1,866 research outputs found
Nutrição, calagem e adubação.
O cultivo da bananeira demanda grandes quantidades de nutrientes para manter o bom desenvolvimento da planta e boa produção, sendo que o potássio e o nitrogênio são os mais exigidos. Em ordem decrescente, a bananeira absorve os seguintes nutrientes: a) macronutrientes - potássio (K) > nitrogênio (N) > cálcio (Cal) > magnésio (Mg) > enxofre (S) > fósforo (P); e b) micronutrientes - cloro (Cl) > manganês (Mn) > ferro (Fe) > zinco (Zn) > boro (B) > cobre (Cu). Em média, um bananal retira, por tonelada de frutos, 5,2 Kg de K; 1,9 Kg de N; 0,30 Kg de Mg; 0,23 Kg de P e 0,22 Kg de Ca. A grande exigência da bananeira e os baixos teores de nutrientes em alguns solos fazem com que seu cultivo em sistemas intensivos necessite de elevado uso de fertilizantes e água, para uma maior eficiência na absorção dos nutrientes
Fertirrigação da bananeira.
A bananeira é exigente em água nos períodos de baixa precipitação com temperaturas e evaporação elevadas. Apresenta crescimento rápido e requer, para seu desenvolvimento e produção, quantidades adequadas de água e nutrientes podem ser supridos pelo próprio solo e pelos resíduos das colheitas; no entanto, para produções economicamente rentáveis, na maioria das vezes, é necessário aplicar fertilizantes químicos ou orgânicos. A aplicação fertilizantes via água de irrigação, fertirrigação, é uma prática empregada na agricultura irrigada, constituindo-se no meio mais eficiente de nutrição, pois combina dois fatores essenciais para o cresimento, desenvolvimento e produção das plantas: água e nutrientes.bitstream/CNPMF/23999/1/circular_84.pd
New steroidal aromatase inhibitors: Suppression of estrogen-dependent breast cancer cell proliferation and induction of cell death
<p>Abstract</p> <p>Background</p> <p>Aromatase, the cytochrome P-450 enzyme (CYP19) responsible for estrogen biosynthesis, is an important target for the treatment of estrogen-dependent breast cancer. In fact, the use of synthetic aromatase inhibitors (AI), which induce suppression of estrogen synthesis, has shown to be an effective alternative to the classical tamoxifen for the treatment of postmenopausal patients with ER-positive breast cancer. New AIs obtained, in our laboratory, by modification of the A and D-rings of the natural substrate of aromatase, compounds <b>3a </b>and <b>4a</b>, showed previously to efficiently suppress aromatase activity in placental microsomes. In the present study we have investigated the effects of these compounds on cell proliferation, cell cycle progression and induction of cell death using the estrogen-dependent human breast cancer cell line stably transfected with the aromatase gene, MCF-7 aro cells.</p> <p>Results</p> <p>The new steroids inhibit hormone-dependent proliferation of MCF-7aro cells in a time and dose-dependent manner, causing cell cycle arrest in G<sub>0</sub>/G<sub>1 </sub>phase and inducing cell death with features of apoptosis and autophagic cell death.</p> <p>Conclusion</p> <p>Our <it>in vitro </it>studies showed that the two steroidal AIs, <b>3a </b>and <b>4a</b>, are potent inhibitors of breast cancer cell proliferation. Moreover, it was also shown that the antiproliferative effects of these two steroids on MCF-7aro cells are mediated by disrupting cell cycle progression, through cell cycle arrest in G<sub>0</sub>/G<sub>1 </sub>phase and induction of cell death, being the dominant mechanism autophagic cell death. Our results are important for the elucidation of the cellular effects of steroidal AIs on breast cancer.</p
Análise estrutural das folhas de Senna alata (L.) Roxb. e Senna obtusifolia L. Irvin & Barneby em microscopia eletrônica de varredura.
Taxonomic, structural diversity and carbon stocks in a gradient of island forests
Assessment of forest ecosystems and their services is seen as a key action for the advancement of biodiversity objectives, and to inform the development and implementation of related policies and planning. The Azorean forest is important for timber production, the protection of soil and water resources, and for its recreational and aesthetic value. However, its role in carbon accumulation has not been fully addressed. We assessed plant diversity, forest structure and carbon stocks in a gradient of three forest types (Natural Forest-NF; Exotic Woodland-EW and Production Forest-PF) in three of the Azores islands. We used biodiversity indices and found that NF harboured the highest plant diversity levels and PF the lowest. Diversity levels were lower for structural than for taxonomic data, particularly for PF. The highest tree carbon stock was found at EW in one of the islands, while PF consistently exhibited relatively high tree carbon stocks in the three islands. The largest soil carbon stocks were found at EW, while leaf litter carbon stocks were higher at PF. We concluded that NF play a fundamental role as plant diversity hotspots but have lower relevance as carbon stocks what might be associated with montane environmental conditions. PFs provide economic assets and act as carbon sinks, while EWs play a major role as carbon sinks in soil, but also at tree level in the oldest forests.This research was funded by Project FOREST-ECO2-Towards an Ecological and economic valorization of the Azorean Forest ACORES-01-0145-FEDER-000014-Azores 2020 PO, 2016-2019; FEDER funds through the Operational Programme for Competitiveness Factors-COMPETE and by National Funds through FCT-Foundation for Science and Technology under the UID/BIA/50027/2019 and POCI-01-0145-FEDER-006821info:eu-repo/semantics/publishedVersio
Análise de Repetibilidade em Caracteres de Arquitetura da Planta e Produção em Pinhão-manso.
O objetivo deste trabalho foi estimar os coeficientes de repetibilidade para produção de grãos, números de ramos, altura e volume de copa do pinhão-manso, nos 10 e 20 anos pós-plantio
Amphibians on the hotspot: Molecular biology and conservation in the South American Atlantic Rainforest
Amphibians are the focus of a recent debate and public attention owing to the global decline in their populations worldwide. Amphibians are one of the most threatened and poorly known groups of vertebrates in several geographic areas, even though they play a central role in their own ecosystems. At different levels, amphibians make their contribution to proper ecosystem functioning. They act as regulators of the food web and nutrient cycling, and they also provide several valuable ecosystem services, e.g., as a food source and as animal models for lab research. In this sense, it seems clear that the maintenance of amphibian diversity should be one of the major goals for the several countries where their population decline is observed. However, we are still struggling with the very first step of this process, i.e., the correct identification of the amphibian species diversity. Over the past few decades, research on molecular identification of amphibians using DNA barcoding has encountered some difficulties related to high variability in the mitochondrial genome of amphibians, and a research gap is noticeable in the literature. We herein evaluated both COI and 16S rRNA mitochondrial genes for the molecular identification of frogs and tadpoles in a large fragment of the South American Atlantic Rainforest in Rio de Janeiro, Brazil. Our results suggest that both COI and 16S rRNA are informative markers for the molecular identification of the amphibian specimens with all specimens unambiguously identified at the species level. We also made publicly available 12 new sequences of Atlantic Rainforest amphibian species for the first time, and we discussed some conservation issues related to amphibians within the Atlantic Rainforest domains in the state of Rio de Janeiro, Brazil.The authors benefited from grants provided to CFDR (304791/2010-5; 470265/2010- 8 and 302974/2015-6) from Conselho Nacional do Desenvolvimento Cientifico e Tecnologico (CNPq) and through "Cientistas do Nosso Estado" Program from FAPERJ to CFDR (process No. E-26/ 102.765.2012 E-26/202.920.2015). We would like to thank C. Haddad (Universidade Estadual Paulista) and M. L. Lyra (Universidade Estadual Paulista) for some of the specimens and the primers used in the present manuscript and L. A. Fusinatto, who kindly revised the manuscript offering helpful suggestions. FP was supported by the Portuguese Foundation for Science and Technology (FCT) [IF/01356/2012] and Northern Regional Operational Programme (NORTE2020) through the European Regional Development Fund (ERDF) [MARINFO NORTE-01-0145-FEDER- 000031]. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript
Mathematical model of brain tumour with glia-neuron interactions and chemotherapy treatment
Acknowledgements This study was possible by partial financial support from the following Brazilian government agencies: Fundação Araucária, EPSRC-EP/I032606/1 and CNPq, CAPES and Science Without Borders Program Process nos. 17656125, 99999.010583/2013-00 and 245377/2012-3.Peer reviewedPreprin
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