An Approach for Improving Automatic Mouth Emotion Recognition

The study proposes and tests a technique for automated emotion recognition through mouth detection via Convolutional Neural Networks (CNN), meant to be applied for supporting people with health disorders with communication skills issues (e.g. muscle wasting, stroke, autism, or, more simply, pain) in order to recognize emotions and generate real-time feedback, or data feeding supporting systems. The software system starts the computation identifying if a face is present on the acquired image, then it looks for the mouth location and extracts the corresponding features. Both tasks are carried out using Haar Feature-based Classifiers, which guarantee fast execution and promising performance. If our previous works focused on visual micro-expressions for personalized training on a single user, this strategy aims to train the system also on generalized faces data sets

Sharing Linkable Learning Objects with the use of Metadata and a Taxonomy Assistant for Categorization

In this work, a re-design of the Moodledata module functionalities is presented to share learning objects between e-learning content platforms, e.g., Moodle and G-Lorep, in a linkable object format. The e-learning courses content of the Drupal-based Content Management System G-Lorep for academic learning is exchanged designing an object incorporating metadata to support the reuse and the classification in its context. In such an Artificial Intelligence environment, the exchange of Linkable Learning Objects can be used for dialogue between Learning Systems to obtain information, especially with the use of semantic or structural similarity measures to enhance the existent Taxonomy Assistant for advanced automated classification

Kinematics and Kinetics of Bulgarian-Bag-Overloaded Sprints in Young Athletes

Background: Eective sprinting requires large acceleration capabilities. To accelerate, large amount of force must be produced and applied eectively. The use of dierent implements such as sleds and vests can increase the amount of force produced and alter sprinting eectiveness. We propose the use of increasing overload via the Bulgarian Bag (BB) as a means to modify athletes\u2019 sprint and acutely increase force and power production. Methods: 24 young athletes performed three sprints over 20 m in three dierent conditions: unloaded (BW) and loaded with BB weighing 2.5% (BB2.5) and 5% (BB5) of the athlete\u2019s body mass. Sprint times at 2.5, 5, 10, 15, and 20 m were acquired and used to compute the force\u2013velocity relationship for the sprints. Maximal velocity (V0), peak force (F0), peak power (PP), and decrease in ratio of force (DRF) were computed. Results: the additional load caused a decrease in sprint times (p < 0.05) and V0 (p = 0.028), conversely no dierences were found for F0 (p = 0.21), PP (p = 0.50), and DRF (p = 0.83). Conclusions: Based on those findings, BB can be an alternative method to eectively overload sprint training toward improving sprinting performance

Towards a learning-based performance modeling for accelerating Deep Neural Networks

Emerging applications such as Deep Learning are often data-driven, thus traditional approaches based on auto-tuners are not performance effective across the wide range of inputs used in practice. In the present paper, we start an investigation of predictive models based on machine learning techniques in order to optimize Convolution Neural Networks (CNNs). As a use-case, we focus on the ARM Compute Library which provides three different implementations of the convolution operator at different numeric precision. Starting from a collation of benchmarks, we build and validate models learned by Decision Tree and naive Bayesian classifier. Preliminary experiments on Midgard-based ARM Mali GPU show that our predictive model outperforms all the convolution operators manually selected by the library

A case of dengue type 3 virus infection imported from Africa to Italy, October 2009.

In October 2009, a traveller returning from Africa to Italy was hospitalised with symptoms suggestive of a haemorrhagic fever of unknown origin. The patient was immediately placed in a special biocontainment unit until laboratory investigations confirmed the infection to be caused by a dengue serotype 3 virus. This case reasserts the importance of returning travellers as sentinels of unknown outbreaks occurring in other countries, and highlights how the initial symptoms of dengue fever resemble those of other haemorrhagic fevers, hence the importance of prompt isolation of patients until a final diagnosis is reached

Prescription appropriateness of anti-diabetes drugs in elderly patients hospitalized in a clinical setting: evidence from the REPOSI Register

Diabetes is an increasing global health burden with the highest prevalence (24.0%) observed in elderly people. Older diabetic adults have a greater risk of hospitalization and several geriatric syndromes than older nondiabetic adults. For these conditions, special care is required in prescribing therapies including anti- diabetes drugs. Aim of this study was to evaluate the appropriateness and the adherence to safety recommendations in the prescriptions of glucose-lowering drugs in hospitalized elderly patients with diabetes. Data for this cross-sectional study were obtained from the REgistro POliterapie-Società Italiana Medicina Interna (REPOSI) that collected clinical information on patients aged ≥ 65 years acutely admitted to Italian internal medicine and geriatric non-intensive care units (ICU) from 2010 up to 2019. Prescription appropriateness was assessed according to the 2019 AGS Beers Criteria and anti-diabetes drug data sheets.Among 5349 patients, 1624 (30.3%) had diagnosis of type 2 diabetes. At admission, 37.7% of diabetic patients received treatment with metformin, 37.3% insulin therapy, 16.4% sulfonylureas, and 11.4% glinides. Surprisingly, only 3.1% of diabetic patients were treated with new classes of anti- diabetes drugs. According to prescription criteria, at admission 15.4% of patients treated with metformin and 2.6% with sulfonylureas received inappropriately these treatments. At discharge, the inappropriateness of metformin therapy decreased (10.2%, P < 0.0001). According to Beers criteria, the inappropriate prescriptions of sulfonylureas raised to 29% both at admission and at discharge. This study shows a poor adherence to current guidelines on diabetes management in hospitalized elderly people with a high prevalence of inappropriate use of sulfonylureas according to the Beers criteria

Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker initiation on organ support-free days in patients hospitalized with COVID-19

IMPORTANCE Overactivation of the renin-angiotensin system (RAS) may contribute to poor clinical outcomes in patients with COVID-19. Objective To determine whether angiotensin-converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB) initiation improves outcomes in patients hospitalized for COVID-19. DESIGN, SETTING, AND PARTICIPANTS In an ongoing, adaptive platform randomized clinical trial, 721 critically ill and 58 non–critically ill hospitalized adults were randomized to receive an RAS inhibitor or control between March 16, 2021, and February 25, 2022, at 69 sites in 7 countries (final follow-up on June 1, 2022). INTERVENTIONS Patients were randomized to receive open-label initiation of an ACE inhibitor (n = 257), ARB (n = 248), ARB in combination with DMX-200 (a chemokine receptor-2 inhibitor; n = 10), or no RAS inhibitor (control; n = 264) for up to 10 days. MAIN OUTCOMES AND MEASURES The primary outcome was organ support–free days, a composite of hospital survival and days alive without cardiovascular or respiratory organ support through 21 days. The primary analysis was a bayesian cumulative logistic model. Odds ratios (ORs) greater than 1 represent improved outcomes. RESULTS On February 25, 2022, enrollment was discontinued due to safety concerns. Among 679 critically ill patients with available primary outcome data, the median age was 56 years and 239 participants (35.2%) were women. Median (IQR) organ support–free days among critically ill patients was 10 (–1 to 16) in the ACE inhibitor group (n = 231), 8 (–1 to 17) in the ARB group (n = 217), and 12 (0 to 17) in the control group (n = 231) (median adjusted odds ratios of 0.77 [95% bayesian credible interval, 0.58-1.06] for improvement for ACE inhibitor and 0.76 [95% credible interval, 0.56-1.05] for ARB compared with control). The posterior probabilities that ACE inhibitors and ARBs worsened organ support–free days compared with control were 94.9% and 95.4%, respectively. Hospital survival occurred in 166 of 231 critically ill participants (71.9%) in the ACE inhibitor group, 152 of 217 (70.0%) in the ARB group, and 182 of 231 (78.8%) in the control group (posterior probabilities that ACE inhibitor and ARB worsened hospital survival compared with control were 95.3% and 98.1%, respectively). CONCLUSIONS AND RELEVANCE In this trial, among critically ill adults with COVID-19, initiation of an ACE inhibitor or ARB did not improve, and likely worsened, clinical outcomes. TRIAL REGISTRATION ClinicalTrials.gov Identifier: NCT0273570