75 research outputs found
The Effect of Manufacturing Firms' Spatial Distributions and Entrepreneurships on the Productivity of Manufacturing Industries: An Empirical Study on Korean Case
In this paper, the spatial distributions of firm and entrepreneurship were investigated in relation with the productivity. To analyze the effect of manufacturing firms' detailed distribution patterns on the productivity of manufacturing industries, micro geographic data were used, which avoids systematic problems relating scales and borders of box unit that is administrative territories. First of all, agglomeration distances for every sub-industries were estimated, that is spatial boundaries of localization effect. Three main variables relating spatial distribution patterns of firms in same industrial classification, that are the number of firms, the average distance to other firms and disperse index from standard deviation of firms' Euclidian coordinates, are computed from Euclidian coordinates of firms in the agglomeration boundaries. Also, we checked the relationship between Entrepreneurships and productivity. And mixed effects were checked. These tests were applied to an exhaustive manufacturing firms data-set of Korea including Seoul Metropolitan Area provided by NSO. We can predict that for most sub-industries, (i) the number of firms of the same industrial classification in the agglomeration boundary has positive effect on the productivity, (ii) the average distance to other firms has positive effect below the specific distance and negative effect beyond that, and (iii) the more disperse the firms are, productivity gets decrease
Adipocyte lipid synthesis coupled to neuronal control of thermogenic programming
BACKGROUND: The de novo biosynthesis of fatty acids (DNL) through fatty acid synthase (FASN) in adipocytes is exquisitely regulated by nutrients, hormones, fasting, and obesity in mice and humans. However, the functions of DNL in adipocyte biology and in the regulation of systemic glucose homeostasis are not fully understood.
METHODS and RESULTS: Here we show adipocyte DNL controls crosstalk to localized sympathetic neurons that mediate expansion of beige/brite adipocytes within inguinal white adipose tissue (iWAT). Induced deletion of FASN in white and brown adipocytes of mature mice (iAdFASNKO mice) enhanced glucose tolerance, UCP1 expression, and cAMP signaling in iWAT. Consistent with induction of adipose sympathetic nerve activity, iAdFASNKO mice displayed markedly increased neuronal tyrosine hydroxylase (TH) and neuropeptide Y (NPY) content in iWAT. In contrast, brown adipose tissue (BAT) of iAdFASNKO mice showed no increase in TH or NPY, nor did FASN deletion selectively in brown adipocytes (UCP1-FASNKO mice) cause these effects in iWAT.
CONCLUSIONS: These results demonstrate that downregulation of fatty acid synthesis via FASN depletion in white adipocytes of mature mice can stimulate neuronal signaling to control thermogenic programming in iWAT
The validation of Implicit Association Test measures for smartphone and Internet addiction in at-risk children and adolescents
Background: Potential concerns are increasing that smartphone and Internet addictions may have deleterious effects on the mental health. Despite the recognition of the important role that implicit associations may have over explicit processes in addiction, such implicit associations have not been comprehensively investigated with respect to Internet addiction. Therefore, we modified the Implicit Association Test (IAT) for smartphone and Internet addictions and investigated its
validity in children and adolescents. Methods: In this experimental study, 78 at-risk children and adolescents ranging in age from 7 to 17 years completed an IAT modified with pictures captured from the most popular Internet games among youth. Furthermore, measures of Internet and smartphone addictions, mental health and problem behaviors, impulsive tendencies, self-esteem, daily stress, and quality of life were assessed simultaneously. Results: Significant correlations were found between IAT D2SD scores and standardized scales for Internet (r = .28, p < .05) and smartphone (r = .33, p < .01) addictions. There were no significant correlations between IAT parameters and other scales measuring the
constructs that are less relevant to the features of addiction, such as daily stress levels, impulsivity, and quality of life. Multiple regression analysis revealed that the IAT D2SD was independently and positively associated with smartphone addiction (p = .03) after controlling for other clinical correlates. Conclusions: This study demonstrated good convergent and discriminant validity of this IAT as a novel measurement relating to Internet and smartphone addictions. Further longitudinal and prospective studies are needed to evaluate its potential utility in clinical and community settings
A novel sphingosylphosphorylcholine and sphingosine-1-phosphate receptor 1 antagonist, KRO-105714, for alleviating atopic dermatitis
Background
Atopic dermatitis (eczema) is a type of inflammation of the skin, which presents with itchy, red, swollen, and cracked skin. The high global incidence of atopic dermatitis makes it one of the major skin diseases threatening public health. Sphingosylphosphorylcholine (SPC) and sphingosine-1-phosphate (S1P) act as pro-inflammatory mediators, as an angiogenesis factor and a mitogen in skin fibroblasts, respectively, both of which are important biological responses to atopic dermatitis. The SPC level is known to be elevated in atopic dermatitis, resulting from abnormal expression of sphingomyelin (SM) deacylase, accompanied by a deficiency in ceramide. Also, S1P and its receptor, sphingosine-1-phosphate receptor 1 (S1P1) are important targets in treating atopic dermatitis.
Results
In this study, we found a novel antagonist of SPC and S1P1, KRO-105714, by screening 10,000 compounds. To screen the compounds, we used an SPC-induced cell proliferation assay based on a high-throughput screening (HTS) system and a human S1P1 protein-based [35S]-GTPγS binding assay. In addition, we confirmed the inhibitory effects of KRO-105714 on atopic dermatitis through related cell-based assays, including a tube formation assay, a cell migration assay, and an ELISA assay on inflammatory cytokines. Finally, we confirmed that KRO-105714 alleviates atopic dermatitis symptoms in a series of mouse models.
Conclusions
Taken together, our data suggest that SPC and S1P1 antagonist KRO-105714 has the potential to alleviate atopic dermatitis.This work was supported by a grant from the Korea Research Council for Industrial Science and Technology (KK-1933-20) to HC, under the industrial infrastructure program for fundamental technologies and Korea Institute for Advancement of Technology through the Inter-ER Cooperation Projects (R0002017) which are funded by the Ministry of Trade, Industry & Energy, Korea to YDG
A Universal Power-law Prescription for Variability from Synthetic Images of Black Hole Accretion Flows
We present a framework for characterizing the spatiotemporal power spectrum of the variability expected from the horizon-scale emission structure around supermassive black holes, and we apply this framework to a library of general relativistic magnetohydrodynamic (GRMHD) simulations and associated general relativistic ray-traced images relevant for Event Horizon Telescope (EHT) observations of Sgr A*. We find that the variability power spectrum is generically a red-noise process in both the temporal and spatial dimensions, with the peak in power occurring on the longest timescales and largest spatial scales. When both the time-averaged source structure and the spatially integrated light-curve variability are removed, the residual power spectrum exhibits a universal broken power-law behavior. On small spatial frequencies, the residual power spectrum rises as the square of the spatial frequency and is proportional to the variance in the centroid of emission. Beyond some peak in variability power, the residual power spectrum falls as that of the time-averaged source structure, which is similar across simulations; this behavior can be naturally explained if the variability arises from a multiplicative random field that has a steeper high-frequency power-law index than that of the time-averaged source structure. We briefly explore the ability of power spectral variability studies to constrain physical parameters relevant for the GRMHD simulations, which can be scaled to provide predictions for black holes in a range of systems in the optically thin regime. We present specific expectations for the behavior of the M87* and Sgr A* accretion flows as observed by the EHT
The Event Horizon Telescope Image of the Quasar NRAO 530
We report on the observations of the quasar NRAO 530 with the Event Horizon Telescope (EHT) on 2017 April 5−7, when NRAO 530 was used as a calibrator for the EHT observations of Sagittarius A*. At z = 0.902, this is the most distant object imaged by the EHT so far. We reconstruct the first images of the source at 230 GHz, at an unprecedented angular resolution of ∼20 μas, both in total intensity and in linear polarization (LP). We do not detect source variability, allowing us to represent the whole data set with static images. The images reveal a bright feature located on the southern end of the jet, which we associate with the core. The feature is linearly polarized, with a fractional polarization of ∼5%–8%, and it has a substructure consisting of two components. Their observed brightness temperature suggests that the energy density of the jet is dominated by the magnetic field. The jet extends over 60 μas along a position angle ∼ −28°. It includes two features with orthogonal directions of polarization (electric vector position angle), parallel and perpendicular to the jet axis, consistent with a helical structure of the magnetic field in the jet. The outermost feature has a particularly high degree of LP, suggestive of a nearly uniform magnetic field. Future EHT observations will probe the variability of the jet structure on microarcsecond scales, while simultaneous multiwavelength monitoring will provide insight into the high-energy emission origin
The Event Horizon Telescope image of the Quasar NRAO 530
We report on the observations of the quasar NRAO 530 with the Event Horizon Telescope (EHT) on 2017 April 5−7,
when NRAO 530 was used as a calibrator for the EHT observations of Sagittarius A*. At z=0.902, this is the most
distant object imaged by the EHT so far. We reconstruct the first images of the source at 230 GHz, at an unprecedented
angular resolution of ∼20 μas, both in total intensity and in linear polarization (LP).We do not detect source variability,
allowing us to represent the whole data set with static images. The images reveal a bright feature located on the southern
end of the jet, which we associate with the core. The feature is linearly polarized, with a fractional polarization of ∼5%–
8%, and it has a substructure consisting of two components. Their observed brightness temperature suggests that the
energy density of the jet is dominated by the magnetic field. The jet extends over 60 μas along a position angle∼−28°.
It includes two features with orthogonal directions of polarization (electric vector position angle), parallel and
perpendicular to the jet axis, consistent with a helical structure of the magnetic field in the jet. The outermost feature has
a particularly high degree of LP, suggestive of a nearly uniform magnetic field. Future EHT observations will probe the
variability of the jet structure on microarcsecond scales, while simultaneous multiwavelength monitoring will provide
insight into the high-energy emission origin.ACKNOWLEDGEMENTS : The Event Horizon Telescope Collaboration thanks the
following organizations and programs: the Academia Sinica;
the Academy of Finland (projects 274477, 284495, 312496,
315721); the Agencia Nacional de Investigación y Desarrollo
(ANID), Chile via NCN19_058 (TITANs) and Fondecyt
1221421, the Alexander von Humboldt Stiftung; an Alfred P.
Sloan Research Fellowship; Allegro, the European ALMA
Regional Centre node in the Netherlands, the NL astronomy
research network NOVA and the astronomy institutes of the
University of Amsterdam, Leiden University and Radboud University; the ALMA North America Development Fund; the
black hole Initiative, which is funded by grants from the John
Templeton Foundation and the Gordon and Betty Moore
Foundation (although the opinions expressed in this work are
those of the author(s) and do not necessarily reflect the views of
these Foundations); Chandra DD7-18089X and TM6-17006X;
the China Scholarship Council; China Postdoctoral Science
Foundation fellowship (2020M671266); Consejo Nacional de
Ciencia y Tecnología (CONACYT, Mexico, projects U0004-
246083, U0004-259839, F0003-272050, M0037-279006,
F0003-281692, 104497, 275201, 263356); the Consejería de
Economía, Conocimiento, Empresas y Universidad of the Junta
de Andalucía (grant P18-FR-1769), the Consejo Superior de
Investigaciones Científicas (grant 2019AEP112); the Delaney
Family via the Delaney Family John A. Wheeler Chair at
Perimeter Institute; Dirección General de Asuntos del Personal
Académico-Universidad Nacional Autónoma de México
(DGAPA-UNAM, projects IN112417 and IN112820); the
Dutch Organization for Scientific Research (NWO) VICI
award (grant 639.043.513) and grant OCENW.KLEIN.113;
the Dutch National Supercomputers, Cartesius and Snellius
(NWO Grant 2021.013); the EACOA Fellowship awarded by
the East Asia Core Observatories Association, which consists
of the Academia Sinica Institute of Astronomy and Astrophysics,
the National Astronomical Observatory of Japan,
Center for Astronomical Mega-Science, Chinese Academy of
Sciences, and the Korea Astronomy and Space Science
Institute; the European Research Council (ERC) Synergy
Grant “BlackHoleCam: Imaging the Event Horizon of Black
Holes” (grant 610058); the European Union Horizon 2020
research and innovation program under grant agreements
RadioNet (No. 730562) and M2FINDERS (No. 101018682);
the Horizon ERC Grants 2021 program under grant agreement
No. 101040021; the Generalitat Valenciana postdoctoral grant
APOSTD/2018/177 and GenT Program (project CIDEGENT/
2018/021); MICINN Research Project PID2019-108995GBC22;
the European Research Council for advanced grant
“JETSET: Launching, propagation and emission of relativistic
jets from binary mergers and across mass scales” (grant No.
884631); the Institute for Advanced Study; the Istituto
Nazionale di Fisica Nucleare (INFN) sezione di Napoli,
iniziative specifiche TEONGRAV; the International Max
Planck Research School for Astronomy and Astrophysics at
the Universities of Bonn and Cologne; DFG research grant “Jet
physics on horizon scales and beyond” (grant No. FR 4069/2-
1); Joint Columbia/Flatiron Postdoctoral Fellowship, research
at the Flatiron Institute is supported by the Simons Foundation;
the Japan Ministry of Education, Culture, Sports, Science and
Technology (MEXT; grant JPMXP1020200109); the Japanese
Government (Monbukagakusho: MEXT) Scholarship; the
Japan Society for the Promotion of Science (JSPS) Grant-in-
Aid for JSPS Research Fellowship (JP17J08829); the Joint
Institute for Computational Fundamental Science, Japan; the
Key Research Program of Frontier Sciences, Chinese Academy
of Sciences (CAS, grants QYZDJ-SSW-SLH057, QYZDJS
SW-SYS008, ZDBS-LY-SLH011); the Leverhulme Trust
Early Career Research Fellowship; the Max-Planck-Gesell
schaft (MPG); the Max Planck Partner Group of the MPG and
the CAS; the MEXT/JSPS KAKENHI (grants 18KK0090,
JP21H01137, JP18H03721, JP18K13594, 18K03709, JP19K1
4761, 18H01245, 25120007); the Malaysian Fundamental
Research Grant Scheme (FRGS) FRGS/1/2019/STG02/
UM/02/6; the MIT International Science and Technology
Initiatives (MISTI) Funds; the Ministry of Science and
Technology (MOST) of Taiwan (103-2119-M-001-010-MY2,
105-2112-M-001-025-MY3, 105-2119-M-001-042, 106-2112-
M-001-011, 106-2119-M-001-013, 106-2119-M-001-027, 106-
2923-M-001-005, 107-2119-M-001-017, 107-2119-M-001-
020, 107-2119-M-001-041, 107-2119-M-110-005, 107-2923-
M-001-009, 108-2112-M-001-048, 108-2112-M-001-051, 108-
2923-M-001-002, 109-2112-M-001-025, 109-2124-M-001-
005, 109-2923-M-001-001, 110-2112-M-003-007-MY2, 110-
2112-M-001-033, 110-2124-M-001-007, and 110-2923-M-
001-001); the Ministry of Education (MoE) of Taiwan Yushan
Young Scholar Program; the Physics Division, National Center
for Theoretical Sciences of Taiwan; the National Aeronautics
and Space Administration (NASA, Fermi Guest Investigator
grants 80NSSC20K1567 and 80NSSC22K1571, NASA Astrophysics
Theory Program grant 80NSSC20K0527, NASA
NuSTAR award 80NSSC20K0645); NASA Hubble Fellowship
grants HST-HF2-51431.001-A, HST-HF2-51482.001-A
awarded by the Space Telescope Science Institute, which is
operated by the Association of Universities for Research in
Astronomy, Inc., for NASA, under contract NAS5-26555; the
National Institute of Natural Sciences (NINS) of Japan; the
National Key Research and Development Program of China
(grant 2016YFA0400704, 2017YFA0402703, 2016YFA040
0702); the National Science Foundation (NSF, grants AST-
0096454, AST-0352953, AST-0521233, AST-0705062, AST-
0905844, AST-0922984, AST-1126433, AST-1140030, DGE-
1144085, AST-1207704, AST-1207730, AST-1207752, MRI-
1228509, OPP-1248097, AST-1310896, AST-1440254, AST-
1555365, AST-1614868, AST-1615796, AST-1715061, AST-
1716327, AST-1716536, OISE-1743747, AST-1816420, AST-
1935980, AST-2034306); NSF Astronomy and Astrophysics
Postdoctoral Fellowship (AST-1903847); the Natural Science
Foundation of China (grants 11650110427, 10625314,
11721303, 11725312, 11873028, 11933007, 11991052, 119910
53, 12192220, 12192223); the Natural Sciences and Engineering
Research Council of Canada (NSERC, including a
Discovery grant and the NSERC Alexander Graham Bell
Canada Graduate Scholarships-Doctoral Program); the National
Youth Thousand Talents Program of China; the National
Research Foundation of Korea (the Global PhD Fellowship
grant: grants NRF-2015H1A2A1033752, the Korea Research
Fellowship Program: NRF-2015H1D3A1066561, Brain
Pool Program: 2019H1D3A1A01102564, Basic Research
Support grant 2019R1F1A1059721, 2021R1A6A3A01086420,
2022R1C1C1005255); Netherlands Research School for
Astronomy (NOVA) Virtual Institute of Accretion (VIA)
postdoctoral fellowships; Onsala Space Observatory (OSO)
national infrastructure, for the provisioning of its facilities/
observational support (OSO receives funding through the
Swedish Research Council under grant 2017-00648); the
Perimeter Institute for Theoretical Physics (research at Perimeter
Institute is supported by the Government of Canada through the
Department of Innovation, Science and Economic Development
and by the Province of Ontario through the Ministry of
Research, Innovation and Science); the Princeton Gravity
Initiative; the Spanish Ministerio de Ciencia e Innovación
(grants PGC2018-098915-B-C21, AYA2016-80889-P, PID
2019-108995GB-C21, PID2020-117404GB-C21); the University
of Pretoria for financial aid in the provision of the new
Cluster Server nodes and SuperMicro (USA) for a SEEDING grant approved toward these nodes in 2020; the Shanghai Pilot
Program for Basic Research, Chinese Academy of Science,
Shanghai Branch (JCYJ-SHFY-2021-013); the State Agency for
Research of the Spanish MCIU through the “Center of
Excellence Severo Ochoa” award for the Instituto de Astrofísica
de Andalucía (SEV-2017-0709); the Spinoza Prize SPI 78-409;
the South African Research Chairs Initiative, through the South
African Radio Astronomy Observatory (SARAO, grant ID
77948), which is a facility of the National Research Foundation
(NRF), an agency of the Department of Science and Innovation
(DSI) of South Africa; the Toray Science Foundation; the
Swedish Research Council (VR); the US Department of Energy
(USDOE) through the Los Alamos National Laboratory
(operated by Triad National Security, LLC, for the National
Nuclear Security Administration of the USDOE (Contract
89233218CNA000001); and the YCAA Prize Postdoctoral
Fellowship.
We thank the staff at the participating observatories,
correlation centers, and institutions for their enthusiastic
support. This paper makes use of the following ALMA data:
ADS/JAO.ALMA#2016.1.01154.V. ALMA is a partnership
of the European Southern Observatory (ESO; Europe,
representing its member states), NSF, and National Institutes
of Natural Sciences of Japan, together with National Research
Council (Canada), Ministry of Science and Technology
(MOST; Taiwan), Academia Sinica Institute of Astronomy
and Astrophysics (ASIAA; Taiwan), and Korea Astronomy and
Space Science Institute (KASI; Republic of Korea), in
cooperation with the Republic of Chile. The Joint ALMA
Observatory is operated by ESO, Associated Universities, Inc.
(AUI)/NRAO, and the National Astronomical Observatory of
Japan (NAOJ). The NRAO is a facility of the NSF operated
under cooperative agreement by AUI. This research used
resources of the Oak Ridge Leadership Computing Facility at
the Oak Ridge National Laboratory, which is supported by the
Office of Science of the U.S. Department of Energy under
contract No. DE-AC05-00OR22725. We also thank the Center
for Computational Astrophysics, National Astronomical Observatory
of Japan. The computing cluster of Shanghai VLBI
correlator supported by the Special Fund for Astronomy from
the Ministry of Finance in China is acknowledged. This work
was supported by FAPESP (Fundacao de Amparo a Pesquisa
do Estado de Sao Paulo) under grant 2021/01183-8.
APEX is a collaboration between the Max-Planck-Institut für
Radioastronomie (Germany), ESO, and the Onsala Space
Observatory (Sweden). The SMA is a joint project between the
SAO and ASIAA and is funded by the Smithsonian Institution
and the Academia Sinica. The JCMT is operated by the East
Asian Observatory on behalf of the NAOJ, ASIAA, and KASI,
as well as the Ministry of Finance of China, Chinese Academy
of Sciences, and the National Key Research and Development
Program (No. 2017YFA0402700) of China and Natural
Science Foundation of China grant 11873028. Additional
funding support for the JCMT is provided by the Science and
Technologies Facility Council (UK) and participating universities
in the UK and Canada. The LMT is a project operated
by the Instituto Nacional de Astrófisica, Óptica, y Electrónica
(Mexico) and the University of Massachusetts at Amherst
(USA). The IRAM 30 m telescope on Pico Veleta, Spain is
operated by IRAM and supported by CNRS (Centre National
de la Recherche Scientifique, France), MPG (Max-Planck-
Gesellschaft, Germany) and IGN (Instituto Geográfico
Nacional, Spain). The SMT is operated by the Arizona Radio
Observatory, a part of the Steward Observatory of the
University of Arizona, with financial support of operations
from the State of Arizona and financial support for instrumentation
development from the NSF. Support for SPT participation
in the EHT is provided by the National Science Foundation
through award OPP-1852617 to the University of Chicago.
Partial support is also provided by the Kavli Institute of
Cosmological Physics at the University of Chicago. The SPT
hydrogen maser was provided on loan from the GLT, courtesy
of ASIAA.
This work used the Extreme Science and Engineering
Discovery Environment (XSEDE), supported by NSF grant
ACI-1548562, and CyVerse, supported by NSF grants DBI-
0735191, DBI-1265383, and DBI-1743442. XSEDE Stampede2
resource at TACC was allocated through TGAST170024
and TG-AST080026N. XSEDE JetStream
resource at PTI and TACC was allocated through
AST170028. This research is part of the Frontera computing
project at the Texas Advanced Computing Center through the
Frontera Large-Scale Community Partnerships allocation
AST20023. Frontera is made possible by National Science
Foundation award OAC-1818253. This research was carried
out using resources provided by the Open Science Grid, which
is supported by the National Science Foundation and the U.S.
Department of Energy Office of Science. Additional work used
ABACUS2.0, which is part of the eScience center at Southern
Denmark University. Simulations were also performed on the
SuperMUC cluster at the LRZ in Garching, on the LOEWE
cluster in CSC in Frankfurt, on the HazelHen cluster at the
HLRS in Stuttgart, and on the Pi2.0 and Siyuan Mark-I at
Shanghai Jiao Tong University. The computer resources of the
Finnish IT Center for Science (CSC) and the Finnish
Computing Competence Infrastructure (FCCI) project are
acknowledged. This research was enabled in part by support
provided by Compute Ontario (http://computeontario.ca),
Calcul Quebec (http://www.calculquebec.ca), and Compute
Canada (http://www.computecanada.ca).
The EHTC has received generous donations of FPGA chips
from Xilinx Inc., under the Xilinx University Program. The
EHTC has benefited from technology shared under open-source
license by the Collaboration for Astronomy Signal Processing
and Electronics Research (CASPER). The EHT project is
grateful to T4Science and Microsemi for their assistance with
Hydrogen Masers. This research has made use of NASA’s
Astrophysics Data System. We gratefully acknowledge the
support provided by the extended staff of the ALMA, both from
the inception of the ALMA Phasing Project through the
observational campaigns of 2017 and 2018. We would like to
thank A. Deller and W. Brisken for EHT-specific support with
the use of DiFX. We thank Martin Shepherd for the addition of
extra features in the Difmap software that were used for the
CLEAN imaging results presented in this paper. We acknowledge
the significance and cultural reverance that Maunakea,
where the SMA and JCMT EHT stations are located, has always
held within the indigenous Hawaiian people.
SOFTWARE : DIFMAP (Shepherd 1997), Matplotlib
(Hunter 2007), DiFX (Deller et al. 2011), NumPy (van der
Walt et al. 2011), eht-imaging (Chael et al. 2016),
PolConvert (Martí-Vidal et al. 2016), SMILI (Akiyama
et al. 2017), EHT-HOPS (Blackburn et al. 2019), Themis
(Broderick et al. 2020a), DMC (Pesce 2021).https://iopscience.iop.org/journal/0004-637Xam2024PhysicsNon
First Sagittarius A* Event Horizon Telescope Results. IV. Variability, Morphology, and Black Hole Mass
In this paper we quantify the temporal variability and image morphology of the horizon-scale emission from Sgr A*, as observed by the EHT in 2017 April at a wavelength of 1.3 mm. We find that the Sgr A* data exhibit variability that exceeds what can be explained by the uncertainties in the data or by the effects of interstellar scattering. The magnitude of this variability can be a substantial fraction of the correlated flux density, reaching ∼100% on some baselines. Through an exploration of simple geometric source models, we demonstrate that ring-like morphologies provide better fits to the Sgr A* data than do other morphologies with comparable complexity. We develop two strategies for fitting static geometric ring models to the time-variable Sgr A* data; one strategy fits models to short segments of data over which the source is static and averages these independent fits, while the other fits models to the full data set using a parametric model for the structural variability power spectrum around the average source structure. Both geometric modeling and image-domain feature extraction techniques determine the ring diameter to be 51.8 ± 2.3 μas (68% credible intervals), with the ring thickness constrained to have an FWHM between ∼30% and 50% of the ring diameter. To bring the diameter measurements to a common physical scale, we calibrate them using synthetic data generated from GRMHD simulations. This calibration constrains the angular size of the gravitational radius to be 4.8−0.7+1.4 μas, which we combine with an independent distance measurement from maser parallaxes to determine the mass of Sgr A* to be 4.0−0.6+1.1×106 M ⊙
First Sagittarius A* Event Horizon Telescope Results. VI. Testing the Black Hole Metric
Astrophysical black holes are expected to be described by the Kerr metric. This is the only stationary, vacuum, axisymmetric metric, without electromagnetic charge, that satisfies Einstein’s equations and does not have pathologies outside of the event horizon. We present new constraints on potential deviations from the Kerr prediction based on 2017 EHT observations of Sagittarius A* (Sgr A*). We calibrate the relationship between the geometrically defined black hole shadow and the observed size of the ring-like images using a library that includes both Kerr and non-Kerr simulations. We use the exquisite prior constraints on the mass-to-distance ratio for Sgr A* to show that the observed image size is within ∼10% of the Kerr predictions. We use these bounds to constrain metrics that are parametrically different from Kerr, as well as the charges of several known spacetimes. To consider alternatives to the presence of an event horizon, we explore the possibility that Sgr A* is a compact object with a surface that either absorbs and thermally reemits incident radiation or partially reflects it. Using the observed image size and the broadband spectrum of Sgr A*, we conclude that a thermal surface can be ruled out and a fully reflective one is unlikely. We compare our results to the broader landscape of gravitational tests. Together with the bounds found for stellar-mass black holes and the M87 black hole, our observations provide further support that the external spacetimes of all black holes are described by the Kerr metric, independent of their mass
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