Pediatric Developmental Screening: Understanding and Selecting Screening Instruments

Based on a review of research on developmental screening instruments, provides a manual for selecting and applying tools for screening for both general and specific problems. Includes an interactive questionnaire that links to the recommended instrument

Airfall on Comet 67P/Churyumov–Gerasimenko

We here study the transfer process of material from one hemisphere to the other (deposition of airfall material) on an active comet nucleus, specifically 67P/Churyumov–Gerasimenko. Our goals are to: 1) quantify the thickness of the airfall debris layers and how it depends on the location of the target area, 2) determine the amount of H₂O and CO₂ ice that are lost from icy dust assemblages of different sizes during transfer through the coma, and 3) estimate the relative amount of vapor loss in airfall material after deposition in order to understand what locations are expected to be more active than others on the following perihelion approach. We use various numerical simulations, that include orbit dynamics, thermophysics of the nucleus and of individual coma aggregates, coma gas kinetics and hydrodynamics, as well as dust dynamics due to gas drag, to address these questions. We find that the thickness of accumulated airfall material varies substantially with location, and typically is of the order 0.1–1 m. The airfall material preserves substantial amounts of water ice even in relatively small (cm–sized) coma aggregates after a rather long (12 h) residence in the coma. However, CO₂ is lost within a couple of hours even in relatively large (dm–sized) aggregates, and is not expected to be an important component in airfall deposits. We introduce reachability and survivability indices to measure the relative capacity of different regions to simultaneously collect airfall and to preserve its water ice until the next perihelion passage, thereby grading their potential of contributing to comet activity during the next perihelion passage

Airfall on Comet 67P/Churyumov–Gerasimenko

We here study the transfer process of material from one hemisphere to the other (deposition of airfall material) on an active comet nucleus, specifically 67P/Churyumov–Gerasimenko. Our goals are to: 1) quantify the thickness of the airfall debris layers and how it depends on the location of the target area, 2) determine the amount of H₂O and CO₂ ice that are lost from icy dust assemblages of different sizes during transfer through the coma, and 3) estimate the relative amount of vapor loss in airfall material after deposition in order to understand what locations are expected to be more active than others on the following perihelion approach. We use various numerical simulations, that include orbit dynamics, thermophysics of the nucleus and of individual coma aggregates, coma gas kinetics and hydrodynamics, as well as dust dynamics due to gas drag, to address these questions. We find that the thickness of accumulated airfall material varies substantially with location, and typically is of the order 0.1–1 m. The airfall material preserves substantial amounts of water ice even in relatively small (cm–sized) coma aggregates after a rather long (12 h) residence in the coma. However, CO₂ is lost within a couple of hours even in relatively large (dm–sized) aggregates, and is not expected to be an important component in airfall deposits. We introduce reachability and survivability indices to measure the relative capacity of different regions to simultaneously collect airfall and to preserve its water ice until the next perihelion passage, thereby grading their potential of contributing to comet activity during the next perihelion passage

Young women's use of a microbicide surrogate: The complex influence of relationship characteristics and perceived male partners' evaluations

This is the post-print version of the article. The official published version can be found at the link below.Currently in clinical trials, vaginal microbicides are proposed as a female-initiated method of sexually transmitted infection prevention. Much of microbicide acceptability research has been conducted outside of the United States and frequently without consideration of the social interaction between sex partners, ignoring the complex gender and power structures often inherent in young women’s (heterosexual) relationships. Accordingly, the purpose of this study was to build on existing microbicide research by exploring the role of male partners and relationship characteristics on young women’s use of a microbicide surrogate, an inert vaginal moisturizer (VM), in a large city in the United States. Individual semi-structured interviews were conducted with 40 young women (18–23 years old; 85% African American; 47.5% mothers) following use of the VM during coital events for a 4 week period. Overall, the results indicated that relationship dynamics and perceptions of male partners influenced VM evaluation. These two factors suggest that relationship context will need to be considered in the promotion of vaginal microbicides. The findings offer insights into how future acceptability and use of microbicides will be influenced by gendered power dynamics. The results also underscore the importance of incorporating men into microbicide promotion efforts while encouraging a dialogue that focuses attention on power inequities that can exist in heterosexual relationships. Detailed understanding of these issues is essential for successful microbicide acceptability, social marketing, education, and use.This study was funded by a grant from National Institutes of Health (NIHU19AI 31494) as well as research awards to the first author: Friends of the Kinsey Institute Research Grant Award, Indiana University’s School of HPER Graduate Student Grant-in-Aid of Research Award, William L. Yarber Sexual Health Fellowship, and the Indiana University Graduate and Professional Student Organization Research Grant

To whom does the law speak? Canvassing a neglected picture of law’s interpretive field

Among the most common strategies underlying the so-called indeterminacy thesis is the following two-step argument: (1) that law is an interpretive practice, and that evidently legal actors more generally hold different (and competing) theories of meaning, which lead to disagreements as to what the law says (that is, as to what the law is); (2) and that, as there is no way to establish the prevalence of one particular theory of meaning over the other, indeterminacy is pervasive in law. In this paper I offer some reflections to resist this trend. In particular I claim that a proper understanding of law as an authoritative communicative enterprise sheds new light on the relation between the functioning of the law and our theories of interpretation, leading to what can be considered a neglected conclusion: the centrality of the linguistic criterion of meaning in our juridical interpretive practices. In the first part of the chapter I discuss speech-act theory in the study of law, assessing its relevance between alternative options. Then I tackle the ‘to whom does the law speak?’ question, highlighting the centrality of lay-people for our juridical practices. Lastly, I examine the consequences of this neglected fact for our interpretive theories

Sepsis in two hospitals in Rwanda: A retrospective cohort study of presentation, management, outcomes, and predictors of mortality.

PURPOSE: Few studies have assessed the presentation, management, and outcomes of sepsis in low-income countries (LICs). We sought to characterize these aspects of sepsis and to assess mortality predictors in sepsis in two referral hospitals in Rwanda. MATERIALS AND METHODS: This was a retrospective cohort study in two public academic referral hospitals in Rwanda. Data was abstracted from paper medical records of adult patients who met our criteria for sepsis. RESULTS: Of the 181 subjects who met eligibility criteria, 111 (61.3%) met our criteria for sepsis without shock and 70 (38.7%) met our criteria for septic shock. Thirty-five subjects (19.3%) were known to be HIV positive. The vast majority of septic patients (92.7%) received intravenous fluid therapy (median = 1.0 L within 8 hours), and 94.0% received antimicrobials. Vasopressors were administered to 32.0% of the cohort and 46.4% received mechanical ventilation. In-hospital mortality for all patients with sepsis was 51.4%, and it was 82.9% for those with septic shock. Baseline characteristic mortality predictors were respiratory rate, Glasgow Coma Scale score, and known HIV seropositivity. CONCLUSIONS: Septic patients in two public tertiary referral hospitals in Rwanda are young (median age = 40, IQR = 29, 59) and experience high rates of mortality. Predictors of mortality included baseline clinical characteristics and HIV seropositivity status. The majority of subjects were treated with intravenous fluids and antimicrobials. Further work is needed to understand clinical and management factors that may help improve mortality in septic patients in LICs

‘Re-reading Raphael Samuel: Politics, Personality and Performance’

For British historian Raphael Samuel, history and politics were inextricable. Best known as the founder of the history workshop movement, the controversial historian took his stance on the democratisation of history-making, becoming an outspoken advocate for public history. Despite making a significant contribution to contemporary historiography, he remains a neglected, even disparaged, figure. This paper contends that the most significant aspect of Samuel’s historical work was not one or other theory of history or argument about the past but his entire way of being an historian. Samuel embodied as much as expressed his ideas, consciously using his personality as a powerful political tool. It is further argued that conventional approaches to intellectual history, focusing on textual outputs, do not fully recognise the significance of performative modes of thinking. Theoretical approaches to performance as identity offer important insight here but can be too schematic in their view of applied and enacted thought. A biographical approach, by contrast, provides the intimate perspective necessary to fully appreciate the fluidity and complexity of such a personality. The paper first situates Samuel in the context of his earlier life, focusing on how and why he created such a public persona and how he adapted it in response to changing circumstances. It then considers the implications and effectiveness of this persona by assessing how it was perceived and narrated by others, acknowledging, in the process, why different groups engaged with and interpreted it differently

An examination of the psychometric structure of the Multidimensional Pain Inventory in temporomandibular disorder patients: a confirmatory factor analysis

BACKGROUND: This paper seeks to analyse the psychometric and structural properties of the Multidimensional Pain Inventory (MPI) in a sample of temporomandibular disorder patients. METHODS: The internal consistency of the scales was obtained. Confirmatory Factor Analysis was carried out to test the MPI structure section by section in a sample of 114 temporomandibular disorder patients. RESULTS: Nearly all scales obtained good reliability indexes. The original structure could not be totally confirmed. However, with a few adjustments we obtained a satisfactory structural model of the MPI which was slightly different from the original: certain items and the Self control scale were eliminated; in two cases, two original scales were grouped in one factor, Solicitous and Distracting responses on the one hand, and Social activities and Away from home activities, on the other. CONCLUSION: The MPI has been demonstrated to be a reliable tool for the assessment of pain in temporomandibular disorder patients. Some divergences to be taken into account have been clarified