489 research outputs found

    Null type instrument for simplifying two dimensional field plotting

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    Vacuum tube bridge operates in two modes, tracing and fixed potential. It reduces plotting time by fifty percent and improves measurement precision

    The effects of mindfulness techniques on empathy and emotional control

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    Schools’ reaction to bullying is often just that; reactive, rather than proactive. Bullying is reported and then the school takes action in one of two ways. The perpetrator is punished or the victim is supported. Sometimes schools do both. What schools are frequently missing from this equation is that no one supports the student who engaged in the bullying behavior. Research tells us that there are negative effects for all students involved in bullying. Yet few work to support the students who engage in bullying behavior. Not only would this help prevent negative effects for the individual student, it may help to prevent future bullying from taking place. The following study is designed to investigate the link between mindfulness practices and common characteristics of students who engage in bullying: lack of empathy and emotional control. A group of five fifth graders in Cleveland County Schools were referred by teachers, counselors, and administrators to participate in a small group using a modified version of the MindUP curriculum. After the intervention group, students indicated more awareness of their own behavior, an increase in empathy, and in increase in emotional control

    Instrument for measuring potentials on two dimensional electric field plots Patent

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    Instrument for measuring potentials on two dimensional electric field plo

    A copper-thiolate polynuclear cluster in the ACE1 transcription factor.

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    Measurement and comparison of individual external doses of high-school students living in Japan, France, Poland and Belarus -- the "D-shuttle" project --

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    Twelve high schools in Japan (of which six are in Fukushima Prefecture), four in France, eight in Poland and two in Belarus cooperated in the measurement and comparison of individual external doses in 2014. In total 216 high-school students and teachers participated in the study. Each participant wore an electronic personal dosimeter "D-shuttle" for two weeks, and kept a journal of his/her whereabouts and activities. The distributions of annual external doses estimated for each region overlap with each other, demonstrating that the personal external individual doses in locations where residence is currently allowed in Fukushima Prefecture and in Belarus are well within the range of estimated annual doses due to the background radiation level of other regions/countries

    Mutation in utp15 Disrupts Vascular Patterning in a p53-Dependent Manner in Zebrafish Embryos

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    Angiogenesis is the process by which the highly branched and functional vasculature arises from the major vessels, providing developing tissues with nutrients, oxygen, and removing metabolic waste. During embryogenesis, vascular patterning is dependent on a tightly regulated balance between pro- and anti-angiogenic signals, and failure of angiogenesis leads to embryonic lethality. Using the zebrafish as a model organism, we sought to identify genes that influence normal vascular patterning.In a forward genetic screen, we identified mutant LA1908, which manifests massive apoptosis during early embryogenesis, abnormal expression of several markers of arterial-venous specification, delayed angiogenic sprouting of the intersegmental vessels (ISV), and malformation of the caudal vein plexus (CVP), indicating a critical role for LA1908 in cell survival and angiogenesis. Genetic mapping and sequencing identified a G to A transition in the splice site preceding exon 11 of utp15 in LA1908 mutant embryos. Overexpression of wild type utp15 mRNA suppresses all observed mutant phenotypes, demonstrating a causative relationship between utp15 and LA1908. Furthermore, we found that injecting morpholino oligonucleotides inhibiting p53 translation prevents cell death and rescues the vascular abnormalities, indicating that p53 is downstream of Utp15 deficiency in mediating the LA1908 phenotypes.Taken together, our data demonstrate an early embryonic effect of Utp15 deficiency on cell survival and the normal patterning of the vasculature and highlight an anti-angiogenic role of p53 in developing embryos
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