream health and non-government services are offering limited provision of culturally safe and appropriate healthcare pathways

    Biochemical Properties of a Decoy Oligodeoxynucleotide Inhibitor of STAT3 Transcription Factor.

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    Cyclic STAT3 decoy (CS3D) is a second-generation, double-stranded oligodeoxynucleotide (ODN) that mimics a genomic response element for signal transducer and activator of transcription 3 (STAT3), an oncogenic transcription factor. CS3D competitively inhibits STAT3 binding to target gene promoters, resulting in decreased expression of proteins that promote cellular proliferation and survival. Previous studies have demonstrated antitumor activity of CS3D in preclinical models of solid tumors. However, prior to entering human clinical trials, the efficiency of generating the CS3D molecule and its stability in biological fluids should be determined. CS3D is synthesized as a single-stranded ODN and must have its free ends ligated to generate the final cyclic form. In this study, we report a ligation efficiency of nearly 95 percent. The ligated CS3D demonstrated a half-life of 7.9 h in human serum, indicating adequate stability for intravenous delivery. These results provide requisite biochemical characterization of CS3D that will inform upcoming clinical trials

    Single-object Imaging and Spectroscopy to Enhance Dark Energy Science from LSST

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    Single-object imaging and spectroscopy on telescopes with apertures ranging from ~4 m to 40 m have the potential to greatly enhance the cosmological constraints that can be obtained from LSST. Two major cosmological probes will benefit greatly from LSST follow-up: accurate spectrophotometry for nearby and distant Type Ia supernovae will expand the cosmological distance lever arm by unlocking the constraining power of high-z supernovae; and cosmology with time delays of strongly-lensed supernovae and quasars will require additional high-cadence imaging to supplement LSST, adaptive optics imaging or spectroscopy for accurate lens and source positions, and IFU or slit spectroscopy to measure detailed properties of lens systems. We highlight the scientific impact of these two science drivers, and discuss how additional resources will benefit them. For both science cases, LSST will deliver a large sample of objects over both the wide and deep fields in the LSST survey, but additional data to characterize both individual systems and overall systematics will be key to ensuring robust cosmological inference to high redshifts. Community access to large amounts of natural-seeing imaging on ~2-4 m telescopes, adaptive optics imaging and spectroscopy on 8-40 m telescopes, and high-throughput single-target spectroscopy on 4-40 m telescopes will be necessary for LSST time domain cosmology to reach its full potential. In two companion white papers we present the additional gains for LSST cosmology that will come from deep and from wide-field multi-object spectroscopy.Comment: Submitted to the call for Astro2020 science white paper

    A Fresh Catch of Massive Binaries in the Cygnus OB2 Association

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    Massive binary stars may constitute a substantial fraction of progenitors to supernovae and gamma-ray bursts, and the distribution of their orbital characteristics holds clues to the formation process of massive stars. As a contribution to securing statistics on OB-type binaries, we report the discovery and orbital parameters for five new systems as part of the Cygnus OB2 Radial Velocity Survey. Four of the new systems (MT070, MT174, MT267, and MT734 (a.k.a. VI Cygni #11) are single-lined spectroscopic binaries while one (MT103) is a double-lined system (B1V+B2V). MT070 is noteworthy as the longest period system yet measured in Cyg OB2, with P=6.2 yr. The other four systems have periods ranging between 4 and 73 days. MT174 is noteworthy for having a probable mass ratio q<0.1, making it a candidate progenitor to a low-mass X-ray binary. These measurements bring the total number of massive binaries in Cyg OB2 to 25, the most currently known in any single cluster or association.Comment: Accepted for publication in the Astrophysical Journa
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