303 research outputs found
Key Role of Defects in Thermoelectric Performance of TiMSn (M = Ni, Pd, and Pt) Half-Heusler Alloys
Sowing times influence canola grain yield and oil quality.
Titulo em português: Influência de épocas de semeadura na produtividade e qualidade de óleo de canola
Do best-selected strains perform table olive fermentation better than undefined biodiverse starters? A comparative study
Twenty-seven Lactobacillus pentosus strains, and the undefined starter for table olives from which they were isolated, were characterised for their technological properties: tolerance to low temperature, high salt concentration, alkaline pH, and olive leaf extract; acidifying ability; oleuropein degradation; hydrogen peroxide and lactic acid production. Two strains with appropriate technological properties were selected. Then, table olive fermentation in vats, with the original starter, the selected strains, and without starter (spontaneous fermentation) were compared. Starters affected some texture profile parameters. The undefined culture resulted in the most effective Enterobacteriaceae reduction, acidification and olive debittering, while the selected strains batch showed the lowest antioxidant activity. Our results show that the best candidate strains cannot guarantee better fermentation performance than the undefined biodiverse mix from which they originate
Konstruksi Makna Lansia pada Dunia Kerja dalam Film The Intern
Penelitian ini bertujuan untuk mengetahui Konstruksi makna lansia pada dunia kerja dalam film The Intern. Penelitian ini menggunakan metode Analisis Semiotika John Fiske dengan memakai kode-kode sosial John Fiske yaitu Level Realitas, Level Representasi dan Level Ideologi. Hasil penelitian yang diperoleh dari penelitian ini berdasarkan kode televisi yaitu, pada level realitas konstruksi makna lansia yang dibentuk adalah seorang lansia memiliki kecendrungan untuk tampil formal dalam berbagai kesempatan. Seorang lansia juga masih memiliki kemampuan untuk mengurus dirinya sendiri dan bekerja untuk memberikan sisa-sisa kemampuannya. Banyaknya pengalaman yang dimiliki membantu dalam memecahkan berbagai persoalan yang sedang terjadi. Pada level representasi konstruksi makana lansia yangt dibentuk adalah seorang lansia masih memiliki hasrat untuk memberikan kemampuan terbaiknya dan beradaptasi dengan perkembangan zaman (teknologi). Lansia membutuhkan penerimaan dalam lingkungan di mana dirinya berada sehingga memudahkan proses beradaptasi.Pada level ideologi konstruksi makna lansia yang dibentuk adalah seorang lansia memiliki sikap rendah hati dan bersedia membantu dan bekerja sebaik mungkin dalam lingkungannya. Lansia memiliki prinsip kerja yang dijunjung tinggi oleh dirinya. Selain itu seorang lansia bersedia mendengarkan arahan agar memudahkan dirinya untuk beradaptasi terhadap lingkungan barunya
Cardiometabolic effects of a novel SIRT1 activator, SRT2104, in people with type 2 diabetes mellitus
Background: The cardiometabolic effects of SRT2104,
a novel SIRT1 activator, were investigated in people with
type 2 diabetes mellitus (T2DM).
Methods: Fifteen adults with T2DM underwent a
randomised, double-blind, placebo-controlled cross-over
trial and received 28 days of oral SRT2104 (2.0 g/day)
or placebo. Forearm vasodilatation (measured during
intrabrachial bradykinin, acetylcholine and sodium
nitroprusside infusions) as well as markers of glycaemic
control, lipid profile, plasma fibrinolytic factors, and
markers of platelet-monocyte activation, were measured
at baseline and at the end of each treatment period.
Results: Lipid profile and platelet-monocyte
activation were similar in both treatment arms
(p>0.05 for all). Forearm vasodilatation was
similar on exposure to acetylcholine and sodium
nitroprusside (p>0.05,respectively). Bradykinin-induced
vasodilatation was less during treatment with SRT2104
versus placebo (7.753vs9.044, respectively, mean
difference=−1.291,(95% CI −2.296 to −0.285, p=0.012)).
Estimated net plasminogen activator inhibitor type 1
antigen release was reduced in the SRT2104 arm versus
placebo (mean difference=−38.89 ng/100mL tissue/
min, (95%CI −75.47, to –2.305, p=0.038)). There were
no differences in other plasma fibrinolytic factors (p>0.05
for all). After 28 days, SRT2104 exposure was associated
with weight reduction (−0.93 kg (95% CI −1.72 to −0.15),
p=0.0236), and a rise in glycated haemoglobin (5 mmol/
mol or 0.48% (0.26 to 0.70), p=0.004)
Conclusions: In people with T2DM, SRT2104 had
inconsistent, predominantly neutral effects on endothelial
and fibrinolytic function, and no discernible effect on lipids
or platelet function. In contrast, weight loss was induced
along with deterioration in glycaemic control, suggestive of
potentially important metabolic effects.
Clinical trial registration: NCT01031108; Results
Soil-transmitted helminth infections and nutritional indices among Filipino schoolchildren
BACKGROUND: Soil-transmitted helminth (STH) infections are still prevalent among schoolchildren in the Philippines. We evaluated the risk factors associated with STH and the relationship between STH and nutritional indices among schoolchildren aged 9-10 years in Laguna province, the Philippines. METHODS: We used the baseline data from 40 schools enrolled in a randomised controlled trial of the Magic Glasses Philippines health education package. Data on demographic and socio-economic variables, and STH related knowledge, attitudes and practices, were obtained through a questionnaire. Stool samples were collected and assessed for STH egg presence using the Kato-Katz technique. Haemoglobin levels and height and weight of study participants were also determined. The generalized estimating equations approach was used to construct logistic regression models to assess STH-associated risk factors, and the association between any STH infection and anaemia, child stunting, wasting and being underweight. The trial is registered with the Australian New Zealand Clinical Trials Registry (ACTRN12616000508471). FINDINGS: Among 1,689 schoolchildren, the prevalence of any STH was 23%. The prevalence of anaemia, stunting, being underweight and wasting was 13%, 20.2%, 19% and 9.5%, respectively. Age, socio-economic status, rural/urban classification of schools and knowledge of STH were significant risk factors for acquiring a STH infection. Moreover, infections with any STH were significantly associated with stunting (P = <0.001) and being underweight (P = <0.003), but not wasting (P = 0.375) or anaemia (P = 0.462) after controlling for confounding covariates. CONCLUSION: The study findings emphasise the need for sustainable deworming in tandem with other measures such as the provision of health education, improvements in sanitation and hygiene, and nutritional programs in order to control STH infections and improve morbidity outcomes in schoolchildren. TRIAL REGISTRATION: Australian New Zealand Clinical Trials Registry (ACTRN12616000508471)
Produtividade de híbridos de canola em relação a diferentes épocas de semeadura na região oeste do Paraná.
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