27 research outputs found

    A Large Majorana-Mass From Calabi-Yau Superstring Models

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    In Calabi-Yau superstring models it is found that two large intermediate energy scales of symmetry breaking can be induced for special types of the nonrenormalizable interactions. In the models one set of SO(10)SO(10)-singlet, right-handed neutrino and their mirror chiral superfields is needed. Through the study of the minimization of the scalarpotential, the conditions for the presence of two large intermediate scales are obtained. In this scheme a Majorana-mass possibly amounts to O(10^{9 \sim 10}\gev). This large Majorana-mass solves the solar neutrino problem and also is compatible with the cosmological bound for stable light neutrinos.Comment: 12 pages, LaTeX, DPNU-93-41, AUE-06-9

    Pneumococcal polyarticular septic arthritis after a single infusion of infliximab in a rheumatoid arthritis patient: a case report

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    <p>Abstract</p> <p>Introduction</p> <p>We present a case of <it>Streptococcus pneumoniae </it>polyarticular septic arthritis in a patient with rheumatoid arthritis receiving a single infusion of infliximab.</p> <p>Case presentation</p> <p>A 38-year-old Japanese man with a 5-year history of seronegative rheumatoid arthritis had previously received sulphasalazine and methotrexate therapies and was on regular low-dose prednisolone therapy. Despite these treatments, his disease activity remained high and infliximab was introduced in addition to methotrexate, prednisolone, and folic acid. However, he was admitted to hospital with a fever of 40.6°C, chills, and polyarthralgia eight days after the first infusion of infliximab. His joints were swollen, painful, and warm. Laboratory data showed marked acute inflammation. He was diagnosed with bacterial septic polyarthritis, and emergency surgical joint lavage and drainage was performed at the knees along with needle aspiration and lavage of the ankles and right wrist. He was then given intravenous antibiotic therapy for 31 days. He made a good recovery and was discharged on day 37.</p> <p>Conclusions</p> <p>We believe this is the first reported case of severe pneumococcal septic arthritis requiring hospitalization in a patient treated with infliximab. <it>S. pneumonia </it>is now a well-recognized but uncommon cause of polyarticular septic arthritis that can lead to cessation of therapy, as in our patient's case.</p

    EFFECTS OF SOIL STRUCTURE ON COMPRESSION CURVE FOR UNSATURATED SOIL AFTER SOAKING PROCESS

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