33 research outputs found

    Barriers and facilitators of oral health care experienced by nursing home staff

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    Objectives to explore attitudes, perceptions, and perceived barriers to and the perceived facilitators of daily oral health care and the actual daily oral health care performances among nursing home staff. Methods A mixed methods study in 21 nursing homes was completed; a) questionnaires for nursing staff and managers; b) focus group interviews with nursing staff. Results 409 (21%) questionnaires were completed by nursing staff and 14 focus group interviews organized. Conclusions attitude was not a barrier in this study, while oral care was not performed according to guidelines. Nursing staff reported a lack of products, while toothbrushes are available. The most frequently mentioned barriers were lack of support of dental staff, oral care for clients with cognitive impairment, and a lack of education. Increasing facilitators could be; more (practical) education combined with tailored advice from internal dental staff. Where and on whom will the research have an impact? Nursing home staff, nursing home organizations/ managers and dental professionals working in nursing homes.</p

    Bringing an Equity Lens to EOS Research: Report of workshop findings and outcomes

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    On April 25, 2023 the JEDI-EOS group sponsored a workshop entitled Bringing an Equity Lens to EOS Research at the University of New Hampshire (UNH) in the Piscataqua Room at the Holloway Commons. The stated goal of the workshop was to synthesize and coordinate UNH’s efforts on geoscience topics impacting the health and well-being of under-served communities locally and regionally. The workshop welcomed approximately 35 participants primarily from the University of New Hampshire, but with representation from the NH Conservation Law Foundation, US Geological Survey, and NH Department of Environmental Services. A keynote address was provided by Dr. Daniel Faber from the Northeastern Environmental Justice Research Collaborative. The workshop entailed several session topics with ample time for discussion. At the conclusion of the workshop, participants were requested to provide a summary of their learning and opinions of important topics and 23 participants, including some members of the organizing committee, provided feedback that is summarized below. Many topics discussed throughout the day resonated with most of the participants, with many participants communicating that key factors that can enable more inclusive and equitable research outcomes include: Centering communities: Research in geoscience topics should reflect the needs and ideals of potentially affected communities. Boundary spanning: Researchers must leverage the existing roles of boundary spanners to interact successfully with communities. Institutional change: The timelines, incentives, and funding cycles of academic research should be reinvented to align with the needs of communities. Though these factors are identified as pre-requisites for furthering the academy’s commitment to equitable research, there remain significant unknowns in the proper path forward to achieving the ideals they represent

    Clinical oxidative stress during leprosy multidrug therapy:impact of dapsone oxidation

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    This study aims to assess the oxidative stress in leprosy patients under multidrug therapy (MDT; dapsone, clofazimine and rifampicin), evaluating the nitric oxide (NO) concentration, catalase (CAT) and superoxide dismutase (SOD) activities, glutathione (GSH) levels, total antioxidant capacity, lipid peroxidation, and methemoglobin formation. For this, we analyzed 23 leprosy patients and 20 healthy individuals from the Amazon region, Brazil, aged between 20 and 45 years. Blood sampling enabled the evaluation of leprosy patients prior to starting multidrug therapy (called MDT 0) and until the third month of multidrug therapy (MDT 3). With regard to dapsone (DDS) plasma levels, we showed that there was no statistical difference in drug plasma levels between multibacillary (0.518±0.029 μg/mL) and paucibacillary (0.662±0.123 μg/mL) patients. The methemoglobin levels and numbers of Heinz bodies were significantly enhanced after the third MDTsupervised dose, but this treatment did not significantly change the lipid peroxidation and NO levels in these leprosy patients. In addition, CAT activity was significantly reduced in MDT-treated leprosy patients, while GSH content was increased in these patients. However, SOD and Trolox equivalent antioxidant capacity levels were similar in patients with and without treatment. These data suggest that MDT can reduce the activity of some antioxidant enzyme and influence ROS accumulation, which may induce hematological changes, such as methemoglobinemia in patients with leprosy. We also explored some redox mechanisms associated with DDS and its main oxidative metabolite DDS-NHOH and we explored the possible binding of DDS to the active site of CYP2C19 with the aid of molecular modeling software

    Barriers and facilitators of oral health care experienced by nursing home staff

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    Objectives to explore attitudes, perceptions, and perceived barriers to and the perceived facilitators of daily oral health care and the actual daily oral health care performances among nursing home staff. Methods A mixed methods study in 21 nursing homes was completed; a) questionnaires for nursing staff and managers; b) focus group interviews with nursing staff. Results 409 (21%) questionnaires were completed by nursing staff and 14 focus group interviews organized. Conclusions attitude was not a barrier in this study, while oral care was not performed according to guidelines. Nursing staff reported a lack of products, while toothbrushes are available. The most frequently mentioned barriers were lack of support of dental staff, oral care for clients with cognitive impairment, and a lack of education. Increasing facilitators could be; more (practical) education combined with tailored advice from internal dental staff. Where and on whom will the research have an impact? Nursing home staff, nursing home organizations/ managers and dental professionals working in nursing homes

    Barriers and facilitators of oral health care experienced by nursing home staff

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    Objectives to explore attitudes, perceptions, and perceived barriers to and the perceived facilitators of daily oral health care and the actual daily oral health care performances among nursing home staff. Methods A mixed methods study in 21 nursing homes was completed; a) questionnaires for nursing staff and managers; b) focus group interviews with nursing staff. Results 409 (21%) questionnaires were completed by nursing staff and 14 focus group interviews organized. Conclusions attitude was not a barrier in this study, while oral care was not performed according to guidelines. Nursing staff reported a lack of products, while toothbrushes are available. The most frequently mentioned barriers were lack of support of dental staff, oral care for clients with cognitive impairment, and a lack of education. Increasing facilitators could be; more (practical) education combined with tailored advice from internal dental staff. Where and on whom will the research have an impact? Nursing home staff, nursing home organizations/ managers and dental professionals working in nursing homes
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