Effectiveness of dog rabies vaccination programmes: comparison of owner-charged and free vaccination campaigns

We investigated the percentage of dogs that could be vaccinated against rabies by conducting a pilot campaign in N'Djaména, Chad. Owners were charged US$4.13 per dog vaccinated, and 24$7623, resulting in an average of US$19.40 per vaccinated dog. This is five times more expensive than the cost per animal vaccinated during a previous free vaccination campaign for dog-owners, conducted in the same districts. The free campaign, which vaccinated 2605 more dogs than this campaign, cost an additional US$1.45 per extra dog vaccinated. Campaigns in which owners are charged for vaccinations result in lower vaccination rates than in free campaigns. Public health officials can use these results when evaluating the costs and benefits of subsidizing dog rabies vaccination programme

Survey of animal bite injuries and their management for an estimate of human rabies deaths in N'Djaména, Chad

To estimate the annual human rabies incidence as a baseline prior to mass dog vaccination campaigns in N'Djaména, Chad.; Survey of animal bites, involving 50% of all healthcare providers in N'Djaména, from September 2008 to April 2009. Of 86 people exposed to a suspected rabid animal, 50% received post-exposure vaccination and a further 8% had their wound cleaned. We estimated annual incidence of bites from suspected rabid animals of 12.9/100 000 and an incidence of 0.7 human rabies deaths/100 000, resulting in 7 estimated deaths (95% confidence interval 4-10 deaths) per year in N'Djaména. 14% of bite victims sought help from veterinarians.; Closer cooperation between physicians and veterinarians warrants more effective rabies control. The high proportion (42%) of potentially exposed people without post-exposure vaccination or wound treatment necessitates urgent attention

Human and livestock trematode infections in a mobile pastoralist setting at Lake Chad: added value of a One Health approach beyond zoonotic diseases research

Abstract Background At Lake Chad in Central Africa, mobile pastoralists face economic losses due to livestock trematodiases. Fasciola gigantica and Schistosoma bovis—trematodes that affect livestock—share transmission ecology traits with Schistosoma haematobium and S. mansoni that cause human schistosomiasis. This project aimed at assessing treatment strategies and elucidating the predictive potential of human and livestock trematode infections. Methods Schistosomiasis and fascioliasis were investigated concurrently in humans and cattle by repeated cross-sectional surveys. Urine and stool samples from humans and faecal samples from cattle were examined for trematode eggs. Treatment strategies were assessed by means of focus group discussions and in-depth interviews. Results Mobile pastoralists of four ethnic groups participated. Prevalence of human schistosomiasis and livestock trematodiases showed considerable heterogeneity from one ethnic group to another, but correlated within ethnic groups. Effective trematocidal drugs were not available in the study area. Conclusions Mutual predictive potential of human schistosomiasis and livestock fascioliasis relates to distinct livestock husbandry practices. Introducing efficacious strategic treatment against human schistosomiasis and livestock fascioliasis might improve human and animal health and well-being. Our research provides evidence for the benefits of a One Health approach targeting diseases that share specific ecological traits

Human and livestock trematode infections in a mobile pastoralist setting at Lake Chad : added value of a One Health approach beyond zoonotic diseases research

At Lake Chad in Central Africa, mobile pastoralists face economic losses due to livestock trematodiases. Fasciola gigantica and Schistosoma bovis-trematodes that affect livestock-share transmission ecology traits with Schistosoma haematobium and S. mansoni that cause human schistosomiasis. This project aimed at assessing treatment strategies and elucidating the predictive potential of human and livestock trematode infections.; Schistosomiasis and fascioliasis were investigated concurrently in humans and cattle by repeated cross-sectional surveys. Urine and stool samples from humans and faecal samples from cattle were examined for trematode eggs. Treatment strategies were assessed by means of focus group discussions and in-depth interviews.; Mobile pastoralists of four ethnic groups participated. Prevalence of human schistosomiasis and livestock trematodiases showed considerable heterogeneity from one ethnic group to another, but correlated within ethnic groups. Effective trematocidal drugs were not available in the study area.; Mutual predictive potential of human schistosomiasis and livestock fascioliasis relates to distinct livestock husbandry practices. Introducing efficacious strategic treatment against human schistosomiasis and livestock fascioliasis might improve human and animal health and well-being. Our research provides evidence for the benefits of a One Health approach targeting diseases that share specific ecological traits

The use of mobile phones for demographic surveillance of mobile pastoralists and their animals in Chad : proof of principle

Demographic information is foundational for the planning and management of social programmes, in particular health services. The existing INDEPTH network surveillance sites are limited to coverage of sedentary populations. Including mobile populations in this approach would be expensive, time consuming and possibly low in accuracy. Very little is known about the demography of mobile pastoralists and their animals, so innovative approaches are urgently needed.; To test and evaluate a mobile demographic surveillance system for mobile pastoralist households, including livestock herds, using mobile phones.; Mobile pastoralist camps were monitored (10 for 12 months and 10 for 18 months) using biweekly mobile phone calls with camp leaders and their wives to conduct interviews about the households and livestock. The collected information was validated through personal visits, GPS data and a livestock demographic model.; The study showed the feasibility of mobile phone surveillance for mobile pastoralist camps, providing usable, valid information on human and livestock population structures, pregnancy outcomes and herd dynamics, as well as migration patterns. The approach was low-cost and applicable with the existing local resources.; Demographic surveillance in mobile populations is feasible using mobile phones. Expansion of the small-scale system into a full mobile demographic surveillance system is warranted and would likely lead to improved planning and provision of human and animal health care