40 research outputs found

    Clinical value of 3'-deoxy-3'-[18F]fluorothymidine-positron emission tomography for diagnosis, staging and assessing therapy response in lung cancer

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    Funding This review was supported by funding provided by the Royal Embassy of Saudi Arabia, Cultural Bureau in London, UK. We also gratefully acknowledge Friends of Anchor for their generous financial support of our research. Availability of data and materials The datasets used and/or analyses during the current study are available from the corresponding author upon reasonable request.Peer reviewedPublisher PD

    Binding of αvβ3 Integrin-Specific Radiotracers Is Modulated by Both Integrin Expression Level and Activation Status

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    Open Access via Springer Compact Agreement Acknowledgements We are very grateful to Prof. Calderwood (Yale University, USA) for providing the THD DNA construct, Dr. Massimiliano Baldassarre (University of Aberdeen) for useful discussions on integrin regulation and Charlie Taylor for helping to optimise the THD transfection experiments. We thank the NHS Grampian Endowment Fund for funding this research and CRANES and the Roland Sutton Academic Trust for financial support for AA.Peer reviewedPublisher PD

    Synthesis and radio-synthesis of prospective 2-nitroimidazole hypoxia PET tracers via thiazolidine ligation with 5-fluorodeoxyribose (FDR)

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    Funding Information M.M. gratefully acknowledges SULSA (http://www.sulsa.ac.uk/) for a PhD studentship. Acknowledgment Mr Federico Toson is gratefully acknowledged for conducting preliminary experiments. Supporting information for this article is available online at https://doi.org/10.1055/s-0036-1591863.Peer reviewedPublisher PD

    Widespread tissue hypoxia dysregulates cell and metabolic pathways in SMA

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    Open Access via the Wiley Jisc Agreement Acknowledgments: SHP, EH‐G, INF, SD’A, and JMC were funded by SMA Europe (SMA UK and Prinses Beatrix Spierfonds). Thanks to Prof Andy Welch for helpful discussions on imaging.Peer reviewedPublisher PD

    Enzymatic radiosynthesis of a 18F-Glu-Ureido-Lys ligand for the prostate-specific membrane antigen (PSMA)

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    We thank the Engineering and Physical Sciences Research Council, UK, for a research grant (EP/M01262X/1).Peer reviewedPostprin

    Synthesis, Radiosynthesis and in vitro Studies on Novel Hypoxia PET Tracers Incorporating [18F]FDR

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    Funding Information: M.M. thanks SULSA for a PhD studentship. We gratefully acknowledge financial support from the EPSRC (grant EP/I034793/1).Peer reviewedPostprin

    [18F]ZCDD083: a PFKFB3-targeted PET tracer for atherosclerotic plaque imaging

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    Copyright © 2020 American Chemical Society. Funding We thank the European Union’s Horizon 2020 research and innovation program under the Marie Sklodowska-Curie ITNEuropean Joint Doctorate MOGLYNET (grant agreement No. 675527).Peer reviewedPostprin

    NGR Tumor-Homing Peptides : Structural Requirements for Effective APN (CD13) Targeting

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    Acknowledgements We thank The Development Trust, University of Aberdeen, for financial support and a fellowship to M.P.Peer reviewedPublisher PD

    Hypoxia PET/CT and Colorectal Cancer : A Case Report

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    Funding: Funding for the pilot study was provided by the Colorectal Study Fund, a NHSG endowment fund number: NER 11482.Peer reviewedPublisher PD
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