“It’s not like family, it is family”: reflections on a mentoring program for boys of color

Early adolescence is a time of great potential and vulnerability, especially for boys of color. Research is replete with examples of how mentoring can help young people through this challenging period, but less is known about what students themselves want from such relationships. Tina Durand interviewed and conducted focus groups with boys of color participating in an after-school mentoring program to learn what they valued in a mentor. Common themes included mentors’ ability to relate to students; their unconditional support; their affirmation of students’ best traits, especially in the face of racial stereotypes; and their ability to inspire students.Accepted manuscrip

Finite element stress analysis of polymers at high strains

A numerical analysis is presented for the problem of a flat rectangular rubber membrane with a circular rigid inclusion undergoing high strains due to the action of an axial load. The neo-hookean constitutive equations are introduced into the general purpose TITUS program by means of equivalent hookean constants and initial strains. The convergence is achieved after a few iterations. The method is not limited to any specific program. The results are in good agreement with those of a company sponsored photoelastic stress analysis. The theoretical and experimental deformed shapes also agree very closely with one another. For high strains it is demonstrated that using the conventional HOOKE law the stress concentration factor obtained is unreliable in the case of rubberlike material

Continuity and variability in the parental involvement and advocacy beliefs of Latino families of young children

Parental involvement is an important component of children’s school success. Although the literature on parental involvement among Latino families is growing and moving from deficit-based perspectives, very few studies have examined the parental involvement beliefs and practices of Latino families who vary across demographic and sociocultural lines within the same school community. This qualitative study explored Latino parents’ beliefs about children’s education, their involvement and advocacy beliefs and practices, and their perceptions of feeling welcome at their children’s school. In-depth interviews were conducted with 12 parents of preschool and kindergarten children who attended a bilingual school. Qualitative descriptive analyses revealed that the majority of parents espoused the cultural value of educación, engaged in learning activities at home, and viewed themselves as living models of behavior for children, regardless of their education or immigrant status. Only first generation immigrant parents made explicit reference to children’s futures. All parents attributed supportive relationships with school personnel and a bilingual climate as the most important sources of feeling welcome at school. However, parents with more education valued what they perceived as an “open door policy” and were more vocal in critiquing policies. Findings have implications for the development of multicultural competence among teachers and for ways diverse Latino families might develop a shared voice within the school sector.Published versio

Computed tomography and magnetic resonance diagnosis of variations in the anatomical location of the major salivary glands in 1680 dogs and 187 cats

During assessment of routine clinical magnetic resonance imaging (MRI) of the heads of dogs, variations in the location of mandibular and zygomatic salivary glands (SGs) were observed incidentally. The aims of this retrospective study were to describe anatomical variations of the major SGs found on MRI and computed tomography (CT) studies of the head in dogs and cats and to investigate possible clinical relevancy. No anatomical variation of the SGs was seen in cats, but in dogs, although variation of the parotid SG was not identified, that of the mandibular SG was found in 33/1680 animals (2%), either unilaterally (6/33 right-sided, 13/33 left-sided) or bilaterally (14/33). The Border terrier breed (19/33, 58%) was over-represented. Each atypically located mandibular SG was positioned medial to the digastric muscle and rostral to the retropharyngeal lymph node. The sublingual glands were difficult to delineate from the mandibular glands. Anatomical variation of one zygomatic gland (3/4 left-sided) was identified in four small-breed dogs (0.2%). Each atypically located zygomatic gland was tilted at the ventrorostral aspect of the masseter muscle underneath the skin surface. MRI and CT characteristics were not different between typically and atypically located SGs. None of the dogs had clinical signs related with SG disease. It was concluded that, with suspected breed predispositions, incidental unilateral or bilateral anatomical variations of mandibular and zygomatic SGs can be encountered in dogs and an awareness of these possible variations may be important in pre-surgical planning

Fractional supersymmetric Quantum Mechanics as a set of replicas of ordinary supersymmetric Quantum Mechanics

A connection between fractional supersymmetric quantum mechanics and ordinary supersymmetric quantum mechanics is established in this Letter.Comment: Paper accepted for publication in Physics Letters

Hyperphosphorylation amplifies UPF1 activity to resolve stalls in nonsense-mediated mRNA decay.

Many gene expression factors contain repetitive phosphorylation sites for single kinases, but the functional significance is poorly understood. Here we present evidence for hyperphosphorylation as a mechanism allowing UPF1, the central factor in nonsense-mediated decay (NMD), to increasingly attract downstream machinery with time of residence on target mRNAs. Indeed, slowing NMD by inhibiting late-acting factors triggers UPF1 hyperphosphorylation, which in turn enhances affinity for factors linking UPF1 to decay machinery. Mutational analyses reveal multiple phosphorylation sites contributing to different extents to UPF1 activity with no single site being essential. Moreover, the ability of UPF1 to undergo hyperphosphorylation becomes increasingly important for NMD when downstream factors are depleted. This hyperphosphorylation-dependent feedback mechanism may serve as a molecular clock ensuring timely degradation of target mRNAs while preventing degradation of non-targets, which, given the prevalence of repetitive phosphorylation among central gene regulatory factors, may represent an important general principle in gene expression