5,252 research outputs found
The Hair Dilemma: Conform to Mainstream Expectations or Emphasize Racial Identity
Throughout American history, skin color, eye color, and hair texture have had the power to shape the quality of Black people\u27s lives, and that trend continues today for Black women in the workplace
Currency Option Pricing in Credible Target Zones
This paper develops a model for valuing options on a currency which is maintained within a band. The starting point of our model is the well known Krugman model for exchange-rate behavior within a target zone. Results from model runs provide insight into evidence reported by other authors of mispricing of currency options by extensions of the Black-Scholes model.
Reduction of trimethylamine N-oxide to trimethylamine by the human gut microbiota: supporting evidence for ‘metabolic retroversion’
Dietary sources of methylamines such as choline, trimethylamine (TMA), trimethylamine N-oxide (TMAO), phosphatidylcholine (PC) and carnitine are present in a number of foodstuffs, including meat, fish, nuts and eggs. It is recognized that the gut microbiota is able to convert choline to TMA in a fermentation-like process. Similarly, PC and carnitine are converted to TMA by the gut microbiota. It has been suggested that TMAO is subject to ‘metabolic retroversion’ in the gut (i.e. it is reduced to TMA by the gut microbiota, with this TMA being oxidized to produce TMAO in the liver). Sixty-six strains of human faecal and caecal bacteria were screened on solid and liquid media for their ability to utilize trimethylamine N-oxide (TMAO), with metabolites in spent media profiled by Proton Nuclear Magnetic Resonance (1H NMR) spectroscopy. Enterobacteriaceae produced mostly TMA from TMAO, with caecal/small intestinal isolates of Escherichia coli producing more TMA than their faecal counterparts. Lactic acid bacteria (enterococci, streptococci, bifidobacteria) produced increased amounts of lactate when grown in the presence of TMAO, but did not produce large amounts of TMA from TMAO. The presence of TMAO in media increased the growth rate of Enterobacteriaceae; while it did not affect the growth rate of lactic acid bacteria, TMAO increased the biomass of these bacteria. The positive influence of TMAO on Enterobacteriaceae was confirmed in anaerobic, stirred, pH-controlled batch culture fermentation systems inoculated with human faeces, where this was the only bacterial population whose growth was significantly stimulated by the presence of TMAO in the medium. We hypothesize that dietary TMAO is used as an alternative electron acceptor by the gut microbiota in the small intestine/proximal colon, and contributes to microbial population dynamics upon its utilization and retroversion to TMA, prior to absorption and secondary conversion to TMAO by hepatic flavin-containing monooxygenases. Our findings support the idea that oral TMAO supplementation is a physiologically-stable microbiota-mediated strategy to deliver TMA at the gut barrier
Extreme AO Observations of Two Triple Asteroid Systems with SPHERE
We present the discovery of a new satellite of asteroid (130) Elektra -
S/2014 (130) 1 - in differential imaging and in integral field spectroscopy
data over multiple epochs obtained with SPHERE/VLT. This new (second) moonlet
of Elektra is about 2 km across, on an eccentric orbit and about 500 km away
from the primary. For a comparative study, we also observed another triple
asteroid system (93) Minerva. For both systems, component-resolved reflectance
spectra of the satellites and primary were obtained simultaneously. No
significant spectral difference was observed between the satellites and the
primary for either triple system. We find that the moonlets in both systems are
more likely to have been created by sub-disruptive impacts as opposed to having
been captured.Comment: 8 pages, 4 figures, 1 table, accepted to be published in the
Astrophysical Journal Letter
Temperature control of the Mariner Venus 67 spacecraft
Temperature control design, instrumentation, and performance characteristics of Mariner 5 spacecraf
Metabolic profiling and phenotyping of central nervous system diseases: metabolites bring insights into brain dysfunctions
Preliminary Characterization of the O4+ Beam in Linac 3
The new GTS-LHC ECR ion source was installed in 2005. An oxygen 4+ beam was delivered to LEIR both for injection line (June 2005) and for the ring commissioning (September to December 2005). During these runs, studies were made of the beam transport in the Linac and towards LEIR. Some of the most significant results concerning the Linac are presented in this report. From 2006 the ECR source and the Linac3 delivered a lead beam for the LEIR commissioning, leaving some questions open for the oxygen beam transport. This report serves as a summary of the status of the investigations on the oxygen beam
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